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公开(公告)号:US10696738B2
公开(公告)日:2020-06-30
申请号:US15363223
申请日:2017-02-02
申请人: Glaxo Group Limited
发明人: Elena De Angelis , Carolyn Enever , Haiqun Liu , Oliver Schon
IPC分类号: A61K39/00 , C07K16/18 , C07K14/56 , C07K14/575 , C07K16/28
摘要: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
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公开(公告)号:US09751935B2
公开(公告)日:2017-09-05
申请号:US14862818
申请日:2015-09-23
申请人: GLAXO GROUP LIMITED
发明人: Elena De Angelis , Carolyn Enever , Haiqun Liu , Oliver Schon
IPC分类号: C07K16/18 , C07K14/56 , C07K14/575 , C07K16/28
CPC分类号: C07K16/18 , C07K14/56 , C07K14/57563 , C07K16/2878 , C07K2317/14 , C07K2317/31 , C07K2317/34 , C07K2317/565 , C07K2317/569 , C07K2317/92 , C07K2319/00 , C07K2319/31
摘要: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
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公开(公告)号:US20160075774A1
公开(公告)日:2016-03-17
申请号:US14862818
申请日:2015-09-23
申请人: Glaxo Group Limited
发明人: Elena DE ANGELIS , Carolyn Enever , Haiqun Liu , Oliver Schon
IPC分类号: C07K16/18
CPC分类号: C07K16/18 , C07K14/56 , C07K14/57563 , C07K16/2878 , C07K2317/14 , C07K2317/31 , C07K2317/34 , C07K2317/565 , C07K2317/569 , C07K2317/92 , C07K2319/00 , C07K2319/31
摘要: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
摘要翻译: 本发明涉及抗血清白蛋白免疫球蛋白单可变结构域DOM7h-14的改进变体,以及包含这些变体,组合物,核酸,载体和宿主的配体和药物偶联物。
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公开(公告)号:US20140140996A1
公开(公告)日:2014-05-22
申请号:US14168168
申请日:2014-01-30
申请人: Glaxo Group Limited
发明人: Edward COULSTOCK , Elena De Angelis , Haiqun Liu , Oliver Schon
IPC分类号: C07K16/18
CPC分类号: C07K16/18 , A61K2039/505 , C07K2317/55 , C07K2317/56 , C07K2317/569 , C07K2317/92 , C07K2319/31
摘要: The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts.
摘要翻译: 本发明涉及改进的抗血清白蛋白免疫球蛋白单可变结构域,以及包含这种可变结构域,组合物,核酸,载体和宿主的配体和药物偶联物。
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