Creatinol o-phosphate and synthesis method thereof
    1.
    发明申请
    Creatinol o-phosphate and synthesis method thereof 审中-公开
    磷酸肌醇及其合成方法

    公开(公告)号:US20110105786A1

    公开(公告)日:2011-05-05

    申请号:US12590140

    申请日:2009-11-02

    CPC classification number: C07C279/08 C07F9/091

    Abstract: A creatinol O-phosphate is formed by chemically reacting a creatinol sulfate of creatinol compound with sulfuric acid to form a protected creatinol sulfate as a transition state of the synthesis process of the creatinol O-phosphate, wherein the protected creatinol is further reacted with one of P2O5, CIPO3H2, and POCl3 to form the creatinol O-phosphate. The method of producing the protected creatinol sulfate includes a step of adding sulfuric acid into a creatinol sulfate to form a protected creatinol sulfate as the protected functional group. Therefore, the creatinol O-phosphate is formed by the process including the steps of chemically reacting the protected creatinol sulfate with one of POCl3, CIPO3OH2, and P2O5 to form a creatinol O-phosphate solution; and crystallizing the creatinol O-phosphate solution to obtain crystallized creatinol O-phosphate.

    Abstract translation: 通过使肌酸酐化合物的硫酸肌酸酐与硫酸化学反应形成硫酸肌酸酐作为肌醇酐磷酸酯的合成过程的过渡态,形成肌酸酐O-磷酸酯,其中保护的肌醇酐进一步与 P2O5,CIPO3H2和POCl3,以形成磷酸肌醇酐。 生产受保护的硫酸肌酸酐的方法包括将硫酸加入到硫酸肌酐中以形成受保护的硫酸肌酸酐作为受保护的官能团的步骤。 因此,通过使保护的硫酸肌酸酐与POCl 3,CIPO 3 OH 2和P 2 O 5中的一种化学反应的方法形成磷酸肌酸酐溶液,从而形成磷酸肌酸酐。 并使肌酸酐O-磷酸盐溶液结晶,得到结晶的磷酸肌酐。

    Production process of dicreatine malate
    2.
    发明授权
    Production process of dicreatine malate 失效
    苹果酸肌酸的生产过程

    公开(公告)号:US07339077B2

    公开(公告)日:2008-03-04

    申请号:US10842800

    申请日:2004-05-10

    Applicant: Guoji Zhang

    Inventor: Guoji Zhang

    CPC classification number: C07C277/08 C07C279/14

    Abstract: A process of producing dicreatine malate with high purity, includes the steps of providing a predetermined amount of malic acid, agitating a predetermined amount of anhydrous alcohol to the malic acid to obtain a first solution, filtering the first solution to form a clear solution, agitating a predetermined amount of creatine to the clear solution to obtain a second solution, centrifuging the second solution to obtain a wet dicreatine malate and a separated alcohol, and drying the wet dicreatine malate to produce a dicreatine. Because of its low energy consumption, this process produces dicreatine malate effectively.

    Abstract translation: 制备高纯度苹果酸肌酐的方法包括以下步骤:提供预定量的苹果酸,向苹果酸中搅拌预定量的无水醇以获得第一溶液,过滤第一溶液以形成澄清溶液,搅拌 将预定量的肌酸提供到透明溶液中以获得第二溶液,离心第二溶液以获得湿的苹果酸湿的苹果酸和分离的醇,并干燥湿的肌酸二苹果酸酯以产生肌酸。 由于其能量消耗低,该方法有效地产生苹果酸肌酸酐。

    Process for preparation of L-Arginine α-ketoglutarate 1:1 and 2:1
    3.
    发明授权
    Process for preparation of L-Arginine α-ketoglutarate 1:1 and 2:1 失效
    L-精氨酸α-酮戊二酸1:1和2:1的制备方法

