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公开(公告)号：US20180318265A1
公开(公告)日：2018-11-08
申请号：US15944967
申请日：2018-04-04
Applicant: Intervet Inc.
Inventor： Heike Williams , Anja Regina Heckeroth , Janina Tanzler , Regis Joel Alain Frenais
IPC: A61K31/42 , A61K9/20 , A61K9/00 , A61K31/422
Abstract: The present invention relates to methods of treating demodicosis by administering an isoxazoline compound of formula (I)
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公开(公告)号：US20170348286A1
公开(公告)日：2017-12-07
申请号：US15537547
申请日：2015-12-21
Applicant: Intervet Inc.
Inventor： Heike Williams , Anja Regina Heckeroth , Janina Tanzler , Regis Joel Alain Frenais
IPC: A61K31/42 , A61K9/20 , A61K9/00 , A61K31/422
CPC classification number: A61K31/42 , A61K9/0014 , A61K9/0019 , A61K9/0053 , A61K9/0056 , A61K9/20 , A61K31/422
Abstract: The present invention relates to methods of treating demodicosis by administering an isoxazoline compound of formula (I).
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公开(公告)号：US20240239759A1
公开(公告)日：2024-07-18
申请号：US18416336
申请日：2024-01-18
Applicant: Intervet Inc.
Inventor： Anja Regina Heckeroth , Jürgen Lutz , Christina Mertens , Heike Williams , Hartmut Zoller , Takeshi Mita
IPC: C07D261/04 , A01N43/80 , A01N47/12 , A01N47/18 , A01N53/00 , A61K31/42 , C07D413/12 , C07D417/12
CPC classification number: C07D261/04 , A01N43/80 , A01N47/12 , A01N47/18 , A01N53/00 , A61K31/42 , C07D413/12 , C07D417/12 , Y02A50/30
Abstract: This invention relates to methods for controlling parasitic infestations of animals and their environments, and, more particularly, to methods using isoxazolines to control parasites in or on animals or in their environments, as well as treat parasitoses of animals. The isoxazolines include 4-(isoxazolinyl)-benzamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzamides) and 4-(isoxazolinyl)-benzothioamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzothioamides). This invention also relates to compositions comprising the isoxazolines for use in such methods, the use of the isoxazolines to make medicaments for use in such methods, and kits comprising the isoxazolines for carrying out such methods. This invention further relates to the use of the isoxazolines as medicaments, particularly medicaments that can be used in the above-referenced method.
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公开(公告)号：US09655884B2
公开(公告)日：2017-05-23
申请号：US15101430
申请日：2014-12-09
Applicant: Intervet Inc.
Inventor： Heike Williams , Hartmut Zoller , Anja Regina Heckeroth
IPC: A61K31/42 , A01N43/80 , C07D403/10 , C07D471/04 , C07D261/08 , A61K9/00
CPC classification number: A61K31/42 , A01N43/80 , A61K9/0053 , C07D261/08 , C07D403/10 , C07D471/04
Abstract: This invention relates to methods for preventing infestations of animals and their environments with adult fleas by systemic administration of isoxazoline compounds.
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公开(公告)号：US20170071914A1
公开(公告)日：2017-03-16
申请号：US15359036
申请日：2016-11-22
Applicant: Intervet Inc.
Inventor： Stefan Fuchs , Anja Regina Heckeroth , Ramona Müller , Heike Williams , Hartmut Zoller
IPC: A61K31/42 , A61K47/20 , A61K47/22 , A61K47/10 , A61K47/18 , A61K31/366 , A61K47/08 , A61K9/00 , A61K47/12
CPC classification number: A61K31/42 , A01N43/80 , A61K9/0014 , A61K9/0017 , A61K31/366 , A61K45/06 , A61K47/08 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/22 , A61P33/14 , A01N25/02 , A01N37/18 , A01N2300/00
Abstract: This invention provides topical localized formulations comprising an isoxazoline compound and a pharmaceutically or veterinary acceptable liquid carrier vehicle comprising N,N-diethyl-3-methylbenzamide as a solvent and an improved method for controlling, and preventing parasite infestation in animals.
Abstract translation: 本发明提供了包含异恶唑啉化合物和包含N，N-二乙基-3-甲基苯甲酰胺作为溶剂的药学上或兽医学上可接受的液体载体载体的局部局部制剂，以及用于控制和预防动物中寄生虫侵染的改进方法。
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Patent Agency Ranking
公开(公告)号：US20180085352A1
公开(公告)日：2018-03-29
申请号：US15819523
申请日：2017-11-21
Applicant: Intervet Inc.
Inventor： Stefan Fuchs , Anja Regina Heckeroth , Ramona Müller , Heike Williams , Hartmut Zoller
IPC: A61K31/42 , A61K9/00 , A61K31/366 , A61K47/08 , A61K47/12 , A61K47/18 , A61K47/20 , A61K47/10 , A61K47/22 , A01N43/80 , A61K45/06 , A01N25/02 , A01N37/18
CPC classification number: A61K31/42 , A01N43/80 , A61K9/0014 , A61K9/0017 , A61K31/366 , A61K45/06 , A61K47/08 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/22 , A61P33/14 , A01N25/02 , A01N37/18 , A01N2300/00
Abstract: This invention provides topical localized formulations comprising an isoxazoline compound and a pharmaceutically or veterinary acceptable liquid carrier vehicle comprising N,N-diethyl-3-methylbenzamide as a solvent and an improved method for controlling, and preventing parasite infestation in animals.
