公开(公告)号：US07968119B2

公开(公告)日：2011-06-28

申请号：US10183678

申请日：2002-06-26

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： A61K9/20 ,  A61K9/48 ,  A61K9/14 ,  A61K9/16

CPC分类号： A61K45/06

摘要： A composition for oral, transdermal or subdermal administration to a subject is described. The composition contains: (a) an agonist component; (b) an antagonist component containing at least one antagonist and having a delayed time of release; and (c) an immediate release antagonist removal component, where the subject includes a gastrointestinal tract and the antagonist removal component is present in an amount sufficient to substantially remove the antagonist component from the gastrointestinal tract of the subject before the time of release of the antagonist component. The composition may be delivered to the subject by a method which includes the step of administering the composition orally, transdermally or subdermally to the subject. When the composition of the present invention is administered orally, the method of the present invention may include the step of administering a potassium compound to the subject.

摘要翻译： 描述了用于对受试者的口服，透皮或皮下给药的组合物。 组合物包含：（a）激动剂组分; （b）含有至少一种拮抗剂并具有延迟的释放时间的拮抗剂组分; 和（c）立即释放拮抗剂去除组分，其中受试者包括胃肠道，拮抗剂去除组分的存在量足以在释放拮抗剂之前从受试者的胃肠道基本上除去拮抗剂组分 零件。 组合物可以通过包括将组合物口服，经皮或皮下施用于受试者的步骤的方法递送至受试者。 当本发明的组合物口服给药时，本发明的方法可以包括向受试者施用钾化合物的步骤。

公开(公告)号：US4749536A

公开(公告)日：1988-06-07

申请号：US76030

申请日：1987-07-21

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C45/54 ,  B29C45/57 ,  B29C45/77

CPC分类号： B29C45/54 ,  B29C45/57

摘要： The present invention increases the shot capacity and the screw recovery time of an injection molding machine without increasing hydraulic pump capacity or motor horsepower. In accordance with one aspect of the invention, an existing injection molding machine is retrofitted with two cylinder and piston arrangements which are bolted onto the machine between its plasticizer barrel and its melt manifold. One of the cylinder and piston arrangements is employed to perform a mold-filling operation, whereas the other cylinder and piston arrangement is employed to perform packing and suck back operations.

摘要翻译： 本发明在不增加液压泵容量或马达功率的情况下提高注射成型机的喷射能力和螺杆恢复时间。 根据本发明的一个方面，现有的注塑机被改装有两个气缸和活塞装置，这两个气缸和活塞装置在其增塑剂筒和其熔体歧管之间螺栓连接在机器上。 使用气缸和活塞装置中的一个进行模具填充操作，而另一个气缸和活塞装置用于执行包装和回吸操作。

公开(公告)号：US4632652A

公开(公告)日：1986-12-30

申请号：US727683

申请日：1985-05-01

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C45/20 ,  B29C45/57 ,  B29C45/77

CPC分类号： B29C45/20 ,  B29C45/57

摘要： An injection molding apparatus including a barrel for holding molten plastic material, a first passage connected at one end with the barrel for receiving hot plastic material from the barrel, a second passage connected with the other end of the first passage for receiving molten material from the first passage for supplying the material to a mold, a cylinder, a third passage connected at one end with the cylinder and connected at its other end with the second passage, a piston in the cylinder, movable by pressure means in one direction to maintain pressure on molten material in the cylinder, the third passage and the second passage, and movable by pressure means in the other direction to exert a suction action in the cylinder, the third passage and the second passage for drawing molten material in the second passage back into the third passage and the cylinder, and a valve means. In such injection molding apparatus means for maintaining the valve means between in three positions including a restricted flow position is provided.In such injection molding apparatus means for controlling the pressure in the cylinder for at least one set point pressure is provided.

