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公开(公告)号：US11067568B2
公开(公告)日：2021-07-20
申请号：US15096175
申请日：2016-04-11
IPC分类号： G01N33/543 , G01N27/74 , B82Y15/00
摘要： Described are embodiments of an invention for detecting target antigens in a biological sample using a sample assembly. Detection may be accomplished by performing a method comprising: sweeping a head module over the sample assembly, wherein said head module includes at least one magneto-resistive read sensor configured to detect target antigens via nanoparticles within the sample assembly; and detecting at least one particular antigen among the target antigens. Preferably, detecting the target antigens via the nanoparticles is based at least in part on detecting unique magnetic properties of particular nanoparticles specifically associated with different types of the target antigens. Detection using a magnetic read/write head in the sample assembly facilitates automation of sample detection with high speed and fidelity. Corresponding systems are also disclosed.
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公开(公告)号：US11045552B2
公开(公告)日：2021-06-29
申请号：US15479071
申请日：2017-04-04
申请人： International Business Machines Corporation , Agency for Science, Technology and Research (ASTAR)
发明人： Dylan J. Boday , Jeannette M. Garcia , James L. Hedrick , Nathaniel H. Park , Rudy J. Wojtecki , Yang Chuan , Ashlynn Lee , Zhen Chang Liang , Shaoqiong Liu , Yi Yan Yang
摘要： A stimulus-responsive micellar carrier, methods that may be associated with making a stimulus-responsive micellar carrier, and methods that may be associated with using a stimulus-responsive micellar carrier are disclosed. The stimulus-responsive micellar carrier comprises a cargo molecule, and a linear block copolymer having a hydrophilic block connected to a hydrophobic block by a stimulus-responsive junction moiety. The micellar carrier can be supplied to a patient body for therapeutic purposes, such as the treatment of cancerous tissue. A method of preparing or obtaining a stimulus-responsive micellar carrier may include preparing a polyethylene glycol material having an acetal end group and then preparing a block copolymer by forming a reaction mixture including the polyethylene glycol material, a cyclic carbonate monomer, and a base.
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公开(公告)号：US10968320B2
公开(公告)日：2021-04-06
申请号：US16238735
申请日：2019-01-03
IPC分类号： C09K5/00 , C08G81/02 , H01L23/373 , H01L23/427 , C08F299/04 , C08G63/676 , H01L23/00 , C08G65/332 , C09K5/02 , C09K5/06
摘要： In an example, a thermal interface material includes a polymeric phase-change material.
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4.发明授权公开(公告)号：US10828883B2
公开(公告)日：2020-11-10
申请号：US16357037
申请日：2019-03-18
IPC分类号： B29C67/00 , C09D4/06 , C09D133/14 , B33Y70/00 , B33Y10/00 , B33Y30/00 , C09D11/106 , C09D11/30 , B29C64/112 , B81B1/00 , B33Y50/02
摘要： Thermally cross-linkable photo-hydrolyzable inkjet printable polymers are used to print microfluidic channels layer-by-layer on a substrate. In one embodiment, for each layer, an inkjet head deposits droplets of a mixture of hydrophobic polymer and cross-linking agent in a pattern lying outside a two-dimensional layout of the channels, and another inkjet head deposits droplets of a mixture of poly(tetrahydropyranyl methacrylate) PTHPMA (or another hydrophobic polymer which hydrolyzes to form a hydrophilic material), cross-linking agent, and a photoacid generator (PAG) in a pattern lying inside the two-dimensional layout of the channels. After all layers are printed, flood exposure of the entire substrate to UV radiation releases acid from the PAG which hydrolyzes PTHPMA to form hydrophilic poly(methacrylic acid) PMAA, thereby rendering the PTHPMA regions hydrophilic. The layers of these now-hydrophilic patterned regions together define the microfluidic channels. The cross-linking agent (e.g., triallyl isocyanurate TAIC) forms covalent cross-links between the two polymer phases.