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公开(公告)号：US20160332975A1
公开(公告)日：2016-11-17
申请号：US15222171
申请日：2016-07-28
Applicant: Intervet Inc.
Inventor： Anja Regina Heckeroth , Jürgen Lutz , Christina Mertens , Heike Williams , Hartmut Zoller , Takeshi Mita
IPC: C07D261/04 , C07D417/12 , C07D413/12 , A01N43/80
CPC classification number: C07D261/04 , A01N43/80 , A01N47/12 , A01N47/18 , A01N53/00 , A61K31/42 , C07D413/12 , C07D417/12 , Y02A50/401 , Y02A50/402
Abstract: This invention relates to methods for controlling parasitic infestations of animals and their environments, and, more particularly, to methods using isoxazolines to control parasites in or on animals or in their environments, as well as treat parasitoses of animals. The isoxazolines include 4-(isoxazolinyl)-benzamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzamides) and 4-(isoxazolinyl)-benzothioamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzothioamides). This invention also relates to compositions comprising the isoxazolines for use in such methods, the use of the isoxazolines to make medicaments for use in such methods, and kits comprising the isoxazolines for carrying out such methods. This invention further relates to the use of the isoxazolines as medicaments, particularly medicaments that can be used in the above-referenced method.
Abstract translation: 本发明涉及用于控制动物及其环境的寄生虫感染的方法，更具体地，涉及使用异恶唑啉来控制动物或其环境中或动物或其环境中的寄生虫以及治疗动物寄生虫的方法。 异恶唑啉包括4-（异恶唑啉基） - 苯甲酰胺（具体地，取代的4-（5-（卤代甲基）-5-苯基 - 异恶唑啉-3-基） - 苯甲酰胺）和4-（异恶唑啉基） - 苯并硫代酰胺（具体地， （5-（卤代甲基）-5-苯基 - 异恶唑啉-3-基） - 苯并硫代酰胺）。 本发明还涉及包含用于此类方法的异恶唑烷的组合物，异恶唑啉用于制备用于此类方法的药物的用途，以及包含用于进行此类方法的异恶唑啉的试剂盒。 本发明还涉及异恶唑啉作为药物的用途，特别是可以在上述方法中使用的药物。
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公开(公告)号：US20160303086A1
公开(公告)日：2016-10-20
申请号：US15101430
申请日：2014-12-09
Applicant: INTERVET INTERNATIONAL B.V. , INTERVET INC.
Inventor： Heike Williams , Hartmut Zoller , Anja Regina Heckeroth
CPC classification number: A61K31/42 , A01N43/80 , A61K9/0053 , C07D261/08 , C07D403/10 , C07D471/04
Abstract: This invention relates to methods for preventing infestations of animals and their environments with adult fleas by systemic administration of isoxazoline compounds.
Abstract translation: 本发明涉及通过全身给予异恶唑啉化合物来预防动物及其成年蚤的环境侵袭的方法。
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公开(公告)号：US20210061775A1
公开(公告)日：2021-03-04
申请号：US17021698
申请日：2020-09-15
Applicant: Intervet Inc.
Inventor： Anja Regina Heckeroth , Jürgen Lutz , Christina Mertens , Heike Williams , Hartmut Zoller , Takeshi Mita
IPC: C07D261/04 , A01N43/80 , A01N47/12 , A01N47/18 , A01N53/00 , A61K31/42 , C07D413/12 , C07D417/12
Abstract: This invention relates to methods for controlling parasitic infestations of animals and their environments, and, more particularly, to methods using isoxazolines to control parasites in or on animals or in their environments, as well as treat parasitoses of animals. The isoxazolines include 4-(isoxazolinyl)-benzamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzamides) and 4-(isoxazolinyl)-benzothioamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzothioamides). This invention also relates to compositions comprising the isoxazolines for use in such methods, the use of the isoxazolines to make medicaments for use in such methods, and kits comprising the isoxazolines for carrying out such methods. This invention further relates to the use of the isoxazolines as medicaments, particularly medicaments that can be used in the above-referenced method.
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公开(公告)号：US20180155301A1
公开(公告)日：2018-06-07
申请号：US15880770
申请日：2018-01-26
Applicant: Intervet Inc.
Inventor： Anja Regina Heckeroth , Jürgen Lutz , Christina Mertens , Heike Williams , Hartmut Zoller , Takeshi Mita
IPC: C07D261/04 , C07D417/12 , C07D413/12 , A01N43/80 , A01N53/00 , A01N47/18 , A01N47/12 , A61K31/42
CPC classification number: C07D261/04 , A01N43/80 , A01N47/12 , A01N47/18 , A01N53/00 , A61K31/42 , C07D413/12 , C07D417/12 , Y02A50/401 , Y02A50/402
Abstract: This invention relates to methods for controlling parasitic infestations of animals and their environments, and, more particularly, to methods using isoxazolines to control parasites in or on animals or in their environments, as well as treat parasitoses of animals. The isoxazolines include 4-(isoxazolinyl)-benzamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzamides) and 4-(isoxazolinyl)-benzothioamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzothioamides). This invention also relates to compositions comprising the isoxazolines for use in such methods, the use of the isoxazolines to make medicaments for use in such methods, and kits comprising the isoxazolines for carrying out such methods. This invention further relates to the use of the isoxazolines as medicaments, particularly medicaments that can be used in the above-referenced method.
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