摘要翻译： 一种注射成型设备，包括用于保持熔融塑料材料的筒体，一端与筒体连接的第一通道，用于从筒体接收热塑性材料;第二通道，与第一通道的另一端连接，用于从 用于将材料供应到模具的第一通道，气缸，在一端与气缸连接并且在其另一端与第二通道连接的第三通道，气缸中的活塞，通过压力装置在一个方向上移动以保持压力 在气缸，第三通道和第二通道中的熔融材料上，并且可以通过压力装置在另一方向上移动，以在气缸中施加抽吸作用，第三通道和第二通道用于将第二通道中的熔融材料拉回 第三通道和气缸，以及阀装置。 在这种注射成型装置中，提供了用于将阀装置保持在包括受限流动位置的三个位置中的装置。 在这种注射成型装置中，提供了用于控制气缸中的压力至少一个设定点压力的装置。

公开(公告)号：US4038006A

公开(公告)日：1977-07-26

申请号：US641482

申请日：1975-12-17

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C49/06 ,  B29C49/16 ,  B29C49/48 ,  B29C49/50 ,  B29C49/58 ,  B29C17/07

CPC分类号： B29C49/50 ,  B29C49/16 ,  B29C49/4802 ,  B29C49/58 ,  B29C2049/4807 ,  B29C49/06 ,  B29L2031/463

摘要： A plastic container having a bail handle on one side, blown as one-piece with the container, is formed by injection molding a parison with a thickened portion then blow molding in a cavity having a portion into which the thickened portion of the parison is displaced to form a handle portion. A shearing operation is then performed on the partially blown container. In this operation part of the handle portion is compressed to a flat condition and displaced from the container between the body of the container and the part of the handle portion that will constitute the actual handle of the final container. The container is then blown to its final size, preferably in a second blowing mold. The apparatus used to make the container is also novel.

公开(公告)号：US3940223A

公开(公告)日：1976-02-24

申请号：US427333

申请日：1973-12-21

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C45/13 ,  B29C49/06 ,  B29F1/02 ,  B29F1/06

CPC分类号： B29C45/13 ,  B29C49/06

摘要： This invention reduces the time that a core rod must remain at an injection station of a plastic blow molding machine. The injection operation is usually performed by a plasticizer, and while the injection operation itself requires very little time, the plasticizer performs other roles that must be complete before the next injection. This invention uses two plasticizers alternately so that one can inject while the other recovers for its next injection operation. A plastic pump is used to relieve the plasticizers of some of the operations that they previously performed.

公开(公告)号：US4043735A

公开(公告)日：1977-08-23

申请号：US671054

申请日：1976-03-29

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C43/12 ,  B29C49/06 ,  B29C49/44 ,  B29C49/48 ,  B29C49/58 ,  B29C17/07

CPC分类号： B29C49/4823 ,  B29C49/06 ,  B29C49/44 ,  B29C49/58 ,  B29C43/12

摘要： This invention relates to blow molding apparatus for making plastic articles. It circulates cooling fluid through core rods for cooling blown articles from the inside, preferably with the blown article on the outside of a balloon that is permanently connected with the core rod. The connection of the balloon to the core rod is constructed so that there is no axial pull on the balloon during stripping of the blown article from the core rod and balloon. The invention provides constructions for admitting air between the balloon and a blown parison to break the vacuum when the balloon is to be collapsed. Fluid is also circulated over the outside of the blown parison to cool it, and this can be done in a perforated shroud that serves as a blowing mold, particularly for flexible wall containers.

摘要翻译： 本发明涉及制造塑料制品的吹塑设备。 它通过芯棒将冷却流体循环，用于从内部冷却吹塑制品，优选地将吹塑制品放置在与芯棒永久连接的气球的外侧上。 气囊与芯棒的连接被构造成使得吹塑制品从芯棒和球囊剥离时，气球上没有轴向拉动。 本发明提供了用于允许气囊和吹塑型坯之间的空气的构造，以在气囊被折叠时破坏真空。 流体也在吹塑型坯的外部循环，以使其冷却，这可以在用作吹塑模具的穿孔护罩中进行，特别是用于柔性壁容器。

公开(公告)号：US3981668A

公开(公告)日：1976-09-21

申请号：US545933

申请日：1975-01-31

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C43/12 ,  B29C49/12 ,  B29C49/44 ,  B29D23/03

CPC分类号： B29C49/44 ,  B29C49/12 ,  B29C43/12 ,  B29K2105/253 ,  Y10S425/015 ,  Y10S425/016

摘要： This injection blow molding machine has special provision for maintaining the plastic of a parison on a core rod at the orientation temperature of the plastic; and stretching the plastic of the parison lengthwise of the core rod for orientation in the direction of one axis without any substantial increase in the diameter of the parison. After this orientation in one axis, the temperature is controlled to maintain an orientation temperature, and the plastic of the parison is then blown to a larger diameter so as to obtain orientation in another axis for bi-axial orientation. The core rod is covered by an elastic balloon, and provision is made for obtaining flow of the plastic on the core rod lengthwise of the rod during the first orientation operation.

