公开(公告)号：US20210309725A1

公开(公告)日：2021-10-07

申请号：US16860239

申请日：2020-04-28

Applicant: H. Lundbeck A/S

Inventor： Roger K. Cady ,  Jeffrey T.L. Smith ,  Joseph Hirman

IPC: C07K16/18 ,  A61K9/00 ,  A61P25/06

Abstract: Methods for treatment of most bothersome symptom (MBS) associated with migraine are provided. Exemplary methods provide improvement in MBS associated with migraine within 1 month of administration og anti-CGRP antibodies of the invention. Also provided are methods for improvement of patient impression of change (PGIC) associated with migraine. Exemplary methods comprise administration of an anti-CGRP antagonistic antibody to a patient in need thereof.

公开(公告)号：US12215144B2

公开(公告)日：2025-02-04

申请号：US18609223

申请日：2024-03-19

Applicant: H. LUNDBECK A/S

Inventor： Roger K. Cady ,  Jeffrey T.L. Smith ,  Joseph Hirman ,  Barbara Schaeffler ,  Lahar Mehta

IPC: C07K16/18 ,  A61K9/00 ,  A61K31/4172 ,  A61K38/00 ,  A61K39/00 ,  A61K39/395 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06

Abstract: Methods for rapid treatment of chronic migraine are provided. Exemplary methods provide relief from migraine within 24 hours of administration. Also provided are methods for acute treatment of migraine. Exemplary methods comprise administration of an anti-CGRP antagonist antibody to a patient in need thereof.

公开(公告)号：US20240270832A1

公开(公告)日：2024-08-15

申请号：US18609223

申请日：2024-03-19

Applicant: H. LUNDBECK A/S

Inventor： Roger K. Cady ,  Jeffrey T.L. Smith ,  Joseph Hirman ,  Barbara Schaeffler ,  Lahar Mehta

IPC: C07K16/18 ,  A61K9/00 ,  A61K31/4172 ,  A61K38/00 ,  A61K39/00 ,  A61K39/395 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06

CPC classification number: C07K16/18 ,  A61K9/0019 ,  A61K31/4172 ,  A61K39/3955 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06 ,  A61K38/00 ,  A61K2039/505 ,  A61K2039/545 ,  C07K2317/24

Abstract: Methods for rapid treatment of chronic migraine are provided. Exemplary methods provide relief from migraine within 24 hours of administration. Also provided are methods for acute treatment of migraine. Exemplary methods comprise administration of an anti-CGRP antagonist antibody to a patient in need thereof.

公开(公告)号：US20240239880A1

公开(公告)日：2024-07-18

申请号：US18609247

申请日：2024-03-19

Applicant: H. LUNDBECK A/S

Inventor： Roger K. Cady ,  Jeffrey T.L. Smith ,  Joseph Hirman ,  Barbara Schaeffler ,  Lahar Mehta

IPC: C07K16/18 ,  A61K9/00 ,  A61K31/4172 ,  A61K39/395 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06 ,  A61K38/00 ,  A61K39/00

CPC classification number: C07K16/18 ,  A61K9/0019 ,  A61K31/4172 ,  A61K39/3955 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06 ,  A61K38/00 ,  A61K2039/505 ,  A61K2039/545 ,  C07K2317/24

Abstract: Methods for immediate relief of migraine or headache are provided comprising the administration of an anti-CGRP antagonist antibody to a patient in need thereof.

公开(公告)号：US20240067708A1

公开(公告)日：2024-02-29

申请号：US18173124

申请日：2023-02-23

Applicant: H. Lundbeck A/S

Inventor： Roger K. Cady ,  Jeffrey T.L. Smith ,  Joseph Hirman ,  Barbara Schaeffler ,  Lahar Mehta

IPC: C07K16/18 ,  A61K9/00 ,  A61K31/4172 ,  A61K39/395 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06

CPC classification number: C07K16/18 ,  A61K9/0019 ,  A61K31/4172 ,  A61K39/3955 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06 ,  A61K2039/505

Abstract: Methods for immediate relief of migraine or headache are provided comprising the administration of an anti-CGRP antagonist antibody to a patient in need thereof.

