公开(公告)号：US10143198B2

公开(公告)日：2018-12-04

申请号：US15713840

申请日：2017-09-25

申请人： Investfood, LLC

发明人： Cristina Núñez Lechado ,  Alberto Baños Arjona ,  Enrique Guillamón Ayala ,  Adela Valero López ,  Ma Concepción Navarro Moll ,  Ana Sanz Rus

IPC分类号： A61K31/255 ,  A01N41/02 ,  A23K20/10 ,  A23K50/80 ,  A01N41/08 ,  A61K9/00 ,  A61K47/02 ,  A61K9/08

摘要： A method for reducing parasites in aquatic animals is provided. The method includes administering to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2 and also propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1, so that a combination of PTS and PTSO is administered to the aquatic animal resulting in the reduction of a plurality of crustaceans infecting the aquatic animal in response to administering the combination of PTS and PTSO to the aquatic animal.

公开(公告)号：US20180014538A1

公开(公告)日：2018-01-18

申请号：US15713840

申请日：2017-09-25

申请人： Investfood, LLC

发明人： Cristina Núñez Lechado ,  Alberto Baños Arjona ,  Enrique Guillamón Ayala ,  Adela Valero López ,  Mª Concepción Navarro Moll ,  Ana Sanz Rus

IPC分类号： A01N41/02 ,  A01N41/08 ,  A61K31/255 ,  A61K9/00 ,  A61K9/08 ,  A61K47/02

CPC分类号： A01N41/02 ,  A01N41/08 ,  A23K20/10 ,  A23K50/80 ,  A61K9/0014 ,  A61K9/08 ,  A61K31/255 ,  A61K47/02 ,  A61K2300/00

摘要： A method for reducing parasites in aquatic animals is provided. The method includes administering to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2 and also propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1, so that a combination of PTS and PTSO is administered to the aquatic animal resulting in the reduction of a plurality of crustaceans infecting the aquatic animal in response to administering the combination of PTS and PTSO to the aquatic animal.

公开(公告)号：US09271947B2

公开(公告)日：2016-03-01

申请号：US14043160

申请日：2013-10-01

申请人： Investfood, LLC

发明人： Cristina Núñez Lechado ,  Alberto Baños Arjona ,  Enrique Guillamón Ayala ,  Adela Valero López ,  Ma Concepción Navarro Moll ,  Ana Sanz Rus

IPC分类号： A61K31/105 ,  A61K31/10 ,  A01N41/10 ,  A23K1/18 ,  A23K1/16 ,  A61K31/255

CPC分类号： A61K31/10 ,  A01N41/10 ,  A23K20/10 ,  A23K50/80 ,  A61K31/255 ,  A61K2300/00

摘要： A method for reducing parasites in aquatic animals is provided. The method includes reducing a plurality of parasites infecting an aquatic animal by administrating to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2. In yet a different embodiment, a method for reducing a plurality of parasites infecting an aquatic animal includes administrating to the aquatic animal a compound comprising and propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1. In even yet another embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTS. In a different embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTSO.

摘要翻译： 提供了一种减少水生动物寄生虫的方法。 该方法包括通过向水生动物施用包含具有式R-SO-S-R的丙基硫代磺酸丙酯（PTSO）的化合物来减少感染水生动物的多种寄生虫，其中R表示正丙基（-CH 2 -CH 2 -CH 3）和a为2.在另一个不同的实施方案中，减少感染水生动物的多种寄生虫的方法包括向水生动物施用包含具有式R-SOa-S的丙烷次硫酸亚丙酯（PTS）的化合物 -R，其中R表示正丙基（-CH 2 -CH 2 -CH 3），a为1.在另一个实施方案中，提供了防止水生动物中多种寄生虫的方法，包括向水生动物施用 化合物包括PTS。 在不同的实施方案中，提供了一种用于在水生动物中预防多种寄生虫的方法，包括向水生动物施用包括PTSO的化合物。

公开(公告)号：US20150094381A1

公开(公告)日：2015-04-02

申请号：US14043160

申请日：2013-10-01

申请人： Investfood, LLC

发明人： Cristina Núñez Lechado ,  Alberto Baños Arjona ,  Enrique Guillamón Ayala ,  Adela Valero López ,  Mª Concepción Navarro Moll ,  Ana Sanz Rus

IPC分类号： A61K31/10

CPC分类号： A61K31/10 ,  A01N41/10 ,  A23K20/10 ,  A23K50/80 ,  A61K31/255 ,  A61K2300/00

摘要： A method for reducing parasites in aquatic animals is provided. The method includes reducing a plurality of parasites infecting an aquatic animal by administrating to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2. In yet a different embodiment, a method for reducing a plurality of parasites infecting an aquatic animal includes administrating to the aquatic animal a compound comprising and propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1. In even yet another embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTS. In a different embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTSO.

