Dead pixel correction for digital PET reconstruction

    公开(公告)号:US10852448B2

    公开(公告)日:2020-12-01

    申请号:US16469605

    申请日:2017-12-06

    Abstract: A PET detector array (8) comprising detector pixels acquires PET detection counts along lines of response (LORs). The counts are reconstructed to generate a reconstructed PET image (36, 46). The reconstructing is corrected for missing LORs which are missing due to dead detector pixels of the PET detector array. The correction may be by estimating counts along the missing LORs (60) by interpolating counts along LORs (66) neighboring the missing LORs. The interpolation may be iterative to handle contiguous groups of missing detector pixels. The correction may be by computing a sensitivity matrix having matrix elements corresponding to image elements (80, 82) of the reconstructed PET image. In this case, each matrix element is computed as a summation over all LORs intersecting the corresponding image element excepting the missing LORs. The computed sensitivity matrix is used in the reconstructing.

    Standardized uptake value (SUV) guided reconstruction control for improved outcome robustness in positron emission tomography (PET) imaging

    公开(公告)号:US11158094B2

    公开(公告)日:2021-10-26

    申请号:US16474576

    申请日:2018-01-03

    Abstract: A nuclear medicine image reconstruction method generates a reconstructed image (44) by performing iterative image in reconstruction (30, 130) on nuclear medicine imaging data (22). The iterative image reconstruction produces a sequence of update images (34, 36, 134, 136). During the iterative image reconstruction, a standardized uptake value (SUV) transform (40) is applied to convert an update image (34, 36) to an update SUV image (42, 46). The SUV transform scales values of voxels of the update image to SUV values using scaling factors including at least a body size metric and a dose metric. During the iterative image reconstruction, at least one parameter used in an image update of the iterative image reconstruction is adjusted using the update SUV image. For example, a parameter of a prior or filter (38) incorporated into an image reconstruction update step (32) or used in filtering of an update image (36) may be adjusted.

Patent Agency Ranking