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公开(公告)号：US12053517B2
公开(公告)日：2024-08-06
申请号：US17574465
申请日：2022-01-12
发明人： Jiani Li , Xinan Liu , Azure T. Makadzange , Stephen R. Martin , Hesham Shehata , Evguenia Svarovskaia
IPC分类号： A61K39/12 , A61P31/18 , C07K14/005 , C07K16/10 , C07K16/28 , C12N15/10 , C12N15/86 , A61K39/00
CPC分类号： A61K39/12 , A61P31/18 , C07K14/005 , C07K16/1045 , C07K16/2818 , C07K16/2827 , C12N15/1082 , C12N15/86 , A61K2039/53 , A61K2039/70 , C12N2710/10343 , C12N2710/16143 , C12N2740/15034 , C12N2740/16022 , C12N2740/16034 , C12N2740/16134 , C12N2740/16234 , C12N2760/10043
摘要： Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.
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公开(公告)号：US20240117017A1
公开(公告)日：2024-04-11
申请号：US18468515
申请日：2023-09-15
CPC分类号： C07K16/1045 , A61K9/14 , A61K45/06 , C07K16/2818 , C07K16/2827 , C12N15/1082
摘要： Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.
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公开(公告)号：US11795210B2
公开(公告)日：2023-10-24
申请号：US16928571
申请日：2020-07-14
CPC分类号： C07K16/1045 , A61K9/14 , A61K45/06 , C07K16/2818 , C07K16/2827 , C12N15/1082
摘要： Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.
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公开(公告)号：US20220218813A1
公开(公告)日：2022-07-14
申请号：US17574465
申请日：2022-01-12
发明人： Jiani Li , Xinan Liu , Azure T. Makadzange , Stephen R. Martin , Sarah Schmidt , Hesham Shehata , Felix Stemeseder , Evguenia Svarovskaia , Archana V. Boopathy
摘要： Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.
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公开(公告)号：US20210017255A1
公开(公告)日：2021-01-21
申请号：US16928571
申请日：2020-07-14
摘要： Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.
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