公开(公告)号：US10124069B2

公开(公告)日：2018-11-13

申请号：US15182429

申请日：2016-06-14

Applicant: Genentech, Inc.

Inventor： Ho Huat Lee ,  Moana Tercel ,  John A. Flygare ,  Janet Gunzner-Toste ,  Thomas H. Pillow ,  Brian Safina ,  Leanna Staben ,  Vishal Verma ,  BinQing Wei ,  Guiling Zhao

IPC: A61K47/00 ,  A61K47/48 ,  C07K16/28 ,  C07K16/30 ,  A61K47/68 ,  A61K39/00

Abstract: This invention relates to peptidomimetic linkers and anti-body drug conjugates thereof, to pharmaceutical compositions containing them, and to their use in therapy for the prevention or treatment of cancer.

公开(公告)号：US20190083643A1

公开(公告)日：2019-03-21

申请号：US16150623

申请日：2018-10-03

Applicant: Genentech, Inc.

Inventor： Ho Huat Lee ,  Moana Tercel ,  John A. Flygare ,  Janet Gunzner-Toste ,  Thomas H. Pillow ,  Brian Safina ,  Leanna Staben ,  Vishal Verma ,  BinQing Wei ,  Guiling Zhao

IPC: A61K47/68 ,  C07K16/28 ,  C07K16/30 ,  A61K39/00

Abstract: This invention relates to peptidomimetic linkers and anti-body drug conjugates thereof, to pharmaceutical compositions containing them, and to their use in therapy for the prevention or treatment of cancer.

公开(公告)号：US20160279261A1

公开(公告)日：2016-09-29

申请号：US15182429

申请日：2016-06-14

Applicant: Ho Huat Lee ,  Moana Tercel ,  Genentech, Inc.

Inventor： Ho Huat Lee ,  Moana Tercel ,  John A. Flygare ,  Janet Gunzner-Toste ,  Thomas H. Pillow ,  Brian Safina ,  Leanna Staben ,  Vishal Verma ,  BinQing Wei ,  Guiling Zhao

IPC: A61K47/48 ,  C07K16/30 ,  C07K16/28

CPC classification number: C07K16/30 ,  A61K47/6803 ,  A61K47/6851 ,  A61K47/6889 ,  A61K2039/505 ,  C07K16/28 ,  C07K16/2851 ,  C07K16/2863 ,  C07K2317/24 ,  C07K2317/56 ,  C07K2317/76

Abstract: This invention relates to peptidomimetic linkers and anti-body drug conjugates thereof, to pharmaceutical compositions containing them, and to their use in therapy for the prevention or treatment of cancer.