Abstract:
A computer-implemented method for penalized-likelihood reconstruction of a Positron Emission Tomography (PET) image includes generating a regularization function in which a smoothing parameter is modulated by one or more data-independent spatially variable modulation factors to compensate for sensitivity variations in a PET voxel dataset, and reconstructing the PET image from the PET emission dataset using the regularization function.
Abstract:
A computer-implemented method for partial volume correction in Positron Emission Tomography (PET) image reconstruction includes receiving emission data related to an activity distribution, reconstructing the activity distribution from the emission data by maximizing a penalized-likelihood objective function to produce a reconstructed PET image, quantifying an activity concentration in a region of interest of the reconstructed PET image to produce an uncorrected quantitation, and correcting the uncorrected quantitation based on a pre-calculated contrast recovery coefficient value to account for a partial volume error in the uncorrected quantitation.
Abstract:
A computer-implemented method for penalized-likelihood reconstruction of a Positron Emission Tomography (PET) image includes generating a regularization function in which a smoothing parameter is modulated by one or more data-independent spatially variable modulation factors to compensate for sensitivity variations in a PET voxel dataset, and reconstructing the PET image from the PET emission dataset using the regularization function.
Abstract:
A computer-implemented method for partial volume correction in Positron Emission Tomography (PET) image reconstruction includes receiving emission data related to an activity distribution, reconstructing the activity distribution from the emission data by maximizing a penalized-likelihood objective function to produce a reconstructed PET image, quantifying an activity concentration in a region of interest of the reconstructed PET image to produce an uncorrected quantitation, and correcting the uncorrected quantitation based on a pre-calculated contrast recovery coefficient value to account for a partial volume error in the uncorrected quantitation.