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1.
公开(公告)号:US20150203581A1
公开(公告)日:2015-07-23
申请号:US14593950
申请日:2015-01-09
Applicant: GENENTECH, INC.
Inventor: Wei-Ching LIANG , Gregory D. PLOWMAN , Yan WU , Weilan YE
CPC classification number: C07K16/2842 , A61K47/6835 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K2317/24 , C07K2317/31 , C07K2317/56 , C07K2317/565 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412
Abstract: The present invention provides new anti-α5β1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.
Abstract translation: 本发明提供新的抗α5和bgr1抗体,包含抗体的组合物和试剂盒,以及制备和使用抗体的方法。
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2.TREATMENT OF DISORDERS WITH ALTERED VASCULAR BARRIER FUNCTION 审中-公开
Title translation: 用改进的血管阻滞功能治疗疾病公开(公告)号:US20150366930A1
公开(公告)日:2015-12-24
申请号:US14604556
申请日:2015-01-23
Applicant: Genentech, Inc.
Inventor: Weilan YE , Leon H. PARKER , Christopher W. WILSON
IPC: A61K38/02 , C12N15/113
CPC classification number: A61K38/02 , A61K31/00 , A61K31/7105 , C12N15/113
Abstract: The present invention provides methods of using RASIP1 agonists and antagonists to modulate vascular barrier function and regulate new vessel formation, and to treat related disorders.
Abstract translation: 本发明提供了使用RASIP1激动剂和拮抗剂调节血管屏障功能并调节新血管形成以及治疗相关疾病的方法。
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3.
公开(公告)号:US20150093375A1
公开(公告)日:2015-04-02
申请号:US14262368
申请日:2014-04-25
Applicant: Genentech, Inc.
Inventor: Harald J. JUNGE , Weilan YE
IPC: C07K16/28 , A61K38/17 , C07K16/18 , A61K39/395 , C07K14/705 , A61K45/06
CPC classification number: C07K16/28 , A61K38/177 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/705 , C07K16/18 , C07K16/22 , C07K2317/34 , C07K2317/76
Abstract: The present invention provides methods of using TSPAN12 and Norrin antagonists to inhibit ocular vascular development and to treat related disorders.
Abstract translation: 本发明提供了使用TSPAN12和Norrin拮抗剂抑制眼血管发育和治疗相关疾病的方法。
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公开(公告)号:US20130324704A1
公开(公告)日:2013-12-05
申请号:US13944538
申请日:2013-07-17
Applicant: Genentech, Inc.
Inventor: Weilan YE , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/22
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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5.
公开(公告)号:US20130287779A1
公开(公告)日:2013-10-31
申请号:US13919629
申请日:2013-06-17
Applicant: Genentech, Inc.
Inventor: Weilan YE , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/46 , A61K45/06 , A61K39/395 , A61K31/519 , A61K31/282 , A61K31/337 , C07K16/22 , A61K31/513
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
Abstract translation: 本发明涉及EGFL7的抗体及其用途。
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公开(公告)号:US20130129735A1
公开(公告)日:2013-05-23
申请号:US13755950
申请日:2013-01-31
Applicant: Genentech, Inc.
Inventor: Weilan YE , Maike Schmidt , Jo-Anne Hongo , Yan Wu
IPC: A61K39/395 , A61K45/06 , C07K16/22
CPC classification number: C07K16/22 , A61K2039/505 , A61K2039/507 , C07K2317/56 , C07K2317/565 , C07K2317/73
Abstract: The invention provides anti-EGFL7 antibodies, and compositions comprising and methods of using these antibodies.
Abstract translation: 本发明提供抗EGFL7抗体,以及组合物和使用这些抗体的方法。
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