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公开(公告)号：US08991680B1
公开(公告)日：2015-03-31
申请号：US13211233
申请日：2011-08-16
CPC分类号： B23K1/19 , A61N1/0531
摘要： The electrode array is a device for making electrical contacts with cellular tissue or organs. The electrode array includes an assembly of electrically conductive electrodes arising from a substrate where the electrodes are hermetically bonded to the substrate. A method of manufacture of an electrode array and associated circuitry is disclosed where the braze preform tab disappears during the braze bonding process and is completely drawn into the substrate feedthrough holes such that the braze perform tab is completely involved in the braze joint and is no longer connecting the adjacent electrodes.
摘要翻译： 电极阵列是用于与细胞组织或器官进行电接触的装置。 电极阵列包括由电极产生的导电电极的组件，其中电极气密地结合到衬底上。 公开了一种制造电极阵列和相关联的电路的方法，其中钎焊预成型件接头在钎焊接合过程期间消失，并且完全拉入衬底馈通孔中，使得钎焊性能接头完全参与钎焊接头并且不再 连接相邻的电极。
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公开(公告)号：US08862235B1
公开(公告)日：2014-10-14
申请号：US11983674
申请日：2007-11-09
申请人： Howard H. Stover , John C. Gord , Charles L. Byers , Joseph H. Schulman , Guangqiang Jiang , Ross Davis
发明人： Howard H. Stover , John C. Gord , Charles L. Byers , Joseph H. Schulman , Guangqiang Jiang , Ross Davis
CPC分类号： A61B5/0478 , A61B5/0006 , A61B5/04012 , A61B5/686 , A61N1/36003 , A61N1/36017 , A61N1/36025 , A61N1/3605 , A61N1/36082
摘要： A brain implant device includes a housing containing communication and control electronics coupled to a conduit configured for monitoring signals from a brain's motor cortex and providing stimulation signals to the brain's sensory cortex. The brain implant device is capable of wireless communication with an external communication and control signal source by means of an antenna provided in the housing. The conduit is flexible and may contain upwards of 128 electrical conductors providing electrical connections between the device electronics and related sites on the motor and/or sensory cortex by means of a plurality of electrically conductive protuberances extending from the conduit and adapted for contact with such sites.
摘要翻译： 脑植入装置包括壳体，其包含耦合到导管的通信和控制电子器件，所述导管被配置用于监测来自大脑的运动皮质的信号并向大脑的感觉皮质提供刺激信号。 脑植入装置能够通过设置在壳体中的天线与外部通信和控制信号源进行无线通信。 导管是柔性的并且可以包含上部128个电导体，其借助于从导管延伸并适于与这些部位接触的多个导电突起，在装置电子设备和电动机和/或感觉皮质之间的相关部位提供电连接 。
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公开(公告)号：US08336191B1
公开(公告)日：2012-12-25
申请号：US11833887
申请日：2007-08-03
IPC分类号： H04R31/00
CPC分类号： H03H9/54 , H01L2224/48227 , H01L2224/48465 , H03H9/1021 , H05K13/04 , Y10T29/49005 , Y10T29/49007 , Y10T29/4908 , H01L2924/00
摘要： An electronics filter circuit includes an electromechanical resonator that is mounted directly to the surface of a silicon integrated circuit, rather than being a surface mounted or leaded filter can on a circuit board. This filter circuit allows the integrated circuit electronic package to be significantly smaller than a conventional electromechanical resonator package. The electromechanical resonator may be protected during processing and during use with a protective cover that is made of a material such as titanium. The protective cover is attached to the integrated circuit chip.
摘要翻译： 电子滤波器电路包括直接安装到硅集成电路的表面的机电谐振器，而不是在电路板上的表面安装或引线的过滤器罐。 该滤波器电路允许集成电路电子封装显着小于常规机电谐振器封装。 机械共振器可以在加工期间和使用期间由诸如钛的材料制成的保护盖保护。 保护盖连接到集成电路芯片。
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4.发明申请Video Processing Methods for Improving Visual Acuity and/or Perceived Image Resolution 有权用于改善视觉和/或感知图像分辨率的视频处理方法公开(公告)号：US20110288612A1
公开(公告)日：2011-11-24
申请号：US13196020
申请日：2011-08-02
申请人： Robert J. Greenberg , Richard P. Willamson , Joseph H. Schulman , Reza P. Rassool , Lee J. Mandell , Abraham N. Seidman
发明人： Robert J. Greenberg , Richard P. Willamson , Joseph H. Schulman , Reza P. Rassool , Lee J. Mandell , Abraham N. Seidman
IPC分类号： A61F9/08
CPC分类号： A61N1/36046
摘要： A method and apparatus for improving visual acuity when providing a visual image from a “high” resolution input device to a “low” resolution output device. The described invention is of particular use when the output device is an array of electrodes as part of a retinal prosthesis used to restore vision to a visually-impaired patient. In that various limitations may, within the foreseeable future, limit the density of such an electrode array (and thus the resolution of the output image), the present invention teaches techniques to assign processed pixel subsets of a higher resolution image to a single electrode. By varying the pixel subsets, e.g., by jittering, and/or altering the processing criteria, the perceived visual acuity may be further improved. Alternatively and additionally, such processing may be further extended to drive neighboring electrodes in combination to thus stimulate virtual electrode sites and thus further enhance visual acuity.