摘要翻译： 该注射吹塑机具有在塑料的取向温度下保持芯棒上型坯的塑料的特殊规定; 并且将长条状的芯棒的塑料沿着一个轴线的方向拉伸，以使型坯的直径不会明显增加。 在一个轴的该取向之后，控制温度以保持取向温度，然后将型坯的塑料吹至更大的直径，以获得另一个轴线的双轴取向的取向。 芯棒被弹性气球覆盖，并且在第一取向操作期间提供用于在杆的纵向上获得芯棒上的塑料的流动。

公开(公告)号：US3955908A

公开(公告)日：1976-05-11

申请号：US419510

申请日：1973-11-28

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C43/12 ,  B29C49/06 ,  B29C49/44 ,  B29C49/48 ,  B29C49/58 ,  B29D23/03

CPC分类号： B29C49/06 ,  B29C49/44 ,  B29C49/4823 ,  B29C49/58 ,  B29C43/12

摘要： This invention relates to blow molding apparatus for making plastic articles. It circulates cooling fluid through core rods for cooling blown articles from the inside, preferably with the blown article on the outside of a balloon that is permanently connected with the core rod. The connection of the balloon to the core rod is constructed so that there is no axial pull on the balloon during stripping of the blown article from the core rod and balloon. The invention provides constructions for admitting air between the balloon and a blown parison to break the vacuum when the balloon is to be collapsed. Fluid is also circulated over the outside of the blown parison to cool it, and this can be done in a perforated shroud that serves as a blowing mold, particularly for flexible wall containers.

摘要翻译： 本发明涉及制造塑料制品的吹塑设备。 它通过芯棒将冷却流体循环，用于从内部冷却吹塑制品，优选地将吹塑制品放置在与芯棒永久连接的气球的外侧上。 气囊与芯棒的连接被构造成使得吹塑制品从芯棒和球囊剥离时，气球上没有轴向拉动。 本发明提供了用于允许气囊和吹塑型坯之间的空气的构造，以在气囊被折叠时破坏真空。 流体也在吹塑型坯的外部循环，以使其冷却，这可以在用作吹塑模具的穿孔护罩中进行，特别是用于柔性壁容器。

公开(公告)号：US3936260A

公开(公告)日：1976-02-03

申请号：US512294

申请日：1974-10-04

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C49/06 ,  B29C49/16 ,  B29D23/02 ,  B29D23/03

CPC分类号： B29C49/16 ,  B29C49/06 ,  B29C2049/4858

摘要： This invention increases the length-to-diameter ratio of plastic articles made on injection molding machines without using long and relatively thin core rods. This added length is obtained by having the first part of the blowing operation stretch the parison lengthwise before there is any substantial displacement of the parison in a radial direction. At the start of the blowing operation, a tube surrounds and confines radial expansion of the parison, but this tube is withdrawn progressively as the blowing operation continues.

摘要翻译： 本发明增加了在注射成型机上制造的塑料制品的长径比，而不使用长且相对薄的芯棒。 通过使吹塑操作的第一部分在型坯在径向方向上的任何实际位移之前纵向拉伸型坯，可以获得增加的长度。 在吹塑操作开始时，管围绕并限制型坯的径向膨胀，但是随着吹塑操作的持续，该管逐渐抽出。

公开(公告)号：US3930779A

公开(公告)日：1976-01-06

申请号：US433578

申请日：1974-01-15

申请人： John J. Farrell

发明人： John J. Farrell

IPC分类号： B29C35/16 ,  B29C49/48 ,  B29C49/64 ,  B29D23/02 ,  B29D23/03

CPC分类号： B29C49/4823 ,  B29C49/6463 ,  B29C2049/4676 ,  B29C2791/005 ,  B29C35/16

摘要： This invention cools the blowing mold and the plastic article blown therein to shorten the time that a core rod must remain at a blowing station of a blow molding machine for making plastic articles. The cooling is performed by conditioned air that is dried to lower its dew point. An air curtain is used to prevent other air from contacting with and depositing moisture on the mold. In order to take advantage of the shorter time at the blowing station, an auxiliary injection device is used to also shorten the time required for the injection operation; and auxiliary cooling is supplied to the core rod at the stripper station.