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公开(公告)号：US20240024369A1
公开(公告)日：2024-01-25
申请号：US18283660
申请日：2022-03-24
Applicant: KING'S COLLEGE LONDON
Inventor： Fiona Watt , Christina PHILIPPEOS , Magnus LYNCH
CPC classification number: A61K35/33 , C12N5/0656 , A61K9/0014 , A61P17/02 , C12N2501/734 , C12N2501/73
Abstract: Provided herein is method of treating a skin condition in a subject, comprising isolating cells comprising primary dermal fibroblasts from a skin sample obtained from the subject, and administering the freshly-isolated cells to skin of the subject. Also provided are freshly isolated cell preparations comprising primary dermal fibroblasts and uses thereof.
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公开(公告)号：US20240279609A1
公开(公告)日：2024-08-22
申请号：US18490714
申请日：2023-10-19
Applicant: KING'S COLLEGE LONDON
Inventor： Fiona WATT , Christina PHILIPPEOS , Magnus LYNCH
CPC classification number: C12N5/0656 , A61K35/36 , C12N2501/115 , C12N2501/15 , C12N2501/415
Abstract: Provided herein is a method of sorting human dermal fibroblasts, comprising (a) providing a cell population comprising human dermal fibroblasts; and (b) separating the human dermal fibroblasts into subpopulations based on expression of one or more cell-surface markers selected from CD39, CD36 and CD26. Also provided are isolated populations of human dermal papillary fibroblasts and cosmetic and therapeutic uses thereof.
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公开(公告)号：US20210095252A1
公开(公告)日：2021-04-01
申请号：US16956500
申请日：2018-12-21
Applicant: KING'S COLLEGE LONDON
Inventor： Fiona WATT , Christina PHILIPPEOS , Magnus LYNCH
Abstract: Provided herein is a method of sorting human dermal fibroblasts, comprising (a) providing a cell population comprising human dermal fibroblasts; and (b) separating the human dermal fibroblasts into subpopulations based on expression of one or more cell-surface markers selected from CD39, CD36 and CD26. Also provided are isolated populations of human dermal papillary fibroblasts and cosmetic and therapeutic uses thereof.
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