公开(公告)号：US11639380B2

公开(公告)日：2023-05-02

申请号：US16736925

申请日：2020-01-08

Applicant: H. LUNDBECK A/S

Inventor： Roger K. Cady ,  Jeffrey T. L. Smith ,  Joseph Hirman ,  Barbara Schaeffler ,  Lahar Mehta

IPC: C07K16/18 ,  A61K9/00 ,  A61K39/395 ,  A61K31/4172 ,  A61K47/26 ,  A61K38/00 ,  A61P25/06 ,  A61K45/06 ,  A61K39/00

Abstract: Methods for rapid treatment of chronic migraine are provided. Exemplary methods provide relief from migraine within 24 hours of administration. Also provided are methods for acute treatment of migraine. Exemplary methods comprise administration of an anti-CGRP antagonist antibody to a patient in need thereof.

公开(公告)号：US12215145B2

公开(公告)日：2025-02-04

申请号：US18609247

申请日：2024-03-19

Applicant: H. LUNDBECK A/S

Inventor： Roger K. Cady ,  Jeffrey T. L. Smith ,  Joseph Hirman ,  Barbara Schaeffler ,  Lahar Mehta

IPC: C07K16/18 ,  A61K9/00 ,  A61K31/4172 ,  A61K38/00 ,  A61K39/00 ,  A61K39/395 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06

Abstract: Methods for immediate relief of migraine or headache are provided comprising the administration of an anti-CGRP antagonist antibody to a patient in need thereof.

公开(公告)号：US20240343784A1

公开(公告)日：2024-10-17

申请号：US18511241

申请日：2023-11-16

Applicant: H. Lundbeck A/S

Inventor： Roger K. Cady ,  Jeffrey T.L. Smith ,  Joseph Hirman ,  Barbara Schaeffler ,  Lahar Mehta

IPC: C07K16/18 ,  A61K39/00 ,  A61K47/10 ,  A61K47/18 ,  A61K47/34 ,  A61P25/06

CPC classification number: C07K16/18 ,  A61K47/10 ,  A61K47/183 ,  A61K47/34 ,  A61P25/06 ,  A61K2039/505 ,  A61K2039/545 ,  C07K2317/20 ,  C07K2317/41 ,  C07K2317/565

Abstract: Methods for treatment or prevention of medication overuse headache are provided. Exemplary methods comprise administration of an anti-CGRP antagonist antibody to a patient in need thereof.

公开(公告)号：US20240101653A1

公开(公告)日：2024-03-28

申请号：US18182822

申请日：2023-03-13

Applicant: H. Lundbeck A/S

Inventor： Roger K. Cady ,  Jeffrey T.L. Smith ,  Joseph Hirman

IPC: C07K16/18 ,  A61K9/00 ,  A61P25/06

CPC classification number: C07K16/18 ,  A61K9/0019 ,  A61P25/06 ,  A61K2039/545

Abstract: Methods for treatment of most bothersome symptom (MBS) associated with migraine are provided. Exemplary methods provide improvement in MBS associated with migraine within 1 month of administration og anti-CGRP antibodies of the invention. Also provided are methods for improvement of patient impression of change (PGIC) associated with migraine. Exemplary methods comprise administration of an anti-CGRP antagonistic antibody to a patient in need thereof.

公开(公告)号：US20240076359A1

公开(公告)日：2024-03-07

申请号：US18173116

申请日：2023-02-23

Applicant: H. Lundbeck A/S

Inventor： Roger K. Cady ,  Jeffrey T.L. Smith ,  Joseph Hirman ,  Barbara Schaeffler ,  Lahar Mehta

IPC: C07K16/18 ,  A61K9/00 ,  A61K31/4172 ,  A61K39/395 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06

CPC classification number: C07K16/18 ,  A61K9/0019 ,  A61K31/4172 ,  A61K39/3955 ,  A61K45/06 ,  A61K47/26 ,  A61P25/06 ,  A61K2039/505

Abstract: Methods for rapid treatment of chronic migraine are provided. Exemplary methods provide relief from migraine within 24 hours of administration. Also provided are methods for acute treatment of migraine. Exemplary methods comprise administration of an anti-CGRP antagonist antibody to a patient in need thereof.