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    High resolution volumetric image generation based on super resolution post-processing and point spread function
    1.
    发明授权
    High resolution volumetric image generation based on super resolution post-processing and point spread function 有权
    基于超分辨率后处理和点扩散功能的高分辨率体积图像生成

    公开(公告)号：US09595079B2

    公开(公告)日：2017-03-14

    申请号：US14376856

    申请日：2013-01-30

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Yechiel Lamash ,  Liran Goshen

    IPC: G06K9/00 ,  G06T3/40 ,  G06T3/00 ,  G06T11/00

    CPC classification number: G06T3/4053 ,  G06T3/0068 ,  G06T11/003

    Abstract: In one aspect, a method for generating higher resolution volumetric image data from lower resolution volumetric image data includes receiving volumetric image data of a scanned subject, wherein the volumetric image data includes data representing a periodically moving structure of interest of the scanned subject, and wherein the volumetric image data covers multiple motion cycles of the periodically moving structure of interest. The method further includes estimating inter-image motion between neighboring images of the received volumetric image data. The method further includes registering the received volumetric image data based at least on the estimated inter-image motion. The method further includes generating the higher resolution volumetric image data based on the registered volumetric image data, a super resolution post-processing algorithm, and a point spread function of an imaging system that generated the volumetric image data. The higher resolution volumetric image data has an image resolution that is greater than the lower resolution volumetric image data.

    Abstract translation: 在一个方面，一种用于从较低分辨率的体积图像数据产生较高分辨率的体积图像数据的方法包括：接收被扫描的对象的体积图像数据，其中，体积图像数据包括表示所扫描的对象感兴趣的周期性移动结构的数据，并且其中 体积图像数据涵盖周期性移动的感兴趣结构的多个运动周期。 该方法还包括估计所接收的体积图像数据的相邻图像之间的图像间运动。 该方法还包括至少基于估计的图像间运动来注册所接收的体积图像数据。 该方法还包括基于注册的体积图像数据，超分辨率后处理算法和产生体积图像数据的成像系统的点扩散函数来生成更高分辨率的体积图像数据。 较高分辨率的体积图像数据具有大于较低分辨率体积图像数据的图像分辨率。

    Perfusion imaging
    2.
    发明授权
    Perfusion imaging 有权
    灌注成像

    公开(公告)号：US09299142B2

    公开(公告)日：2016-03-29

    申请号：US14350374

    申请日：2012-10-15

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Raz Carmi ,  Yechiel Lamash

    IPC: G06K9/00 ,  G06T7/00 ,  A61B6/03 ,  A61B6/00 ,  A61B5/026

    CPC classification number: G06T7/0012 ,  A61B5/026 ,  A61B6/032 ,  A61B6/486 ,  A61B6/507 ,  A61B6/5217

    Abstract: A perfusion imaging data processor (122) includes an agent peak characteristic-time determiner (206) configured to determine two or more agent peak characteristic-times respectively for two or more circulatory sub-systems represented in a same sub-set of voxels of a set of time-series data of perfusion imaging data, an agent peak argument determiner (210) configured to determine an agent peak argument for each of the two or more agent peak characteristic-times, an agent peak argument relation determiner (212) configured to determine a relationship between the agent peak arguments of the two or more agent peak characteristic-times, and a perfusion map generator (214) configured to generate, based on the determined relationship and the perfusion imaging data, at least one perfusion map, wherein the at least one perfusion map includes volumetric image data visually presenting at least one of a relationship or a difference between the two or more circulatory sub-systems.

    Abstract translation: 灌注成像数据处理器（122）包括代理峰值特征 - 时间确定器（206），其被配置为分别确定在同一子集的体素中表示的两个或更多个循环子系统的两个或更多个代理峰特征时间 一组代理峰值参数确定器（210），被配置为确定所述两个或多个代理峰值特征时间中的每一个的代理峰值参数;代理峰值参数关系确定器（212），被配置为 确定两个或多个代理峰值特征时间的代理峰值参数与被配置为基于确定的关系和灌注成像数据生成至少一个灌注图的灌注图生成器（214）之间的关系，其中， 至少一个灌注图包括视觉上呈现两个或多个循环子系统之间的关系或差异中的至少一个的体积图像数据。

    iFR-CT
    3.
    发明授权
    iFR-CT 有权

    公开(公告)号：US10646185B2

    公开(公告)日：2020-05-12

    申请号：US15542451

    申请日：2016-01-06

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Liran Goshen ,  Yechiel Lamash

    IPC: G06T7/62 ,  G06T7/00 ,  G16H50/50 ,  A61B6/00 ,  A61B5/00 ,  A61B5/02 ,  G16H30/20 ,  A61B6/03 ,  A61B5/026

    Abstract: A method includes for non-invasively determining an instantaneous wave-free ratio metric includes receiving electronically formatted image data generated by an imaging system. The image data includes voxels with intensities representative of a vessel with a stenosis. The method further includes computing peripheral resistances of outlets of the vessel from the image data. The method further includes calculating a stenosis resistance of the stenosis between an inlet of the vessel inlet and the outlets of the vessel based on a set of boundary conditions and a computational fluid dynamics algorithm. The method further includes calculating the instantaneous wave-free ratio metric. The metric is a numerical value, based on the stenosis resistance and generating a signal indicative of the calculated instantaneous wave-free ratio metric.

