公开(公告)号：US20100168780A1

公开(公告)日：2010-07-01

申请号：US12714362

申请日：2010-02-26

Applicant: Gino Rigotti ,  Guido Baroni

Inventor： Gino Rigotti ,  Guido Baroni

IPC: A61M29/00

CPC classification number: A61F2/12 ,  A61B90/02 ,  A61F2250/0003 ,  A61H9/005

Abstract: A tissue expansion device implanted in a non-activated state over a region of desired tissue growth. Once implanted and positioned the device is activated creating a supporting structure that creates a convex shaped dome over the underlying tissue. The convex shaped dome formed by the tissue expansion device places a tensile stress against the underlying tissue that promotes tissue growth. Alone or with the introduction of tissue enhancing agents and/or adipose tissue, new tissue within the convex shaped void grows until a balance is achieved eliminating the induced stress. Periodically the tissue expansion devices is again activated and enlarged creating an even larger void. Again, the newly enlarged void places additional tensile stress on the underlying tissue thus repeating the cycle of new tissue growth. Once the desired amount of tissue growth has been achieved the device is deactivated and removed.

公开(公告)号：US20100161052A1

公开(公告)日：2010-06-24

申请号：US12714293

申请日：2010-02-26

Applicant: Gino Rigotti ,  Guido Baroni

Inventor： Gino Rigotti ,  Guido Baroni

IPC: A61F2/12

CPC classification number: A61F2/12 ,  A61B90/02 ,  A61F2250/0003 ,  A61H9/005

Abstract: A tissue expansion device implanted in a non-activated state over a region of desired tissue growth. Once implanted and positioned the device is activated creating a supporting structure that creates a convex shaped dome over the underlying tissue. The convex shaped dome formed by the tissue expansion device places a tensile stress against the underlying tissue that promotes tissue growth. Alone or with the introduction of tissue enhancing agents and/or adipose tissue, new tissue within the convex shaped void grows until a balance is achieved eliminating the induced stress. Periodically the tissue expansion devices is again activated and enlarged creating an even larger void. Again, the newly enlarged void places additional tensile stress on the underlying tissue thus repeating the cycle of new tissue growth. Once the desired amount of tissue growth has been achieved the device is deactivated and removed.

公开(公告)号：US20100160948A1

公开(公告)日：2010-06-24

申请号：US12714349

申请日：2010-02-26

Applicant: Gino Rigotti ,  Guido Baroni

Inventor： Gino Rigotti ,  Guido Baroni

IPC: A61M29/00

CPC classification number: A61F2/12 ,  A61B90/02 ,  A61F2250/0003 ,  A61H9/005

Abstract: A tissue expansion device implanted in a non-activated state over a region of desired tissue growth. Once implanted and positioned the device is activated creating a supporting structure that creates a convex shaped dome over the underlying tissue. The convex shaped dome formed by the tissue expansion device places a tensile stress against the underlying tissue that promotes tissue growth. Alone or with the introduction of tissue enhancing agents and/or adipose tissue, new tissue within the convex shaped void grows until a balance is achieved eliminating the induced stress. Periodically the tissue expansion devices is again activated and enlarged creating an even larger void. Again, the newly enlarged void places additional tensile stress on the underlying tissue thus repeating the cycle of new tissue growth. Once the desired amount of tissue growth has been achieved the device is deactivated and removed.

Abstract translation: 在期望的组织生长区域上植入非活化状态的组织扩张装置。 一旦植入和定位，器件被激活，产生支撑结构，该支撑结构在下面的组织上形成凸形的圆顶。 由组织膨胀装置形成的凸形圆顶对促进组织生长的下面的组织施加拉伸应力。 单独或随着组织增强剂和/或脂肪组织的引入，凸形空隙内的新组织生长直到达到平衡而消除诱导的应力。 定期地，组织膨胀装置再次被激活和扩大，从而产生更大的空隙。 再次，新扩大的空隙在下面的组织上施加额外的拉伸应力，从而重复新组织生长的循环。 一旦实现了所需量的组织生长，该装置被去活和去除。

