公开(公告)号：US20240002436A1

公开(公告)日：2024-01-04

申请号：US18036382

申请日：2021-11-15

申请人： Hofseth Biocare ASA

发明人： Bomi FRAMROZE ,  Crawford Linden Alexander CURRIE

IPC分类号： C07K5/103 ,  C07K5/107 ,  C07K5/062 ,  C07K5/065

CPC分类号： C07K5/101 ,  C07K5/1016 ,  C07K5/1008 ,  C07K5/06026 ,  C07K5/06034 ,  C07K5/06078 ,  A61K38/00

摘要： Provided herein are methods for treating certain inflammatory and/or respiratory conditions, disorders and diseases in humans using compositions comprising lipopeptides, including microcolins. The compositions are orally administered. The humans suitable for such treatments include those largely resistant to medical and surgical interventions, such as steroid treatments. The compositions described herein have also been found to reduce cosinophil effector function.