公开(公告)号：US20240344973A1

公开(公告)日：2024-10-17

申请号：US18293669

申请日：2022-07-05

Applicant: Hitachi High-Tech Corporation

Inventor： Yuusuke KOURAI ,  Mutsumi SUZUKI ,  Kota SASAKI ,  Gorou YOSHIDA ,  Yuto TANAKA ,  Kenta TSUNASHIMA

IPC: G01N21/27 ,  G01N21/25

CPC classification number: G01N21/272 ,  G01N21/253

Abstract: Provided is a chemical analysis device that facilitates the estimation of a failure position in failure diagnosis. This chemical analysis device comprises a plurality of reaction cells into which specimens and reagents are dispensed and measures the absorbances of mixed liquids of the specimens and reagents accommodated in the reaction cells using a light measurement system for emitting light onto the mixed liquids and measuring the light that has passed through the mixed liquids. The chemical analysis device comprises a diagnosis unit for failure diagnosis. The diagnosis unit accumulates time-series light-measurement-system data measured using a sample specimen for failure diagnosis and a reagent for failure diagnosis, creates a light measurement data population for failure diagnosis for each prescribed reaction cell, and carries out failure diagnosis by comparing the light measurement data of the light measurement data populations created for each prescribed reaction cell with a preset threshold.

公开(公告)号：US20210270707A1

公开(公告)日：2021-09-02

申请号：US17255714

申请日：2019-05-13

Applicant: Hitachi High-Tech Corporation

Inventor： Yuusuke KOURAI ,  Kota SASAKI ,  Jun MAEDA ,  Azusa YAMADA ,  Tetsuyoshi ONO

IPC: G01N1/38 ,  B01F11/02

Abstract: This chemical analysis device is provided with: a plurality of ultrasonic elements; a waveform generator which generates an ultrasonic waveform; a determiner which determines the positions and the number of ultrasonic elements to be driven from among the plurality of ultrasonic elements; a variable matching circuit which, on the basis of the determination result, matches impedance between the waveform generator and each of the ultrasonic elements to be driven; and a switch which selects the ultrasonic elements to be driven from among the plurality of the ultrasonic elements.

公开(公告)号：US20250067588A1

公开(公告)日：2025-02-27

申请号：US18723771

申请日：2022-11-22

Applicant: Hitachi High-Tech Corporation

Inventor： Yuusuke KOURAI ,  Masaru TATEMI ,  Mutsumi SUZUKI ,  Kota SASAKI ,  Gorou YOSHIDA ,  Yuto TANAKA ,  Kenta TSUNASHIMA

IPC: G01F23/26

Abstract: Provided is a chemical analysis apparatus which has a stirring function for stirring, by using an ultrasonic element, a reagent or the like and a sample to be measured, and with which it is possible to infer the presence or absence of a reaction liquid and estimate the liquid amount of the reaction liquid without using a means such as a sensor and a visual inspection. This chemical analysis apparatus has an ultrasonic stirring mechanism and is characterized in that the ultrasonic stirring mechanism comprises: a piezoelectric element; a plurality of electrodes provided to the piezoelectric element; a power source unit for applying voltage to the electrodes; a detection unit for measuring electric impedance for each of the plurality of electrodes or for any combination of the electrodes; and an analysis unit for determining the liquid amount in a reaction vessel from the electric impedance detected by the detection unit. The chemical analysis apparatus is characterized in that the detection unit measures the electric impedance in a state where a reaction vessel having two or more different amounts of liquid dispensed therein faces the piezoelectric element, and the analysis unit estimates the liquid amount in the reaction vessel on the basis of the change amount in the electric impedance measured by the detection unit.

公开(公告)号：US20220410152A1

公开(公告)日：2022-12-29

申请号：US17778326

申请日：2020-11-05

Applicant: Hitachi High-Tech Corporation

Inventor： Yuusuke KOURAI ,  Toshiyuki INABE ,  Shunsuke MIYAMOTO

IPC: B01L3/00 ,  G01N1/38

Abstract: The present invention provides a chemical analyzer with highly reliable agitation performance, said chemical analyzer not only diagnosing the deterioration of a piezoelectric element, but also diagnosing the deformation and displacement of a reaction container and diagnosing the normality of the liquid quantity of a substance to be agitated in the reaction container. This chemical analyzer is characterized by comprising: an agitating mechanism that uses acoustic waves to agitate a sample and a reagent within a reaction container, generates acoustic waves using a piezoelectric element, and has an acoustic wave sensor for detecting the acoustic waves; and a controller that controls the agitating mechanism. Said chemical analyzer is further characterized in that the controller has: an acoustic wave detection unit that processes a detection signal detected by the acoustic wave sensor; a normality information memory in which normal-time information is stored; a signal intensity determination unit that compares the acoustic wave amplitude and acoustic wave frequency transmitted from the acoustic wave detection unit with the acoustic wave amplitude and acoustic wave frequency stored in the normality information memory; and a repeat period determination unit that compares the acoustic wave period characteristic transmitted from the acoustic wave detection unit with the acoustic wave period characteristic stored in the normality information memory.