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公开(公告)号：US11981688B2
公开(公告)日：2024-05-14
申请号：US17841046
申请日：2022-06-15
Applicant: IMMUNOGEN, INC.
Inventor： Michael Reardon , Richard A. Silva
IPC: C07D487/04 , C07C231/12 , C07C233/07 , C07C319/20 , C07C321/20 , C07D519/00
CPC classification number: C07D519/00 , C07C231/12 , C07C233/07 , C07C319/20 , C07C321/20 , C07D487/04
Abstract: The invention provides novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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公开(公告)号：US11420982B2
公开(公告)日：2022-08-23
申请号：US16991700
申请日：2020-08-12
Applicant: IMMUNOGEN, INC.
Inventor： Baudouin Gérard , Manami Shizuka , Michael Louis Miller , Richard A. Silva
IPC: C07D487/04 , C07D519/00 , C07K5/083
Abstract: The invention relates to novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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公开(公告)号：US20210122768A1
公开(公告)日：2021-04-29
申请号：US17060611
申请日：2020-10-01
Applicant: IMMUNOGEN, INC.
Inventor： Michael Reardon , Richard A. Silva
IPC: C07D519/00 , C07C231/12 , C07C233/07 , C07C319/20 , C07C321/20 , C07D487/04
Abstract: The invention provides novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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公开(公告)号：US11981687B2
公开(公告)日：2024-05-14
申请号：US17841026
申请日：2022-06-15
Applicant: IMMUNOGEN, INC.
Inventor： Baudouin Gérard , Richard A. Silva , Michael Louis Miller , Manami Shizuka
IPC: C07D207/452 , C07C205/19 , C07D487/04 , C07D519/00 , C07D519/04
CPC classification number: C07D519/00 , C07C205/19 , C07D207/452 , C07D487/04 , C07D519/04
Abstract: The invention provides novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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公开(公告)号：US20210230114A1
公开(公告)日：2021-07-29
申请号：US17143723
申请日：2021-01-07
Applicant: IMMUNOGEN, INC.
Inventor： Michael Reardon , Richard A. Silva
IPC: C07D207/448 , C07D519/00
Abstract: The invention provides novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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Patent Agency Ranking
公开(公告)号：US20210171546A1
公开(公告)日：2021-06-10
申请号：US16991700
申请日：2020-08-12
Applicant: IMMUNOGEN, INC.
Inventor： Baudouin Gérard , Manami Shizuka , Michael Louis Miller , Richard A. Silva
IPC: C07D519/00 , C07K5/083 , C07D487/04
Abstract: The invention relates to novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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![Methods of preparing substituted 12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indoles](/abs-image/US/2021/04/06/US10968228B2/abs.jpg.150x150.jpg)
7.发明授权公开(公告)号：US10968228B2
公开(公告)日：2021-04-06
申请号：US16560379
申请日：2019-09-04
Applicant: IMMUNOGEN, INC.
Inventor： Baudouin Gérard , Richard A. Silva , Michael Louis Miller , Manami Shizuka
IPC: C07D487/22 , C07D487/04 , C07D209/12
Abstract: The invention provides novel methods for preparing indolinobenzodiazepine monomer compounds of formula (I) below and their synthetic precursors:
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公开(公告)号：US10913713B2
公开(公告)日：2021-02-09
申请号：US16679593
申请日：2019-11-11
Applicant: IMMUNOGEN, INC.
Inventor： Michael Reardon , Richard A. Silva
IPC: C07D207/452 , C07D487/04 , C07D207/448 , C07D519/00
Abstract: The invention provides novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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公开(公告)号：US20200017526A1
公开(公告)日：2020-01-16
申请号：US16448261
申请日：2019-06-21
Applicant: IMMUNOGEN, INC.
Inventor： Baudouin Gérard , Manami Shizuka , Michael Louis Miller , Richard A. Silva
IPC: C07D519/00 , C07D487/04 , C07K5/083
Abstract: The invention relates to novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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公开(公告)号：US10370389B2
公开(公告)日：2019-08-06
申请号：US15837832
申请日：2017-12-11
Applicant: IMMUNOGEN, INC.
Inventor： Baudouin Gérard , Manami Shizuka , Michael Louis Miller , Richard A. Silva
IPC: C07D519/00 , C07D487/04 , C07K5/083
Abstract: The invention relates to novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
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