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公开(公告)号:US20120283106A1
公开(公告)日:2012-11-08
申请号:US13397572
申请日:2012-02-15
申请人: Kai WANG , Shile ZHANG , David GALAS
发明人: Kai WANG , Shile ZHANG , David GALAS
CPC分类号: C12Q1/6851 , C12Q1/6883 , C12Q2600/178 , C40B20/00 , C12Q2525/173 , C12Q2525/191 , C12Q2525/207
摘要: Improved methods to quantitate RNA in biological or other analytical samples employ extended RNAs containing adaptors at the 5′ end and polyA sequences coupled to a tag at the 3′ end. The invention method is particularly useful in quantitating microRNAs as primers can be used that need not complement the non-conserved 3′ ends of these molecules.
摘要翻译: 在生物或其他分析样品中定量RNA的改进方法使用在5'端含有衔接子的延伸RNA和在3'末端与标签偶联的polyA序列。 本发明方法特别可用于定量微小RNA,因为可以使用不需要补充这些分子的非保守3'末端的引物。
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公开(公告)号:US20120252871A1
公开(公告)日:2012-10-04
申请号:US13423129
申请日:2012-03-16
申请人: David GALAS , Kai WANG , Guy BERCHEM , Etienne MOUSSAY
发明人: David GALAS , Kai WANG , Guy BERCHEM , Etienne MOUSSAY
IPC分类号: A61K31/7105 , C12Q1/68 , A61P35/02
CPC分类号: C12Q1/6886 , C12Q2600/178
摘要: New markers in the form of miRNA levels in plasma are provided for indicating the presence of CLL in a subject as well as suggesting routes of therapeutic treatment.
摘要翻译: 提供血浆中miRNA水平形式的新标记物,用于指示受试者中CLL的存在以及建议治疗性治疗途径。
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