公开(公告)号：US20230119862A1

公开(公告)日：2023-04-20

申请号：US17907188

申请日：2021-03-19

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyun Gyu PARK ,  Jayeon SONG ,  Hyo Yong KIM ,  Yujin JUNG

IPC: C12Q1/6876 ,  C12Q1/686

Abstract: The present invention relates to a self-priming hairpin-mediated isothermal amplification (SP-HAMP) and, more specifically, to a hairpin probe having a self-priming structure, which is for detecting a target nucleic acid and can be used in the nucleic acid isothermal amplification, and to a method for detecting a target nucleic acid by using same. The SP-HAMP technique according to the present invention is convenient due to no need of a separate primer with a complicated design required in existing LAMP technology, has improved efficiency of detection compared with existing LAMP reactions, and can detect DNA as well as RNA as a target nucleic acid, and therefore the technique according to the present invention can be applied in a wider variety of fields.