公开(公告)号：US20170258784A1

公开(公告)日：2017-09-14

申请号：US15608032

申请日：2017-05-30

Applicant: HELPERBY THERAPEUTICS LIMITED

Inventor： Petra Helga BECK ,  Marc Barry BROWN ,  David Edward CLARK ,  Anthony COATES ,  Hazel Joan DYKE ,  Yanmin HU ,  Derek John LONDESBROUGH ,  Keith MILLS ,  Thomas David PALLIN ,  Gary Patrick REID ,  Gerlinda STODDART

IPC: A61K31/4709 ,  A61L2/00 ,  A61K31/4439

CPC classification number: A61K31/4745 ,  A01N43/90 ,  A61K31/43 ,  A61K31/4439 ,  A61K31/4706 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/497 ,  A61K31/546 ,  A61K31/7052 ,  A61L2/0088 ,  C07D471/04 ,  Y02A50/401 ,  Y02A50/404 ,  Y02A50/406 ,  Y02A50/411 ,  Y02A50/469 ,  Y02A50/473 ,  Y02A50/475 ,  Y02A50/478 ,  Y02A50/479 ,  Y02A50/481 ,  Y02A50/483

Abstract: There is provided the use of compounds of formula I wherein R1, R2, R3 and X have meanings given in the description, for the preparation of a medicament for killing clinically latent microorganisms. There is also provided the use of compounds of formula I for treating microbial infections, as well as certain compounds of formula I per se.