公开(公告)号：US20220348687A1

公开(公告)日：2022-11-03

申请号：US17761727

申请日：2020-09-18

Applicant: Genentech, Inc.

Inventor： Joseph Haw-Ling LIN ,  Ryan Patrick OWEN ,  Sharon Marie RYMUT ,  Siddharth SUKUMARAN

IPC: C07K16/40 ,  A61P11/06

Abstract: The present invention features, inter alia, methods of treating a patient having asthma by administering an anti-tryptase antibody (e.g., anti-tryptase beta antibody) to the patient, anti-tryptase antibodies (e.g., anti-tryptase beta antibodies) for use in treating asthma, and uses of anti-tryptase antibodies (e.g., anti-tryptase beta antibodies), e.g., in the manufacture of medicaments for treating asthma.

公开(公告)号：US20240270873A1

公开(公告)日：2024-08-15

申请号：US18438661

申请日：2024-02-12

Applicant: Genentech, Inc.

Inventor： Sara Beth GLICKSTEIN BAR-ZEEV ,  Horace H. RHEE ,  Sharon Marie RYMUT ,  Tracy Lyn STATON ,  Kenta YOSHIDA ,  David Fong CHOY

IPC: C07K16/40 ,  A61K9/00 ,  A61K39/00 ,  A61K45/06 ,  A61P17/04

CPC classification number: C07K16/40 ,  A61K9/0019 ,  A61K45/06 ,  A61P17/04 ,  A61K2039/505 ,  A61K2039/545 ,  C07K2317/565

Abstract: The present invention features, inter alia, methods of treating a patient having chronic spontaneous urticaria (CSU) by administering an anti-tryptase antibody (e.g., anti-tryptase beta antibody) to the patient, anti-tryptase antibodies (e.g., anti-tryptase beta antibodies) for use in treating CSU, and uses of anti-tryptase antibodies (e.g., anti-tryptase beta antibodies), e.g., in the manufacture of medicaments for treating CSU.