公开(公告)号：US08858628B2

公开(公告)日：2014-10-14

申请号：US11957083

申请日：2007-12-14

Applicant: Gino Rigotti ,  Guido Baroni

Inventor： Gino Rigotti ,  Guido Baroni

IPC: A61F2/12 ,  A61H9/00

CPC classification number: A61F2/12 ,  A61B90/02 ,  A61F2250/0003 ,  A61H9/005

Abstract: A tissue expansion device implanted in a non-activated state over a region of desired tissue growth. Once implanted and positioned the device is activated creating a supporting structure that creates a convex shaped dome over the underlying tissue. The convex shaped dome formed by the tissue expansion device places a tensile stress against the underlying tissue that promotes tissue growth. Alone or with the introduction of tissue enhancing agents and/or adipose tissue, new tissue within the convex shaped void grows until a balance is achieved eliminating the induced stress. Periodically the tissue expansion devices is again activated and enlarged creating an even larger void. Again, the newly enlarged void places additional tensile stress on the underlying tissue thus repeating the cycle of new tissue growth. Once the desired amount of tissue growth has been achieved the device is deactivated and removed.

Abstract translation: 在期望的组织生长区域上植入非活化状态的组织扩张装置。 一旦植入和定位，器件被激活，产生支撑结构，该支撑结构在下面的组织上形成凸形的圆顶。 由组织膨胀装置形成的凸形圆顶对促进组织生长的下面的组织施加拉伸应力。 单独或随着组织增强剂和/或脂肪组织的引入，凸形空隙内的新组织生长直到达到平衡而消除诱导的应力。 定期地，组织膨胀装置再次被激活和扩大，从而产生更大的空隙。 再次，新扩大的空隙在下面的组织上施加额外的拉伸应力，从而重复新组织生长的循环。 一旦实现了所需量的组织生长，该装置被去活和去除。

公开(公告)号：US08821573B2

公开(公告)日：2014-09-02

申请号：US13390453

申请日：2012-02-11

Applicant: Roger K Khouri ,  Gino Rigotti ,  Guido Baroni

Inventor： Roger K Khouri ,  Gino Rigotti ,  Guido Baroni

IPC: A61F2/12 ,  A61H7/00 ,  A61H9/00

CPC classification number: A61F2/12 ,  A61H7/00 ,  A61H9/0057 ,  A61H2201/165 ,  A61H2205/082

Abstract: A device for maintaining or achieving soft tissue expansion applicable to any body region already temporarily expanded including: an adhesive element deformable and capable of adapting to the shape of this body region, and which can then itself become mechanically rigid enough to resist tendency of the expanded tissue to recoil or to which a second material can be applied to form a stent adapted to the shape of the body area to provide the necessary structural rigidity to prevent recoil of the expansion and thereby induce its retention of its expanded shape after the stent is removed.

Abstract translation: 一种用于维持或实现适用于已经暂时扩大的任何身体区域的软组织膨胀的装置，包括：可变形并且能够适应该身体区域的形状的粘合元件，其然后可以自身变得机械刚性足以抵抗膨胀的趋势 组织反冲或可以施加第二材料以形成适合于身体区域形状的支架，以提供必要的结构刚度以防止膨胀反冲，从而在支架被移除之后引起其扩张形状的保持 。

公开(公告)号：US20080300681A1

公开(公告)日：2008-12-04

申请号：US11957083

申请日：2007-12-14

Applicant: Gino Rigotti ,  Guido Baroni

Inventor： Gino Rigotti ,  Guido Baroni

IPC: A61F2/12

CPC classification number: A61F2/12 ,  A61B90/02 ,  A61F2250/0003 ,  A61H9/005

Abstract: A tissue expansion device implanted in a non-activated state over a region of desired tissue growth. Once implanted and positioned the device is activated creating a supporting structure that creates a convex shaped dome over the underlying tissue. The convex shaped dome formed by the tissue expansion device places a tensile stress against the underlying tissue that promotes tissue growth. Alone or with the introduction of tissue enhancing agents and/or adipose tissue, new tissue within the convex shaped void grows until a balance is achieved eliminating the induced stress. Periodically the tissue expansion devices is again activated and enlarged creating an even larger void. Again, the newly enlarged void places additional tensile stress on the underlying tissue thus repeating the cycle of new tissue growth. Once the desired amount of tissue growth has been achieved the device is deactivated and removed.