摘要翻译： 提供了一种减少水生动物寄生虫的方法。 该方法包括通过向水生动物施用包含具有式R-SO-S-R的丙基硫代磺酸丙酯（PTSO）的化合物来减少感染水生动物的多种寄生虫，其中R表示正丙基（-CH 2 -CH 2 -CH 3）和a为2.在另一个不同的实施方案中，减少感染水生动物的多种寄生虫的方法包括向水生动物施用包含具有式R-SOa-S的丙烷次硫酸亚丙酯（PTS）的化合物 -R，其中R表示正丙基（-CH 2 -CH 2 -CH 3），a为1.在另一个实施方案中，提供了防止水生动物中多种寄生虫的方法，包括向水生动物施用 化合物包括PTS。 在不同的实施方案中，提供了一种用于在水生动物中预防多种寄生虫的方法，包括向水生动物施用包括PTSO的化合物。

公开(公告)号：US09770024B2

公开(公告)日：2017-09-26

申请号：US15056695

申请日：2016-02-29

申请人： Investfood, LLC

发明人： Cristina Núñez Lechado ,  Alberto Baños Arjona ,  Enrique Guillamón Ayala ,  Adela Valero López ,  Ma Concepción Navarro Moll ,  Ana Sanz Rus

IPC分类号： A61K31/105 ,  A01N41/02 ,  A61K31/255 ,  A23K20/10 ,  A23K50/80 ,  A01N41/08 ,  A61K9/00 ,  A61K47/02 ,  A61K9/08

CPC分类号： A01N41/02 ,  A01N41/08 ,  A23K20/10 ,  A23K50/80 ,  A61K9/0014 ,  A61K9/08 ,  A61K31/255 ,  A61K47/02 ,  A61K2300/00

摘要： A method for reducing parasites in aquatic animals is provided. The method includes administering to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2 and also propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1, so that a combination of PTS and PTSO is administered to the aquatic animal resulting in the reduction of a plurality of crustaceans infecting the aquatic animal in response to administering the combination of PTS and PTSO to the aquatic animal.

公开(公告)号：US20160205930A1

公开(公告)日：2016-07-21

申请号：US15056695

申请日：2016-02-29

申请人： Investfood, LLC

发明人： Cristina Núñez Lechado ,  Alberto Baños Arjona ,  Enrique Guillamón Ayala ,  Adela Valero López ,  Mª Concepción Navarro Moll ,  Ana Sanz Rus

IPC分类号： A01N41/02 ,  A01N41/04

CPC分类号： A01N41/02 ,  A01N41/08 ,  A23K20/10 ,  A23K50/80 ,  A61K9/0014 ,  A61K9/08 ,  A61K31/255 ,  A61K47/02 ,  A61K2300/00

摘要： A method for reducing parasites in aquatic animals is provided. The method includes administering to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2 and also propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1, so that a combination of PTS and PTSO is administered to the aquatic animal resulting in the reduction of a plurality of crustaceans infecting the aquatic animal in response to administering the combination of PTS and PTSO to the aquatic animal.

摘要翻译： 提供了一种减少水生动物寄生虫的方法。 该方法包括向水生动物施用包含具有式R-SOa-S-R的丙基丙磺酸盐（PTSO）的化合物，其中R表示正丙基（-CH 2 -CH 2 -CH 3），a为2，并且丙基 具有式R-SOa-S-R的丙烷硫代亚磺酸酯（PTS），其中R表示正丙基（-CH 2 -CH 2 -CH 3），a为1，从而向水生动物施用PTS和PTSO的组合 导致响应于向水生动物施用PTS和PTSO的组合而导致感染水生动物的多个甲壳类动物的减少。

公开(公告)号：US20150238579A1

公开(公告)日：2015-08-27

申请号：US14191158

申请日：2014-02-26

申请人： INVESTFOOD, LLC

发明人： Alberto Baños Arjona ,  Julio J. Gálvez Peralta ,  Enrique Guillamón Ayala ,  Cristina Núñez Lechado ,  Francisco Maroto Caba ,  Maria Elena Rodriquez Cabezas

IPC分类号： A61K39/00 ,  A23L2/52 ,  A23L1/30

CPC分类号： A23L2/52 ,  A23L33/10 ,  A61K39/39 ,  A61K2039/55511

摘要： Embodiments of the invention provide a method for assembling a propyl propane thiosulfonate (PTSO) product for modulating immune function in healthy and sick humans. The method includes selecting a PTSO based compound for incorporation into a PTSO product. The PTSO based compound includes PTSO having a formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2. The PTSO based compound is then incorporated into a PTSO product.

摘要翻译： 本发明的实施方案提供了用于在健康和病态人体中调节免疫功能的丙基硫代磺酸丙酯（PTSO）产品的组装方法。 该方法包括选择用于掺入PTSO产物的基于PTSO的化合物。 基于PTSO的化合物包括具有式R-SOa-S-R的PTSO，其中R表示正丙基（-CH 2 -CH 2 -CH 3），a为2.然后将PTSO基化合物掺入PTSO产物中。