    公开(公告)号:US08754256B2

    公开(公告)日:2014-06-17

    申请号:US12925125

    申请日:2010-10-13

    Applicant: Guoji Zhang

    Inventor: Guoji Zhang

    Abstract: A process for preparation of α-ketoglutaric acid, L-arginine α-ketoglutarate 1:1 and 2:1 includes the following steps. Provide a α-ketoglutaratic acid aqueous solution at an adjusted concentration. Add one equivalent mole of solid L-arginine to the α-ketoglutaratic acid aqueous solution. Stir and allow reaction under a controlled temperature. Obtain a resulting L-arginine α-ketoglutarate 1:1 solution with a pH of approximately 3˜4 or L-arginine α-ketoglutarate 2:1 solution with a pH of approximately 6.5˜7. Obtain a final product of L-arginine α-ketoglutarate 1:1 or 2:1 through spay drying. The yield of the final product is approximately 94% for L-arginine α-ketoglutarate 1:1 and 97% for L-arginine α-ketoglutarate 2:1 through the process. Large amount of solvents is eliminated and reaction time is shortened but the yield is increased, hence realizing mass production through reactor in a cost and time effective manner.

    Abstract translation: 制备α-酮戊二酸,α-酮戊二酸L-精氨酸1:1和2:1的方法包括以下步骤。 提供调节浓度的α-酮戊二酸水溶液。 向α-酮戊二酸水溶液中加入1当量的固体L-精氨酸。 搅拌并允许在受控温度下进行反应。 得到pH约为3〜4的所得L-精氨酸α-酮戊二酸1:1溶液或pH约为6.5〜7的L-精氨酸α-酮戊二酸2:1溶液。 通过干燥干燥获得1 - 1或2:1 L-精氨酸α-酮戊二酸的最终产物。 通过该过程,最终产物的L-精氨酸α-酮戊二酸酯的产率为约94%,α-酮戊二酸L-精氨酸为1:1。 消除大量的溶剂,缩短反应时间,提高产率,从而以成本和时间有效的方式实现反应堆的批量生产。

    Production process of dicreatine malate
    4.
    发明申请
    Production process of dicreatine malate 失效
    苹果酸肌酸的生产过程

    公开(公告)号:US20050250962A1

    公开(公告)日:2005-11-10

    申请号:US10842800

    申请日:2004-05-10

    Applicant: Guoji Zhang

    Inventor: Guoji Zhang

    CPC classification number: C07C277/08 C07C279/14

    Abstract: A process of producing dicreatine malate with high purity, includes the steps of providing a predetermined amount of malic acid, agitating a predetermined amount of anhydrous alcohol to the malic acid to obtain a first solution, filtering the first solution to form a clear solution, agitating a predetermined amount of creatine to the clear solution to obtain a second solution, centrifuging the second solution to obtain a wet dicreatine malate and a separated alcohol, and drying the wet dicreatine malate to produce a dicreatine. Because of its low energy consumption, this process produces dicreatine malate effectively.

    Abstract translation: 制备高纯度苹果酸肌酐的方法包括以下步骤:提供预定量的苹果酸,向苹果酸中搅拌预定量的无水醇以获得第一溶液,过滤第一溶液以形成澄清溶液,搅拌 将预定量的肌酸提供到透明溶液中以获得第二溶液,离心第二溶液以获得湿的苹果酸湿的苹果酸和分离的醇,并干燥湿的肌酸二苹果酸酯以产生肌酸。 由于其能量消耗低,该方法有效地产生苹果酸肌酸酐。

    Solar thermal energy - field electron emission power generation device

    公开(公告)号:US20180048258A1

    公开(公告)日:2018-02-15

    申请号:US15121031

    申请日:2016-03-07

    Abstract: The present invention relates to a solar thermal energy-field electron emission power generation device, which is formed by a solar cooker and a heat-field electron emission power generation body. Based on the metal heat-field electron emission experiment, magnetic focusing and magnetic insulation are adopted to form the power generation device, which has characteristics of environmental protection, low cost and high efficiency. Therefore, the power generation device of the present invention can be widely applied to companies and individuals without common electric circuits, such as graze, sentry post, forest protection, cultivation of high seas, and marine power.

