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公开(公告)号：US11981914B2
公开(公告)日：2024-05-14
申请号：US18372334
申请日：2023-09-25
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry
IPC: C12N15/864 , A61K48/00 , C07K14/005 , C12N7/00 , C12N9/22 , C12N15/11 , C12N15/86
CPC classification number: C12N15/86 , C07K14/005 , A61K48/00 , C12N2750/14122 , C12N2750/14143
Abstract: AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein are described. Also described are methods of administering the virus vectors and virus capsids to a cell or to a subject in vivo.
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公开(公告)号：US11976096B2
公开(公告)日：2024-05-07
申请号：US18372833
申请日：2023-09-26
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry
IPC: C07K14/005 , A61K31/7088 , A61K38/46 , A61K48/00 , A61P1/16 , C12N7/00 , C12N15/86
CPC classification number: C07K14/005 , A61K31/7088 , A61K38/465 , A61P1/16 , C12N7/00 , C12N15/86 , A61K48/00 , C12N2750/14122 , C12N2750/14143 , C12N2750/14171
Abstract: The present disclosure provides recombinant AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the recombinant AAV capsid proteins. The disclosure also provides methods of administering the virus vectors and vims capsids of the disclosure to a cell or to a subject in vivo.
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公开(公告)号：US20240067986A1
公开(公告)日：2024-02-29
申请号：US18372334
申请日：2023-09-25
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry
IPC: C12N15/86 , C07K14/005
CPC classification number: C12N15/86 , C07K14/005 , A61K48/00
Abstract: AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein are described. Also described are methods of administering the virus vectors and virus capsids to a cell or to a subject in vivo.
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公开(公告)号：US20240059742A1
公开(公告)日：2024-02-22
申请号：US18372823
申请日：2023-09-26
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry , James Kennon Smith
CPC classification number: C07K14/015 , C07K14/4707 , C12N7/00 , C12N9/22 , C12N15/11 , C12N15/86 , A61K38/00
Abstract: The present disclosure provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The disclosure also provides methods of administering the vims vectors and virus capsids of the disclosure to a cell or to a subject in vivo.
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Patent Agency Ranking
公开(公告)号：US12116384B2
公开(公告)日：2024-10-15
申请号：US17045087
申请日：2019-04-03
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry
IPC: C07K14/005 , C12N9/22 , C12N15/11 , C12N15/86 , A61K48/00
CPC classification number: C07K14/005 , C12N9/22 , C12N15/11 , C12N15/86 , A61K48/00 , C12N2310/20 , C12N2750/14122 , C12N2750/14143 , C12N2750/14145 , C12N2800/80
Abstract: The present disclosure provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The disclosure also provides methods of administering the virus vectors and virus capsids of the disclosure to a cell or to a subject in vivo.
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公开(公告)号：US12091435B2
公开(公告)日：2024-09-17
申请号：US17045090
申请日：2019-04-03
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry , James Kennon Smith
IPC: C12N9/22 , C07K14/005 , C07K14/015 , C07K14/47 , C12N7/00 , C12N15/11 , C12N15/86 , A61K38/00
CPC classification number: C07K14/015 , C07K14/005 , C07K14/4707 , C12N7/00 , C12N9/22 , C12N15/11 , C12N15/86 , A61K38/00 , C12N2750/14122 , C12N2750/14143
Abstract: The present disclosure provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The disclosure also provides methods of administering the virus vectors and virus capsids of the disclosure to a cell or to a subject in vivo.
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公开(公告)号：US12060390B2
公开(公告)日：2024-08-13
申请号：US18372823
申请日：2023-09-26
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry , James Kennon Smith
IPC: C07K14/005 , C07K14/015 , C07K14/47 , C12N7/00 , C12N9/22 , C12N15/11 , C12N15/86 , A61K38/00
CPC classification number: C07K14/015 , C07K14/005 , C07K14/4707 , C12N7/00 , C12N9/22 , C12N15/11 , C12N15/86 , A61K38/00 , C12N2750/14122 , C12N2750/14143
Abstract: The present disclosure provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The disclosure also provides methods of administering the virus vectors and virus capsids of the disclosure to a cell or to a subject in vivo.
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公开(公告)号：US11905523B2
公开(公告)日：2024-02-20
申请号：US17072624
申请日：2020-10-16
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry , David Dismuke
IPC: C12N15/861 , C07K14/47 , A61K48/00 , C12N15/86 , A61P3/00 , C07K14/005 , C12N7/00 , A61K38/00
CPC classification number: C12N15/86 , A61P3/00 , C07K14/005 , C07K14/47 , C12N7/00 , A61K38/00 , C12N2750/14122 , C12N2750/14143 , C12N2830/50
Abstract: Provided herein are gene therapy compositions and methods for treating, preventing, and/or curing NPC1. More specifically, the disclosure provides Adeno-associated virus (AAV) vectors for delivery of nucleic acids and nucleic acids (including AAV transfer cassettes) for treating, preventing, and/or curing NPC1.
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公开(公告)号：US20240051998A1
公开(公告)日：2024-02-15
申请号：US18372833
申请日：2023-09-26
Applicant: Ginkgo Bioworks, Inc.
Inventor： Daniel McCoy , Garrett E. Berry
IPC: C07K14/005 , A61P1/16 , A61K31/7088 , A61K38/46 , C12N7/00 , C12N15/86
CPC classification number: C07K14/005 , A61P1/16 , A61K31/7088 , A61K38/465 , C12N7/00 , C12N15/86 , A61K48/00
Abstract: The present disclosure provides recombinant AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the recombinant AAV capsid proteins. The disclosure also provides methods of administering the virus vectors and vims capsids of the disclosure to a cell or to a subject in vivo.
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