摘要翻译： 当从“高”分辨率输入装置向“低”分辨率输出装置提供视觉图像时，用于提高视力的方法和装置。 当输出设备是用作将视力恢复到视觉障碍患者的视网膜假体的一部分的电极阵列时，所描述的本发明是特别有用的。 因此，在可预见的将来可能会限制这种电极阵列的密度（因此输出图像的分辨率）的各种限制，本发明教导了将更高分辨率图像的经处理的像素子集分配给单个电极的技术。 通过例如通过抖动和/或改变处理标准来改变像素子集，可以进一步改善感知的视敏度。 另外地和另外地，这样的处理可以进一步延伸以组合驱动相邻电极，从而刺激虚拟电极位置，从而进一步提高视敏度。
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公开(公告)号：US08055336B1
公开(公告)日：2011-11-08
申请号：US11871776
申请日：2007-10-12
申请人： Joseph H. Schulman , Yitzhak Zilberman , Kate E. Purnell , Martin J. Vogel , Adam Vogel, legal representative
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61B5/6882 , A61N1/36003 , A61N1/372 , A61N1/37205 , A61N2001/0578
摘要： A method of removing an implantable electronic microdevice by an integral removal loop or circumferential ring to facilitate removal of the implanted microdevice without additional surgery. The device is removed by pulling it along the surgically created implantation path. Optionally a radio-opaque tether provides a method of locating the implantable microdevice without additional surgery and attachment of one end of the tether to a radio-opaque marker provides a method of locating the end of the tether to facilitate removal of the implantable microdevice from living tissue.
摘要翻译： 一种通过整体移除环或周向环移除可植入电子微型装置的方法，以便于无需另外手术即可移除植入的微型装置。 通过沿着手术产生的植入路径拉动装置来移除该装置。 可选地，不透射线的系绳提供了一种定位可植入微型装置的方法，而无需额外的手术，并且将系绳的一端附接到不透射线的标记物提供了一种定位系绳端部以便于移除可植入微型装置从生活的方法 组织。
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公开(公告)号：US07957810B2
公开(公告)日：2011-06-07
申请号：US11926041
申请日：2007-10-28
IPC分类号： A61N1/18
CPC分类号： A61N1/0543 , A61N1/36046 , A61N1/37247 , A61N1/375 , H01L2224/16225 , Y10T29/49165
摘要： The present invention is a motion compensation system for a visual prosthesis to adapt a visual image to movement of a user's eyes and head. The system includes a camera providing a video signal, an eye movement tracking device, a head movement tracking device, and a video processing unit processing the video signal and correcting the video signal for eye and head movement. The corrected video signal is sent to an implanted neural stimulator including electrodes stimulating visual neurons to create a perception of the video image.
摘要翻译： 本发明是用于视觉假体的运动补偿系统，以使视觉图像适应用户的眼睛和头部的运动。 该系统包括提供视频信号的相机，眼动跟踪装置，头部移动跟踪装置和视频处理单元，其处理视频信号并校正视频信号以进行眼睛和头部运动。 校正的视频信号被发送到植入的神经刺激器，其包括刺激视觉神经元的电极以产生视频图像的感知。
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公开(公告)号：US07894911B2
公开(公告)日：2011-02-22
申请号：US11206484
申请日：2005-08-17
IPC分类号： A61N1/04
CPC分类号： A61N1/0543 , A61N1/36046 , A61N1/37247 , A61N1/375 , H01L2224/16225 , Y10T29/49165
摘要： The stimulation device is an improved array for neuro-stimulation. The electrode array of the stimulation device is ideally suited for a visual prosthesis for the restoration of sight in patients with lost or degraded visual function. The electrode array of the stimulation device improves connectivity between a prosthesis and neurons.
