公开(公告)号：US20140038959A1

公开(公告)日：2014-02-06

申请号：US13890411

申请日：2013-05-09

Applicant: Genentech, Inc.

Inventor： Klaus P. Hoeflich ,  Hartmut Koeppen ,  Christy Ong

IPC: A61K31/519 ,  A61K45/06

CPC classification number: A61K31/519 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention relates to a method of treating tumors wherein PAK1 is over-expressed or amplified by co-administering a PAK1 inhibitor and a second anti-hyper-proliferative agent

Abstract translation: 本发明涉及一种治疗肿瘤的方法，其中PAK1通过共同施用PAK1抑制剂和第二抗超增殖剂过表达或扩增