    Coreless permanent magnet motor with surface charged magnet
    6.
    发明授权
    Coreless permanent magnet motor with surface charged magnet 有权
    无磁永磁电动机带表面带电磁铁

    公开(公告)号:US09112401B2

    公开(公告)日:2015-08-18

    申请号:US13179847

    申请日:2011-07-11

    CPC classification number: H02K21/24

    Abstract: A coreless permanent motor has a stator and a rotor rotatably mounted to the stator. One of the stator or the rotor has at least one winding disc (28). The other one of the stator or the rotor has at least one surface charged magnet disc (33). The winding disc (28) or the magnet disc (33) is formed by two or more sector shaped units that are mounted to two or more support members (27) respectively. The winding disc (28) or the magnet disc (33) is formed by closing the support member (27) and the closed support members (27) form a cylindrical housing. Thus, the structure of the coreless motor is simplified.

    Abstract translation: 无芯永磁马达具有可转动地安装在定子上的定子和转子。 定子或转子中的一个具有至少一个卷绕盘(28)。 定子或转子中的另一个具有至少一个表面带电磁盘(33)。 卷绕盘(28)或磁盘(33)由分别安装到两个或更多个支撑构件(27)的两个或更多个扇形单元形成。 卷绕盘(28)或磁盘(33)通过关闭支撑构件(27)和闭合的支撑构件(27)形成圆柱形壳体而形成。 因此,无芯电动机的结构简化。

    Process for preparation of L-Arginine alpha-ketoglutarate 1:1 and 2:1
    7.
    发明申请
    Process for preparation of L-Arginine alpha-ketoglutarate 1:1 and 2:1 失效
    L-精氨酸α-酮戊二酸1:1和2:1的制备方法

    公开(公告)号:US20120095260A1

    公开(公告)日:2012-04-19

    申请号:US12925125

    申请日:2010-10-13

    Applicant: Guoji Zhang

    Inventor: Guoji Zhang

    Abstract: A process for preparation of α-ketoglutaric acid, L-arginine α-ketoglutarate 1:1 and 2:1, comprising the steps of: providing a α-ketoglutaratic acid aqueous solution at an adjusted concentration; adding one equivalent mole of solid L-arginine to the α-ketoglutaratic acid aqueous solution; stirring and allowing reaction under a controlled temperature; (e) obtaining a resulting L-arginine α-ketoglutarate 1:1 solution with a pH of approximately 3˜4 or L-arginine α-ketoglutarate 2:1 solution with a pH of approximately 6.5˜7; and obtaining a final product of L-arginine α-ketoglutarate 1:1 or 2:1 through spay drying. The yield of the final product is approximately 94% for L-arginine α-ketoglutarate 1:1 and 97% for L-arginine α-ketoglutarate 2:1 through the process. Large amount of solvents is eliminated and reaction time is shortened but the yield is increased, hence realizing mass production through reactor in a cost and time effective manner.

    Abstract translation: 一种制备α-酮戊二酸,α-酮戊二酸L-精氨酸1:1和2:1的方法,包括以下步骤:提供调节浓度的α-酮戊二酸水溶液; 向α-酮戊二酸水溶液中加入1当量的固体L-精氨酸; 搅拌并允许在受控温度下反应; (e)获得pH约为3〜4的所得L-精氨酸α-酮戊二酸1:1溶液或pH约6.5〜7的L-精氨酸α-酮戊二酸2:1溶液; 并通过干燥干燥获得α-酮戊二酸L-精氨酸1:1或2:1的最终产物。 通过该过程,最终产物的L-精氨酸α-酮戊二酸酯的产率为约94%,α-酮戊二酸L-精氨酸为1:1。 消除大量的溶剂,缩短反应时间,提高产率,从而以成本和时间有效的方式实现反应堆的批量生产。