    Spectral image data processing
    5.
    发明授权
    Spectral image data processing 有权

    公开(公告)号：US10970836B2

    公开(公告)日：2021-04-06

    申请号：US15103985

    申请日：2014-12-03

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Yechiel Lamash ,  Liran Goshen ,  Raz Carmi

    IPC: G06T7/00 ,  A61B5/00 ,  A61B6/03 ,  A61B6/00

    Abstract: A method includes obtaining contrast enhanced spectral image data that includes voxels representing a tubular structure. The method further includes generating at least a contrast map based on the obtained contrast enhanced spectral image data. The method further includes generating an updated contrast map based on a spectral model. The method further includes segmenting the tubular structure based on updated contrast map. A computing system (120) includes a spectral analyzer (202) that receives contrast enhanced spectral image data and generates a spectral analysis data based thereon, wherein the spectral analysis data includes a contrast map, The computing system further includes a spectral analysis data processor (204) that refines the spectral analysis data, generating refined spectral analysis data.

    IMAGE RESOLUTION ENHANCEMENT
    7.
    发明申请
    IMAGE RESOLUTION ENHANCEMENT 有权
    图像分辨率增强

    公开(公告)号：US20140376795A1

    公开(公告)日：2014-12-25

    申请号：US14376856

    申请日：2013-01-30

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Yechiel Lamash ,  Liran Goshen

    IPC: G06T3/40 ,  G06T11/00 ,  G06T3/00

    CPC classification number: G06T3/4053 ,  G06T3/0068 ,  G06T11/003

    Abstract: In one aspect, a method for generating higher resolution volumetric image data from lower resolution volumetric image data includes receiving volumetric image data of a scanned subject, wherein the volumetric image data includes data representing a periodically moving structure of interest of the scanned subject, and wherein the volumetric image data covers multiple motion cycles of the periodically moving structure of interest. The method further includes estimating inter-image motion between neighboring images of the received volumetric image data. The method further includes registering the received volumetric image data based at least on the estimated inter-image motion. The method further includes generating the higher resolution volumetric image data based on the registered volumetric image data, a super resolution post-processing algorithm, and a point spread function of an imaging system that generated the volumetric image data. The higher resolution volumetric image data has an image resolution that is greater than the lower resolution volumetric image data.

    Abstract translation: 在一个方面，一种用于从较低分辨率的体积图像数据产生较高分辨率的体积图像数据的方法包括：接收被扫描的对象的体积图像数据，其中，体积图像数据包括表示所扫描的对象感兴趣的周期性移动结构的数据，并且其中 体积图像数据涵盖周期性移动的感兴趣结构的多个运动周期。 该方法还包括估计所接收的体积图像数据的相邻图像之间的图像间运动。 该方法还包括至少基于估计的图像间运动来注册所接收的体积图像数据。 该方法还包括基于注册的体积图像数据，超分辨率后处理算法和产生体积图像数据的成像系统的点扩散函数来生成更高分辨率的体积图像数据。 较高分辨率的体积图像数据具有大于较低分辨率体积图像数据的图像分辨率。

    Apparatus for determining a fractional flow reserve value
    8.
    发明授权
    Apparatus for determining a fractional flow reserve value 有权

    公开(公告)号：US10258303B2

    公开(公告)日：2019-04-16

    申请号：US15317158

    申请日：2015-06-24

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Michael Grass ,  Yechiel Lamash ,  Liran Goshen ,  Holger Schmitt ,  Mordechay Pinchas Freiman ,  Hannes Nickisch ,  Sven Prevrhal

    IPC: A61B5/04 ,  A61B6/00 ,  G16H50/50 ,  A61B5/02 ,  A61B6/03 ,  A61B6/06 ,  A61B5/029

    Abstract: The invention relates to an apparatus for determining a fractional flow reserve (FFR) value of the coronary artery system of a living being (3). A fractional flow reserve value determination unit (13) determines the FFR value by using an FFR value determination algorithm that is adapted to determine the FFR value based on a boundary condition and a provided representation of the coronary artery system, wherein the boundary condition is specific for the living being and determined by a boundary condition determination unit (12). Since the boundary condition determination unit determines a boundary condition, which is specific for the living being, and since the fractional flow reserve value determination unit not only uses the provided representation of the coronary artery system, but also the living being specific boundary condition for determining the FFR value, the accuracy of the FFR value, which is non-invasively determined, can be improved.

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