公开(公告)号：US20250009653A1

公开(公告)日：2025-01-09

申请号：US18689579

申请日：2022-09-08

Applicant: KINDEVA DRUG DELIVERY L.P.

Inventor： Philip COCKS ,  Sarah WRIGGLESWORTH ,  Connor MCCORMACK ,  James LISTER ,  Lauren HARRISON ,  Chad HARALDSON ,  Joseph MILLER ,  James DRAKE ,  Stephen STEIN

IPC: A61K9/00 ,  A61K9/08 ,  A61K31/40 ,  A61K31/439 ,  A61K31/5386 ,  A61K47/06 ,  A61K47/10

Abstract: A composition comprising a solution comprising an active pharmaceutical ingredient comprising an anticholinergic agent, such as ipratropium bromide, and a propellant comprising HFA-152a, HFO-1234ze(E), or both. A metered dose inhaler comprising a metering valve a canister; and an actuator comprising an actuator nozzle; wherein the canister comprises said composition.

公开(公告)号：US20240382419A1

公开(公告)日：2024-11-21

申请号：US18689555

申请日：2022-09-08

Applicant: KINDEVA DRUG DELIVERY L.P.

Inventor： Philip COCKS ,  Alexander SLOWEY ,  Benjamin MYATT ,  Sarah WRIGGLESWORTH ,  James LISTER ,  Lauren HARRISON ,  Chad HARALDSON ,  Joseph MILLER ,  James DRAKE ,  Stephen STEIN

IPC: A61K9/00 ,  A61K31/137 ,  A61K31/55 ,  A61K31/573 ,  A61K47/06 ,  A61K47/10 ,  A61K47/12 ,  A61M15/00

Abstract: A metered dose inhaler comprising a metering valve, a canister, an actuator comprising an actuator nozzle, wherein the canister comprises a formulation, the formulation comprising greater than 70% by weight of propellant HFO-1234ze(E), and at least one active pharmaceutical ingredient dissolved in the formulation to form a solution, said active pharmaceutical ingredient preferably selected from beclomethasone, formoterol or tiotropium.