公开(公告)号：US20170233750A1

公开(公告)日：2017-08-17

申请号：US15391059

申请日：2016-12-27

申请人： Gene Bridges GmbH

发明人： Youming Zhang ,  Jun Fu ,  Xiaoying Bian ,  Adrian Francis Stewart ,  Rolf Muller

IPC分类号： C12N15/70 ,  A61K35/74 ,  C12N15/52 ,  C07D498/22 ,  C07K7/64 ,  C07G99/00 ,  C07K5/078 ,  C12N9/12 ,  C07D493/04

CPC分类号： C12N15/70 ,  A61K35/74 ,  A61K2035/11 ,  C07D245/02 ,  C07D417/06 ,  C07D493/04 ,  C07D498/22 ,  C07G17/00 ,  C07K5/06139 ,  C07K7/64 ,  C12N9/1288 ,  C12N9/90 ,  C12N9/93 ,  C12N15/52 ,  C12N15/74 ,  C12P17/10 ,  C12P17/181 ,  C12Y207/08007 ,  Y02P20/52

摘要： This invention is related to bacterial engineering and the heterologous expression of useful compounds. In particular, the invention relates to a heterologous host that has been engineered for expression of a gene which is capable of polyketide or non-ribosomal peptide synthesis. Methods of treating cancer are also disclosed.