公开(公告)号：US20160038076A1

公开(公告)日：2016-02-11

申请号：US14378800

申请日：2013-03-01

申请人： KONINKLIJKE PHILIPS N.V

发明人： MANFRED MULLER ,  GERHARDUS WILHELMUS LUCASSEN ,  CHRISTIAN REICH ,  PAYAL KESWARPU

IPC分类号： A61B5/00 ,  A61B5/1455 ,  A61B5/145

CPC分类号： A61B5/444 ,  A61B5/0084 ,  A61B5/14546 ,  A61B5/14551 ,  A61B5/443 ,  A61B5/4872 ,  A61B5/7278 ,  A61B5/7282 ,  A61B2562/0238 ,  A61B2562/0242 ,  A61B2576/00

摘要： The invention relates to an apparatus for determining a property of a tissue, particularly cancer of cervical tissue. A light providing unit (7, 8, 9) provides light for illuminating the tissue (6) and a light detection unit (10) detects light from the tissue, wherein a first signal being indicative of light (11) having been influenced by an epithelium region (R1), a second signal being indicative of light (12) having been influenced by a boundary region (R2) and a third signal being indicative of light (13) having been influenced by a stroma region (R3) are generated, and wherein a tissue property is determined based on the first, second and third signals. This allows for an determination of a tissue property, which is based on a combination of optical properties measured in the three different regions, resulting in an improved determination of the tissue property, in particular in improved cancer detection.

摘要翻译： 本发明涉及一种用于确定组织，特别是宫颈组织癌症的性质的装置。 光提供单元（7,8,9）提供用于照亮组织（6）的光，并且光检测单元（10）检测来自组织的光，其中指示已经受到 产生表示受边界区域（R2）影响的光（12）的第二信号和表示已被基质区域（R3）影响的光（13）的第三信号的上皮区域（R1） 并且其中基于所述第一，第二和第三信号确定组织属性。 这允许基于在三个不同区域中测量的光学性质的组合来确定组织性质，导致组织性质的改进的确定，特别是在改进的癌症检测中。