Abstract translation: 在期望的组织生长区域上植入非活化状态的组织扩张装置。 一旦植入和定位，器件被激活，产生支撑结构，该支撑结构在下面的组织上形成凸形的圆顶。 由组织膨胀装置形成的凸形圆顶对促进组织生长的下面的组织施加拉伸应力。 单独或随着组织增强剂和/或脂肪组织的引入，凸形空隙内的新组织生长直到达到平衡而消除诱导的应力。 定期地，组织膨胀装置再次被激活和扩大，从而产生更大的空隙。 再次，新扩大的空隙在下面的组织上施加额外的拉伸应力，从而重复新组织生长的循环。 一旦实现了所需量的组织生长，该装置被去活和去除。

公开(公告)号：US08496702B2

公开(公告)日：2013-07-30

申请号：US12714349

申请日：2010-02-26

Applicant: Gino Rigotti ,  Guido Baroni

Inventor： Gino Rigotti ,  Guido Baroni

IPC: A61F2/12

CPC classification number: A61F2/12 ,  A61B90/02 ,  A61F2250/0003 ,  A61H9/005

Abstract: A tissue expansion device implanted in a non-activated state over a region of desired tissue growth. Once implanted and positioned the device is activated creating a supporting structure that creates a convex shaped dome over the underlying tissue. The convex shaped dome formed by the tissue expansion device places a tensile stress against the underlying tissue that promotes tissue growth. Alone or with the introduction of tissue enhancing agents and/or adipose tissue, new tissue within the convex shaped void grows until a balance is achieved eliminating the induced stress. Periodically the tissue expansion devices is again activated and enlarged creating an even larger void. Again, the newly enlarged void places additional tensile stress on the underlying tissue thus repeating the cycle of new tissue growth. Once the desired amount of tissue growth has been achieved the device is deactivated and removed.

Abstract translation: 在期望的组织生长区域上植入非活化状态的组织扩张装置。 一旦植入和定位，器件被激活，产生支撑结构，该支撑结构在下面的组织上形成凸形的圆顶。 由组织膨胀装置形成的凸形圆顶对促进组织生长的下面的组织施加拉伸应力。 单独或随着组织增强剂和/或脂肪组织的引入，凸形空隙内的新组织生长直到达到平衡而消除诱导的应力。 定期地，组织膨胀装置再次被激活和扩大，从而产生更大的空隙。 再次，新扩大的空隙在下面的组织上施加额外的拉伸应力，从而重复新组织生长的循环。 一旦实现了所需量的组织生长，该装置被去活和去除。

公开(公告)号：US20090181104A1

公开(公告)日：2009-07-16

申请号：US12334140

申请日：2008-12-12

Applicant: Gino Rigotti ,  Guido Baroni

Inventor： Gino Rigotti ,  Guido Baroni

IPC: A61K35/36 ,  A01N1/02

CPC classification number: A61F2/12 ,  A61B2017/00969 ,  A61K35/35 ,  A61M2202/08

Abstract: A tissue transfer method for reconstruction and augmentation of soft tissue. The method includes harvesting adipose tissue from a patient. The harvested tissue is processed via centrifugation to isolate a purified subset of the adipose tissue including separating and removing a substantial amount of triglycerides from the harvested adipose tissue. The centrifugation may be performed to cause separation of water from the purified adipose tissue and to cause separation of oil from mature adipocytes. Specifically, the spin rates may be selected to be high enough to cause lesions in the mature adipocytes that results in the release of the oil. The method continues with implanting the purified adipose tissue into the patient at a breast or other area identified for reconstruction or augmentation. The implanting is performed based on an injection pathway model that defines injection point locations and a number of injection pathway directions from each point.

