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公开(公告)号:US20220098325A1
公开(公告)日:2022-03-31
申请号:US17473401
申请日:2021-09-13
Applicant: Genentech, Inc.
Inventor: Teemu T. JUNTTILA , Stuart LUTZKER
IPC: C07K16/32 , A61P35/00 , C07K16/28 , A61K45/06 , A61K39/395
Abstract: The present invention provides methods of treating of HER2-positive cancers (such as HER2-positive breast cancer and HER2-positive gastric cancers) using HER2 antibodies, such as a combination of a HER2 T cell-dependent bispecific antibody (TDB) with an additional HER2 antibody (e.g., trastuzumab).