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公开(公告)号：US20180148476A1
公开(公告)日：2018-05-31
申请号：US15570838
申请日：2016-04-29
CPC分类号： C07K7/08 , A61K9/0031 , A61K9/0053 , A61K38/00 , A61K38/10 , A61K38/12 , A61K45/06 , A61P1/10 , A61P35/00
摘要： The present invention provides peptides and compositions that are useful for the treatment of gastrointestinal disorders or for colon cleansing. The present invention also provides compositions and methods of treating gastrointestinal disorders and pharmaceutical compositions for accomplishing the same. In some embodiments, these pharmaceutical compositions include oral dosage forms.
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公开(公告)号：US20210032292A1
公开(公告)日：2021-02-04
申请号：US17066802
申请日：2020-10-09
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein. using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
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公开(公告)号：US20230272007A1
公开(公告)日：2023-08-31
申请号：US18143892
申请日：2023-05-05
CPC分类号： C07K7/08 , C11D3/3436 , C07K7/54 , C07K5/02 , A61K38/10 , A61K38/12 , A61K45/06 , G01N2800/065 , Y02A50/30
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein. using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
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公开(公告)号：US20190062376A1
公开(公告)日：2019-02-28
申请号：US16171524
申请日：2018-10-26
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein. using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
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公开(公告)号：US20240199697A1
公开(公告)日：2024-06-20
申请号：US18424114
申请日：2024-01-26
CPC分类号： C07K7/08 , A61K9/0031 , A61K9/0053 , A61K38/10 , A61K38/12 , A61K45/06 , A61P1/10 , A61P35/00 , A61K38/00
摘要： The present invention provides peptides and compositions that are useful for the treatment of gastrointestinal disorders or for colon cleansing. The present invention also provides compositions and methods of treating gastrointestinal disorders and pharmaceutical compositions for accomplishing the same. In some embodiments, these pharmaceutical compositions include oral dosage forms.
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公开(公告)号：US20220119452A1
公开(公告)日：2022-04-21
申请号：US17566241
申请日：2021-12-30
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein. using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
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公开(公告)号：US20180186835A1
公开(公告)日：2018-07-05
申请号：US15906744
申请日：2018-02-27
CPC分类号： C07K7/08 , A61K38/10 , A61K38/12 , A61K45/06 , C07K5/02 , C07K7/54 , C11D3/3436 , G01N2800/065 , Y02A50/414
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein. using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
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