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公开(公告)号：US09206248B2
公开(公告)日：2015-12-08
申请号：US14617003
申请日：2015-02-09
Applicant: Janssen Biotech, Inc.
Inventor： Jill Carton , Jin Lu , Bernard Scallon , Linda Snyder
CPC classification number: C07K16/00 , C07K2317/14 , C07K2317/56 , C07K2319/036 , C12N15/85 , C12N2800/22
Abstract: Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.
Abstract translation: 抗体表达载体和质粒可以掺入用于转录抗体DNA的各种抗体基因部分和抗体在合适的宿主细胞中的表达。 表达载体和质粒具有有利于将抗体编码DNA连接到载体中的限制酶位点。 载体包含增强子和启动子序列，其可以变化以与宿主细胞中的转录因子相互作用，从而控制抗体编码DNA的转录。 试剂盒可以并入这些载体和质粒。
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公开(公告)号：US20150147805A1
公开(公告)日：2015-05-28
申请号：US14617003
申请日：2015-02-09
Applicant: Janssen Biotech, Inc.
Inventor： Jill Carton , Jin Lu , Bernard Scallon , Linda Snyder
CPC classification number: C07K16/00 , C07K2317/14 , C07K2317/56 , C07K2319/036 , C12N15/85 , C12N2800/22
Abstract: Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.
Abstract translation: 抗体表达载体和质粒可以掺入用于转录抗体DNA的各种抗体基因部分和抗体在合适的宿主细胞中的表达。 表达载体和质粒具有有利于将抗体编码DNA连接到载体中的限制酶位点。 载体包含增强子和启动子序列，其可以变化以与宿主细胞中的转录因子相互作用，从而控制抗体编码DNA的转录。 试剂盒可以并入这些载体和质粒。
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公开(公告)号：US08980626B2
公开(公告)日：2015-03-17
申请号：US14163469
申请日：2014-01-24
Applicant: Janssen Biotech, Inc.
Inventor： Jill Carton , Jin Lu , Bernard Scallon , Linda Snyder
CPC classification number: C07K16/00 , C07K2317/14 , C07K2317/56 , C07K2319/036 , C12N15/85 , C12N2800/22
Abstract: Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.
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公开(公告)号：US20140141506A1
公开(公告)日：2014-05-22
申请号：US14163469
申请日：2014-01-24
Applicant: Janssen Biotech, Inc.
Inventor： Jill Carton , Jin Lu , Bernard Scallon , Linda Snyder
IPC: C07K16/00
CPC classification number: C07K16/00 , C07K2317/14 , C07K2317/56 , C07K2319/036 , C12N15/85 , C12N2800/22
Abstract: Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.
Abstract translation: 抗体表达载体和质粒可以掺入用于转录抗体DNA的各种抗体基因部分和抗体在合适的宿主细胞中的表达。 表达载体和质粒具有有利于将抗体编码DNA连接到载体中的限制酶位点。 载体包含增强子和启动子序列，其可以变化以与宿主细胞中的转录因子相互作用，从而控制抗体编码DNA的转录。 试剂盒可以并入这些载体和质粒。
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