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公开(公告)号：US20190062444A1
公开(公告)日：2019-02-28
申请号：US16021480
申请日：2018-06-28
Applicant: Genentech, Inc.
Inventor： Kevin Walsh , Patricia De Almeida , Changchun Du , Jeong Kim , Jing Zhu , Jack Bevers, III , James Andya , Ye Shen
Abstract: The invention provides compositions and methods for treating cancers. The method comprises administering an anti-angiogenesis agent and an OX40 binding agonist.
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公开(公告)号：US11555076B2
公开(公告)日：2023-01-17
申请号：US16345619
申请日：2017-10-27
Applicant: Genentech, Inc.
Inventor： Twyla Noelle Lombana , Christoph Spiess , Jeong Kim , Evangeline Toy , Jill Schartner , Zhengmao Ye , Jack Bevers, III , Ryan Cook , Marissa Matsumoto , Amy Berkley
Abstract: The invention provides anti-MIC antibodies and methods of using the same.
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公开(公告)号：US10570213B2
公开(公告)日：2020-02-25
申请号：US15167125
申请日：2016-05-27
Applicant: Genentech, Inc.
Inventor： Jeong Kim , Jeanne Cheung
IPC: C07K16/28 , A61K39/395 , C07K16/32 , A61K31/337 , A61K45/06 , A61K31/282 , C07K16/30 , A61K39/00
Abstract: The invention provides methods and compositions for treating cancer and for enhancing immune function in an individual having cancer. The methods comprise administering a PD-1 axis binding antagonist and a taxane.
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Patent Agency Ranking
4.发明申请USE OF CBP/EP300 BROMODOMAIN INHIBITORS FOR CANCER IMMUNOTHERAPY 审中-公开CBP / EP300 BROMODOMAIN抑制剂用于癌症免疫治疗的用途公开(公告)号：US20160317632A1
公开(公告)日：2016-11-03
申请号：US15095985
申请日：2016-04-11
Applicant: GENENTECH, INC. , CONSTELLATION PHARMACEUTICALS, INC.
Inventor： Brian K. Albrecht , James Edmund Audia , Steven Bellon , Andrea Cochran , Alexandre Cote , Terry Crawford , Benjamin Fauber , Srimoyee Ghosh , Jean-Christophe Harmange , Georgia Hatzivassiliou , Hariharan Jayaram , Jeong Kim , Jose M. Lora , Steven Magnuson , Ira Mellman , Anthony F. Romero , Alexander M. Taylor , Vickie Tsui
IPC: A61K39/00 , A61K31/498 , G01N33/50 , A61K31/538
CPC classification number: A61K39/0011 , A61K31/498 , A61K31/538 , C07K14/475 , G01N33/5011
Abstract: The present invention relates to use of CBP/EP300 bromodomain inhibitors for the treatment of cancer.
Abstract translation: 本发明涉及CBP / EP300溴结构域抑制剂用于治疗癌症的用途。
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公开(公告)号：US11046776B2
公开(公告)日：2021-06-29
申请号：US15669861
申请日：2017-08-04
Applicant: Genentech, Inc.
Inventor： Greg Lazar , Yanli Yang , Erin H. Christensen , Julie Hang , Jeong Kim , Seth Harris
IPC: A61K39/395 , C07K16/28 , A61K45/06 , A61K39/00
Abstract: Provided herein are tetravalent antigen binding complexes having agonist activity for a cell surface receptor. In some embodiments, the complexes comprise binding specificities for multiple epitopes of the same cell surface receptor. Further provided herein are nucleic acids, vectors, host cells, pharmaceutical compositions, and methods of production related thereto.
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公开(公告)号：US10730951B2
公开(公告)日：2020-08-04
申请号：US15951082
申请日：2018-04-11
Applicant: Genentech, Inc.
Inventor： Changchun Du , Jeong Kim , Jing Zhu , Jack Bevers, III , Kevin Walsh , Patricia De Almeida , James Andya , Ye Shen
IPC: C12N5/10 , C12N15/63 , C12N15/70 , C12N15/79 , C07K16/28 , C07K16/30 , C07K16/22 , A61K47/68 , A61K39/395 , A61K45/06 , A61K39/00 , C12N15/64 , A61K48/00
Abstract: The invention provides anti-OX40 antibodies and methods of using the same.
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公开(公告)号：US09975957B2
公开(公告)日：2018-05-22
申请号：US14673792
申请日：2015-03-30
Applicant: Genentech, Inc.
Inventor： Changchun Du , Jeong Kim , Jing Zhu , Jack Bevers, III , Kevin Walsh , Patricia De Almeida , James Andya , Ye Shen
CPC classification number: C07K16/2878 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K48/00 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/71 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-OX40 antibodies and methods of using the same.
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公开(公告)号：US20150307617A1
公开(公告)日：2015-10-29
申请号：US14673792
申请日：2015-03-30
Applicant: Genentech, Inc.
Inventor： Changchun DU , Jeong Kim , Jing Zhu , Jack Bevers, III , Kevin Walsh , Patricia De Almeida , James Andya , Ye Shen
IPC: C07K16/28 , A61K39/395 , C07K16/30 , A61K47/48 , A61K45/06
CPC classification number: C07K16/2878 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K48/00 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/71 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-OX40 antibodies and methods of using the same.
Abstract translation: 本发明提供抗OX40抗体及其使用方法。
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