公开(公告)号：US20240127908A1

公开(公告)日：2024-04-18

申请号：US18142958

申请日：2024-01-03

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jung Kyoon CHOI ,  Joon Ha KWON

IPC: G16B40/00 ,  G16B25/10

CPC classification number: G16B40/00 ,  G16B25/10

Abstract: A method for discovering a target antigen for a chimeric antigen receptor comprises the steps of: obtaining, by an analysis apparatus, expression information of genes of tumor cells in single cell units; extracting, by the analysis apparatus, from among the genes, genes of candidate antigens having an expression level of a reference value or more; determining, by the analysis apparatus, all possible gene combinations that can be constituted by the genes of the candidate antigens; and determining, by the analysis apparatus, a target gene combination in which at least one gene included therein is expressed, among the gene combinations.