公开(公告)号：US09434711B2

公开(公告)日：2016-09-06

申请号：US14322554

申请日：2014-07-02

申请人： Janssen Pharmaceutica, NV

发明人： Shawn T Branum ,  Raymond W Colburn ,  Scott L Dax ,  Christopher M Flores ,  Michele C Jetter ,  Yi Liu ,  Donald Ludovici ,  Mark J Macielag ,  Jay M Matthews ,  James J McNally ,  Laura M Andraka ,  Ronald K Russell ,  Ning Qin ,  Christopher Teleha ,  Kenneth M Wells ,  Scott C Youells ,  Mark A Youngman

IPC分类号： A61K31/381 ,  A61K31/541 ,  A61K31/4709 ,  A61K31/5377 ,  A61P29/02 ,  C07D333/66 ,  C07D333/36 ,  C07D495/04 ,  C07D409/12 ,  C07D409/14 ,  C07D417/12

CPC分类号： C07D333/66 ,  C07D333/36 ,  C07D409/12 ,  C07D409/14 ,  C07D417/12 ,  C07D495/04

摘要： Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein A, B, G, Y, R1, R2, R3, and R4 are defined herein.