Abstract translation: 一种用于重建和增加软组织的组织移植方法。 该方法包括从患者收获脂肪组织。 通过离心处理收获的组织以分离纯化的脂肪组织亚组，包括从收获的脂肪组织中分离并除去大量的甘油三酯。 可以进行离心以使来自纯化的脂肪组织的水分离并引起油从成熟脂肪细胞分离。 具体地说，旋转速率可被选择为足够高以引起成熟脂肪细胞中导致油释放的损伤。 该方法继续将经纯化的脂肪组织植入到确定用于重建或增大的乳房或其他区域的患者体内。 基于从每个点限定注射点位置和多个注射通道方向的注射通路模型进行注入。

公开(公告)号：US08480735B2

公开(公告)日：2013-07-09

申请号：US12714293

申请日：2010-02-26

Applicant: Gino Rigotti ,  Guido Baroni

Inventor： Gino Rigotti ,  Guido Baroni

IPC: A61F2/12

CPC classification number: A61F2/12 ,  A61B90/02 ,  A61F2250/0003 ,  A61H9/005

Abstract: A tissue expansion device implanted in a non-activated state over a region of desired tissue growth. Once implanted and positioned the device is activated creating a supporting structure that creates a convex shaped dome over the underlying tissue. The convex shaped dome formed by the tissue expansion device places a tensile stress against the underlying tissue that promotes tissue growth. Alone or with the introduction of tissue enhancing agents and/or adipose tissue, new tissue within the convex shaped void grows until a balance is achieved eliminating the induced stress. Periodically the tissue expansion devices is again activated and enlarged creating an even larger void. Again, the newly enlarged void places additional tensile stress on the underlying tissue thus repeating the cycle of new tissue growth. Once the desired amount of tissue growth has been achieved the device is deactivated and removed.

Abstract translation: 在期望的组织生长区域上植入非活化状态的组织扩张装置。 一旦植入和定位，器件被激活，产生支撑结构，该支撑结构在下面的组织上形成凸形的圆顶。 由组织膨胀装置形成的凸形圆顶对促进组织生长的下面的组织施加拉伸应力。 单独或随着组织增强剂和/或脂肪组织的引入，凸形空隙内的新组织生长直到达到平衡而消除诱导的应力。 定期地，组织膨胀装置再次被激活和扩大，从而产生更大的空隙。 再次，新扩大的空隙在下面的组织上施加额外的拉伸应力，从而重复新组织生长的循环。 一旦实现了所需量的组织生长，该装置被去活和去除。

公开(公告)号：US20130046383A1

公开(公告)日：2013-02-21

申请号：US13390453

申请日：2012-02-11

Applicant: Roger K Khouri ,  Gino Rigotti ,  Guido Baroni

Inventor： Roger K Khouri ,  Gino Rigotti ,  Guido Baroni

IPC: A61F2/12 ,  A61H7/00

CPC classification number: A61F2/12 ,  A61H7/00 ,  A61H9/0057 ,  A61H2201/165 ,  A61H2205/082

Abstract: A device for maintaining or achieving soft tissue expansion applicable to any body region already temporarily expanded including: an adhesive element deformable and capable of adapting to the shape of this body region, and which can then itself become mechanically rigid enough to resist tendency of the expanded tissue to recoil or to which a second material can be applied to form a stent adapted to the shape of the body area to provide the necessary structural rigidity to prevent recoil of the expansion and thereby induce its retention of its expanded shape after the stent is removed.

Abstract translation: 一种用于维持或实现适用于已经暂时扩大的任何身体区域的软组织膨胀的装置，包括：可变形并且能够适应该身体区域的形状的粘合元件，其然后可以自身变得机械刚性足以抵抗膨胀的趋势 组织反冲或可以施加第二材料以形成适合于身体区域形状的支架，以提供必要的结构刚度以防止膨胀反冲，从而在支架被移除之后引起其扩张形状的保持 。