公开(公告)号：US08592402B2

公开(公告)日：2013-11-26

申请号：US13388502

申请日：2010-08-03

申请人： John Howard Hutchinson ,  Thomas J. Seiders ,  Wang Bowei

发明人： John Howard Hutchinson ,  Thomas J. Seiders ,  Wang Bowei

IPC分类号： A61K31/56 ,  A61K31/42 ,  C07D261/14

CPC分类号： C07D261/14 ,  A61K31/42 ,  A61K31/4427 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D413/14 ,  C07D417/04 ,  C07F9/653

摘要： Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.