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公开(公告)号：US10426807B2
公开(公告)日：2019-10-01
申请号：US15209724
申请日：2016-07-13
发明人： Bin Shi , Xiaolei Guo , Chung Wah Ma , Wei Zhang , Zhen Luo
IPC分类号： A61K36/48 , A61K36/00 , A61K36/481 , A61K38/39 , A61K31/7008 , A61K31/737 , A61K36/21 , A61K36/236 , A61K36/46 , A61K36/23
摘要： The invention relates to a bone and joint protection composition and use thereof. According to the composition, the four Chinese medicinal herbs Eucommiae Cortex, Achyranthis Bidentatae Radix, Astragali Radix and Chuanxiong Rhizoma are used, and the effects of enhancing the bone density, preventing and relieving osteoporosis, restraining the activity of osteoclast, promoting the function of bone cells, increasing the formation of calcified bone, promoting cartilage repair, delaying joint recession and repairing joint damage are achieved through multiple approaches and multiple levels. On the basis, by adding glucosamine hydrochloride, chondroitin sulfate and/or collagen, the bone density can be enhanced, the osteoporosis can be prevented and treated; the activity of the osteoclast can be restrained, the function of bone cells can be promoted, the formation of calcified bone can be increased, the cartilage repair can be promoted, joint recession can be delayed, and the joint damage can be repaired.
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公开(公告)号：US10821149B2
公开(公告)日：2020-11-03
申请号：US15175778
申请日：2016-06-07
发明人： Bin Shi , Xiaolei Guo , Chung Wah Ma , Chuixin Qin , Zhen Luo , Wei Zhang
IPC分类号： A61K36/8994 , A61K36/896 , A61K36/28 , A61K36/88 , A61K36/884 , A61K36/488 , A23L33/105 , A61K36/68 , A61K36/90
摘要： The present invention relates to the pharmaceutical field, particularly to a composition and the use thereof. The composition serves to lower uric acid through the combination of several traditional Chinese medicines of Smilacis glabra rhizoma, Cichorii herba, Plantaginis herba and Coicis semen. On the basis of the combination of the traditional Chinese medicines described above, the addition of Alismatis rhizoma is able to improve the effect of lowering uric acid more significantly. Further, on the basis of the combination of the traditional Chinese medicines described above, the addition of tuna was able to improve the effect of lowering uric acid more significantly. A comprehensive analysis of the experimental results described above indicates that the compositions provided in the present invention have a significant effect of lowering uric acid.
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公开(公告)号：US10278994B2
公开(公告)日：2019-05-07
申请号：US15141103
申请日：2016-04-28
发明人： Bin Shi , Xiaolei Guo , Chung Wah Ma , Ting Zhang , Wei Zhang
摘要： The present invention discloses a method for the preparation of skipjack tuna extract having hypouricemic effect and the use thereof, which is simple in processing operations, low in production cost, and is free from pollution. The prepared skipjack tuna extract has a potent hypouricemic effect, and has a significant therapeutic effect on hyperuricemia, with no toxic and side effects. The method in an example of the present invention comprises: pretreating skipjack tuna to obtain a skipjack tuna slurry; enzymolysing the skipjack tuna slurry to obtain a crude enzymolysis liquid; removing fishy smell and bitter taste, removing impurities by activated charcoal, and filtering to obtain a refinded enzymolysis liquid; concentrating under vacuum and spray-drying to obtain the skipjack tuna extract. The present invention further discloses use of the skipjack tuna extract in health care products or food products.
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