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公开(公告)号：US20230212155A1
公开(公告)日：2023-07-06
申请号：US18060934
申请日：2022-12-01
发明人： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC分类号： C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00
CPC分类号： C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00 , C07K16/2818
摘要： Compounds of Formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US20210024494A1
公开(公告)日：2021-01-28
申请号：US16923750
申请日：2020-07-08
发明人： Evangelos Aktoudianakis , Aesop Cho , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Devan Naduthambi , Barton W. Phillips , Scott Preston Simonovich , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC分类号： C07D401/14 , A61K31/444 , A61K31/497 , A61K31/704 , A61K31/7068 , A61K39/395 , C07D471/08
摘要： Compounds and methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US20200157094A1
公开(公告)日：2020-05-21
申请号：US16660219
申请日：2019-10-22
发明人： Zhimin Du , Michael Graupe , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Eric Q. Parkhill , Barton W. Phillips , Scott P. Simonovich , Peiyuan Wang , Jie Xu , Christopher A. Ziebenhaus
IPC分类号： C07D471/04 , C07D513/04 , C07D401/12 , C07D413/10 , C07D217/04 , C07D401/14 , C07D471/08 , C07D487/04 , C07D495/04
摘要： Compounds and methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US11555029B2
公开(公告)日：2023-01-17
申请号：US16891880
申请日：2020-06-03
发明人： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC分类号： C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00 , C07K16/28
摘要： Compounds of Formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US20210053946A1
公开(公告)日：2021-02-25
申请号：US16891880
申请日：2020-06-03
发明人： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC分类号： C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00
摘要： Compounds of Formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US10899735B2
公开(公告)日：2021-01-26
申请号：US16388517
申请日：2019-04-18
申请人： Gilead Sciences, Inc
发明人： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC分类号： C07D401/10 , A61K31/444 , C07D401/04 , C07D401/12 , C07D401/14 , C07D487/10 , C07D519/00 , C07K16/28
摘要： Compounds and methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US20200017471A1
公开(公告)日：2020-01-16
申请号：US16510647
申请日：2019-07-12
发明人： Evangelos Aktoudianakis , Aesop Cho , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Devan Naduthambi , Barton W. Phillips , Scott Preston Simonovich , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC分类号： C07D401/14 , C07D471/08 , A61K39/395 , A61K31/704 , A61K31/7068 , A61K31/444 , A61K31/497
摘要： Compounds and methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US20190270727A1
公开(公告)日：2019-09-05
申请号：US16274106
申请日：2019-02-12
发明人： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC分类号： C07D403/14 , A61P35/02 , A61P31/20 , C07D519/00 , A61K31/496
摘要： Compounds of Formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US20180305315A1
公开(公告)日：2018-10-25
申请号：US15957739
申请日：2018-04-19
发明人： Evangelos Aktoudianakis , Todd Appleby , Aesop Cho , Zhimin Du , Michael Graupe , Juan A. Guerrero , Salman Y. Jabri , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Gregory Notte , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Chandrasekar Venkataramani , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC分类号： C07D213/69 , A61K45/06 , A61K31/444 , C07D401/14 , A61K31/4545 , C07D213/85 , A61K31/44 , C07D213/30 , C07D295/088 , A61K31/5377
CPC分类号： C07D213/69 , A61K31/44 , A61K31/444 , A61K31/4545 , A61K31/497 , A61K31/5377 , A61K45/06 , C07D213/30 , C07D213/61 , C07D213/64 , C07D213/85 , C07D295/088 , C07D401/04 , C07D401/14 , C07D405/14 , C07D487/08 , C07D487/10 , C07D491/107 , C07D498/04 , C07D519/00
摘要： Compounds according to formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US11236085B2
公开(公告)日：2022-02-01
申请号：US16660219
申请日：2019-10-22
发明人： Zhimin Du , Michael Graupe , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Eric Q. Parkhill , Barton W. Phillips , Scott P. Simonovich , Peiyuan Wang , Jie Xu , Christopher A. Ziebenhaus
IPC分类号： C07D471/04 , C07D217/04 , C07D401/12 , C07D401/14 , C07D413/10 , C07D471/08 , C07D487/04 , C07D495/04 , C07D513/04 , C07K16/28 , C07K16/40
摘要： Compounds and methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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