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公开(公告)号:US10208120B2
公开(公告)日:2019-02-19
申请号:US14934059
申请日:2015-11-05
Applicant: Genentech, Inc.
Inventor: Yiyuan Yin , Avi Ashkenazi , Paul J. Carter , Mark Chen , Junichiro Sonoda
Abstract: The invention provides dual specific anti-FGFR2 and FGFR3 (FGFR2/3) antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号:US09937224B2
公开(公告)日:2018-04-10
申请号:US14822711
申请日:2015-08-10
Applicant: Genentech, Inc.
Inventor: Ryan J. Watts , Mark Chen , Joseph Wesley Lewcock , Christine Pozniak , Arundhati Sengupta-Ghosh
IPC: A61K39/395 , A61K33/14 , A61K31/40 , A61K38/12 , A61K31/7088 , A61K31/711 , C12N15/113 , A61K31/7105 , A61K31/277 , A61K31/35 , A61K31/4015 , A61K31/416 , A61K31/4439 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K38/05 , A61K38/18 , C07K16/22 , G01N33/50 , A61K31/12 , A61K31/165 , A61K31/352 , A61K31/4184 , A61K31/426 , A61K31/433 , A61K31/45 , A61K31/496 , A61K31/505 , A61K31/517 , A61K31/519 , A61K31/713 , C07K16/40
CPC classification number: A61K38/12 , A61K31/12 , A61K31/165 , A61K31/277 , A61K31/35 , A61K31/352 , A61K31/40 , A61K31/4015 , A61K31/416 , A61K31/4184 , A61K31/426 , A61K31/433 , A61K31/4439 , A61K31/45 , A61K31/496 , A61K31/505 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/52 , A61K31/5377 , A61K31/7088 , A61K31/7105 , A61K31/711 , A61K31/713 , A61K33/14 , A61K38/05 , A61K38/185 , C07K16/22 , C07K16/40 , C07K2317/76 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2320/30 , G01N33/5058
Abstract: The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to modulate degeneration of neurons or portions thereof, such as axons.
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