    Solar thermal energy—field electron emission power generation device

    公开(公告)号:US10153723B2

    公开(公告)日:2018-12-11

    申请号:US15121031

    申请日:2016-03-07

    Abstract: The present invention relates to a solar thermal energy-field electron emission power generation device, which is formed by a solar cooker and a heat-field electron emission power generation body. Based on the metal heat-field electron emission experiment, magnetic focusing and magnetic insulation are adopted to form the power generation device, which has characteristics of environmental protection, low cost and high efficiency. Therefore, the power generation device of the present invention can be widely applied to companies and individuals without common electric circuits, such as graze, sentry post, forest protection, cultivation of high seas, and marine power.

    Process for preparation of l-arginine alpha-ketoglutarate 1:1 and 2:1
    9.
    发明申请
    Process for preparation of l-arginine alpha-ketoglutarate 1:1 and 2:1 审中-公开
    制备α-精氨酸α-酮戊二酸1:1和2:1的方法

    公开(公告)号:US20140187815A1

    公开(公告)日:2014-07-03

    申请号:US13694727

    申请日:2012-12-28

    Applicant: Guoji Zhang

    Inventor: Guoji Zhang

    Abstract: A process for preparation of α-ketoglutaric acid, L-arginine α-ketoglutarate 1:1 and 2:1, comprising the steps of: providing a α-ketoglutaratic acid aqueous solution at an adjusted concentration; adding one equivalent mole of solid L-arginine to the α-ketoglutaratic acid aqueous solution; stirring and allowing reaction under a controlled temperature; (e) obtaining a resulting L-arginine α-ketoglutarate 1:1 solution with a pH of approximately 3˜4 or L-arginine α-ketoglutarate 2:1 solution with a pH of approximately 6.5˜7; and obtaining a final product of L-arginine α-ketoglutarate 1:1 or 2:1 through spay drying. The yield of the final product is approximately 94% for L-arginine α-ketoglutarate 1:1 and 97% for L-arginine α-ketoglutarate 2:1 through the process. Large amount of solvents is eliminated and reaction time is shortened but the yield is increased, hence realizing mass production through reactor in a cost and time effective manner.

    Abstract translation: 一种制备α-酮戊二酸,α-酮戊二酸L-精氨酸1:1和2:1的方法,包括以下步骤:提供调节浓度的α-酮戊二酸水溶液; 向α-酮戊二酸水溶液中加入1当量的固体L-精氨酸; 搅拌并允许在受控温度下反应; (e)获得pH约为3〜4的所得L-精氨酸α-酮戊二酸1:1溶液或pH约6.5〜7的L-精氨酸α-酮戊二酸2:1溶液; 并通过干燥干燥获得α-酮戊二酸L-精氨酸1:1或2:1的最终产物。 通过该过程,最终产物的L-精氨酸α-酮戊二酸酯的产率为约94%,α-酮戊二酸L-精氨酸为1:1。 消除大量的溶剂,缩短反应时间,提高产率,从而以成本和时间有效的方式实现反应堆的批量生产。

    Creatine hydrochloride and manufacturing method thereof
    10.
    发明申请
    Creatine hydrochloride and manufacturing method thereof 审中-公开
    肌酸盐酸盐及其制造方法

    公开(公告)号:US20140171682A1

    公开(公告)日:2014-06-19

    申请号:US13694590

    申请日:2012-12-14

    Applicant: Guoji Zhang

    Inventor: Guoji Zhang

    CPC classification number: C07C277/08 C07C279/14

    Abstract: A manufacturing method for preparing creatine hydrochlorides includes the steps of using absolute ethyl alcohol as the cleaning agent to reduce production costs and to avoid harm to the human body resulting in the production process.

    Abstract translation: 用于制备盐酸肌酸的制备方法包括以下步骤:使用无水乙醇作为清洁剂,以降低生产成本并避免对人体造成损害,从而导致生产过程。

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