摘要翻译： 刺激装置是用于神经刺激的改进阵列。 刺激装置的电极阵列理想地适合视觉假体，用于在具有丢失或退化的视觉功能的患者中恢复视力。 刺激装置的电极阵列改善假体和神经元之间的连接。
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8.发明申请Logarithmic Light Intensifier for use with Photoreceptor-Based Implanted Retinal Prosthetics and those Prosthetics 有权用于基于光感受器的植入视网膜假体和这些假体的对数光增强剂公开(公告)号：US20090204212A1
公开(公告)日：2009-08-13
申请号：US12425236
申请日：2009-04-16
CPC分类号： A61N1/36046 , A61F9/08
摘要： This invention is for directly modulating a beam of photons onto the retinas of patients who have extreme vision impairment or blindness. Its purpose is to supply enough imaging energy to retinal prosthetics implanted in the eye which operate essentially by having light (external to the eye) activating photoreceptors, or photoelectrical material. The invention provides sufficient light amplification and does it logarithmically. While it has sufficient output light power, the output light level still remains at a safe level. Most preferred embodiments of this invention provide balanced biphasic stimulation with no net charge injection into the eye. Both optical and electronic magnification for the image, as for example, using an optical zoom lens, is incorporated. Otherwise, it would not be feasible to zoom in on items of particular interest or necessity. Without proper adjustment, improper threshold amplitudes would obtain, as well as uncomfortable maximum thresholds. Therefore, to adjust for these, a way of proper adjustment for the threshold amplitudes and maximum comfortable thresholds is provided. Furthermore, to the extent that the individual stimulation sites in the retina give different color perceptions, upon stimulation, then colors of the viewed scene is correlated with specific stimulation sites to provide a certain amount of color vision.
摘要翻译： 本发明用于将光束束直接调制到具有极端视力障碍或失明的患者的视网膜上。 其目的是为植入眼睛的视网膜假体提供足够的成像能量，其基本上通过使光（外部的眼睛）激活光感受器或光电材料。 本发明提供足够的光放大，并且它是对数的。 虽然它具有足够的输出光功率，但输出光级仍然保持在一个安全的水平。 本发明最优选的实施方案提供平衡的双相刺激，而没有净电荷注入眼睛。 包括用于图像的光学和电子倍率，例如使用光学变焦透镜。 否则，放大特别感兴趣或必要的项目是不可行的。 没有适当的调整，不正确的阈值振幅将获得，以及不舒适的最大阈值。 因此，为了适应这些，提供了适当调整阈值振幅和最大舒适阈值的方法。 此外，在视网膜中的个别刺激部位产生不同的颜色感觉的情况下，在刺激时，所观看场景的颜色与特定刺激部位相关，以提供一定量的色觉。
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9.发明授权System of implantable devices for monitoring and/or affecting body parameters 有权用于监测和/或影响身体参数的可植入装置的系统公开(公告)号：US07513257B2
公开(公告)日：2009-04-07
申请号：US11187290
申请日：2005-07-21
CPC分类号： A61N1/37211 , A61B5/0031 , A61B5/053 , A61B5/07 , A61B5/145 , A61B5/14532 , A61B5/4519 , A61B5/4528 , A61B2560/0219 , A61B2562/08 , A61F2/72 , A61F2002/5058 , A61F2002/704 , A61F2002/705 , A61N1/37205 , A61N1/37252 , A61N1/37288 , A61N1/3787
摘要： A system for monitoring and/or affecting parameters of a patient's body and more particularly to such a system comprised of a system control unit (SCU) and one or more other devices, preferably battery-powered, implanted in the patient's body, i.e., within the envelope defined by the patient's skin. Each such implanted device is configured to be monitored and/or controlled by the SCU via a wireless communication channel. In accordance with the invention, the SCU comprises a programmable unit capable of (1) transmitting commands to at least some of a plurality of implanted devices and (2) receiving data signal from at least some of those implanted devices. In accordance with a preferred embodiment, the system operates in closed loop fashion whereby the commands transmitted by the SCU are dependent, in part, on the content of the data signals received by the SCU.
摘要翻译： 一种用于监测和/或影响患者身体的参数的系统，更具体地涉及由系统控制单元（SCU）和一个或多个其它装置（优选由电池供电的）组成的系统，其被植入患者体内，即，在 由病人皮肤定义的信封。 每个这样的植入装置被配置为经由无线通信信道由SCU监视和/或控制。 根据本发明，SCU包括能够（1）向多个植入装置中的至少一些发送命令的可编程单元，以及（2）从至少某些植入装置接收数据信号。 根据优选实施例，系统以闭环方式操作，由此由SCU发送的命令部分地取决于由SCU接收的数据信号的内容。
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公开(公告)号：US20080294224A1
公开(公告)日：2008-11-27
申请号：US11926056
申请日：2007-10-28
IPC分类号： A61N1/04
CPC分类号： A61N1/0543 , A61N1/36046 , A61N1/37247 , A61N1/375 , H01L2224/16225 , Y10T29/49165
摘要： The present invention is a visual color prosthesis. The prosthesis creates the perception of a color image by electrically stimulating visual neurons in patterns consistent with the electrically patterns naturally produced by the retina in response to a color image.
摘要翻译： 本发明是视觉色假体。 假体通过以与视网膜自然产生的响应于彩色图像的电图案一致的图案电刺激视觉神经元而产生彩色图像的感知。
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