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公开(公告)号：US10566029B2
公开(公告)日：2020-02-18
申请号：US15801146
申请日：2017-11-01
发明人： Dylan J. Boday , Andrew S. Green , Shawn M. Nave
摘要： A method according to one embodiment includes inserting a data storage cartridge into an opening in a housing, the housing having a retention tab in the housing for engaging with a notch of the data storage cartridge for retaining the data storage cartridge in the housing. The retention tab has a texture. The texture of the retention tab is configured to reduce a force necessary for removing the data storage cartridge from the housing.
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公开(公告)号：US10557008B2
公开(公告)日：2020-02-11
申请号：US15815200
申请日：2017-11-16
摘要： A porous material includes a resin material based on a trifunctional ethynyl monomer. Pores in the porous material can be of various sizes including nanoscale sizes. The porous material may be used in a variety of applications, such as those requiring materials with a high strength-to-weight ratio. The porous material can include a filler material dispersed therein. The filler material can be, for example, a particle, a fiber, a fabric, or the like. In some examples, the filler material can be a carbon fiber or a carbon nanotube. A method of making a porous material includes forming a resin including a trifunctional ethynyl monomer component and a polythioaminal component. The resin can be heated to promote segregation of the components into different phases with predominately one or the other component in each phase. Processing of the resin after phase segregation to decompose the polythioaminal component can form pores in the resin.
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公开(公告)号：US10428198B2
公开(公告)日：2019-10-01
申请号：US15008256
申请日：2016-01-27
发明人： Dylan J. Boday , Joseph Kuczynski , Jason T. Wertz , Jing Zhang
IPC分类号： C08K3/36 , C09D5/32 , C09J201/00 , C09D201/00 , C08K9/06 , C09D7/62
摘要： In an example, a silica particle includes a light stabilizer material and is matrix-modified to include an ultraviolet (UV) light absorbing material.
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公开(公告)号：US20190218342A1
公开(公告)日：2019-07-18
申请号：US16362275
申请日：2019-03-22
CPC分类号： C08G73/0644 , C08G12/08 , C08G73/065 , G03F7/038 , G03F7/20 , G03F7/30
摘要： This disclosure describes new compositions and methods related to photoresponsive poly(hexahydrotriazines) and related polymers. In an embodiment, a method of patterning a substrate includes forming a liquid poly(hemiaminal) material by a process that includes forming a reaction mixture comprising a polar solvent, paraformaldehyde, and an aminobenzene compound having photoreactive groups, and heating the reaction mixture at a temperature up to 50° C. The method further includes applying the liquid poly(hemiaminal) material to a substrate; patterning the liquid poly(hemiaminal) material with UV light; and curing the liquid poly(hemiaminal) material to form a cured poly(hexahydrotriazine) polymer.
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公开(公告)号：US10336914B2
公开(公告)日：2019-07-02
申请号：US14924174
申请日：2015-10-27
IPC分类号： C09D183/08 , C09D5/08 , C09D201/02 , C09D5/00
摘要： Methods and compositions related to chemically active hexahydrotriazine inorganic-organic hybrid coatings are described. The coatings have affinity for sulfur compounds, and thus may bind or capture sulfur containing contaminants and gases. The coatings have organosilicon containing functional groups and segments, and may also contain silica particles, which cumulatively enhances adhesion, abrasion resistance and further provides steric barriers to gaseous diffusion. The coatings have utility as protective barrier coatings in the field of electronics.
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公开(公告)号：US10246551B2
公开(公告)日：2019-04-02
申请号：US15449526
申请日：2017-03-03
IPC分类号： C08K5/49 , C08G63/12 , C08G63/78 , C08G63/692 , C09D5/18
摘要： A process for the production of a flame-retardant polymer is disclosed. The process includes reacting a polyol, for example glycerol, with an organophosphorus monochloride material to produce a phosphorus-functionalized polyol derivative. The process further includes reacting the phosphorus-functionalized polyol derivative with a polycarboxylic acid to form the flame-retardant polymer, wherein phosphorus is chemically bound to a polymer chain of the flame-retardant polymer.
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