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公开(公告)号：US10337016B2
公开(公告)日：2019-07-02
申请号：US15327596
申请日：2016-10-14
Inventor： Byong-Seok Choi , Suk-Jo Kang , Janghyun Lee , Ji Youn Min , Dongmin Chun , Si-Eun Sung
IPC: C12N15/117 , A61K31/713 , C12N15/113
Abstract: The present disclosure provides a pharmaceutical composition for treating cancer comprising an RNA oligonucleotide having a particular sequence and structure. Specifically, when a cell line is treated with an RNA oligonucleotide having specific sequence and helical bend structure according to the present disclosure, the expression of ISG56 is increased and apoptosis of cancer cells is induced. Thus, a composition comprising the RNA oligonucleotide can be used as an anticancer agent.
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