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    Methods for improved single photon emission computed tomography using exact and stable region of interest reconstructions
    2.
    发明授权
    Methods for improved single photon emission computed tomography using exact and stable region of interest reconstructions 有权
    使用精确和稳定的兴趣重建区域改进单光子发射计算机断层摄影的方法

    公开(公告)号：US08952333B2

    公开(公告)日：2015-02-10

    申请号：US12938303

    申请日：2010-11-02

    申请人： Hengyong Yu ,  Ge Wang ,  Ming Jiang ,  Jiansheng Yang

    发明人： Hengyong Yu ,  Ge Wang ,  Ming Jiang ,  Jiansheng Yang

    IPC分类号： G06T11/00 ,  A61B6/03

    CPC分类号： A61B6/037 ,  G06T11/006 ,  G06T2211/416

    摘要： The present invention provides systems, methods, and devices for improved computed tomography (CT) and, more specifically, to methods for improved single photon computed tomography (SPECT) using exact and stable region of interest (ROI) reconstructions. This technology can be extended across all tomographic modalities. Embodiments provide a method and a system for reconstructing an image from projection data provided by a single photon emission computed tomography scanner comprising: identifying a region of interest in an object; defining an attenuation coefficient and object boundary; computing the generalized Hilbert transform of the data through the defined region of interest and a known subregion; and reconstructing the image with improved temporal resolution at lower radiation doses, wherein the reconstructing comprises performing a reconstruction method that yields an exact and stable reconstruction. Embodiments also provide a method and a system for reconstructing an image from projection data provided by a single photon emission computed tomography scanner comprising: identifying a region of interest in an object; defining an attenuation coefficient and object boundary; and reconstructing the images by minimizing the high order total variation while minimizing the data discrepancy.

    摘要翻译： 本发明提供用于改进计算机断层摄影（CT）的系统，方法和装置，更具体地，涉及使用精确和稳定的感兴趣区域（ROI）重建的改进的单光子计算机断层摄影（SPECT）的方法。 该技术可以跨越所有断层摄影模式进行扩展。 实施例提供了一种用于从由单个光子发射计算机断层摄影扫描仪提供的投影数据重建图像的方法和系统，包括：识别对象中的感兴趣区域; 定义衰减系数和物体边界; 通过所定义的感兴趣区域和已知子区域计算数据的广义希尔伯特变换; 以及在较低辐射剂量下以改进的时间分辨率重建图像，其中所述重建包括执行产生精确和稳定重建的重建方法。 实施例还提供了一种用于从由单个光子发射计算机断层摄影扫描仪提供的投影数据重建图像的方法和系统，包括：识别对象中的感兴趣区域; 定义衰减系数和物体边界; 并通过最小化高阶总变化同时最小化数据差异来重构图像。

    Systems and Methods for Exact or Approximate Cardiac Computed Tomography
    3.
    发明申请
    Systems and Methods for Exact or Approximate Cardiac Computed Tomography 审中-公开
    精确或近似心脏计算机断层扫描的系统和方法

    公开(公告)号：US20100202583A1

    公开(公告)日：2010-08-12

    申请号：US12684267

    申请日：2010-01-08

    申请人： Ge Wang ,  Hengyong Yu

    发明人： Ge Wang ,  Hengyong Yu

    IPC分类号： A61B6/03

    CPC分类号： A61B6/032 ,  A61B6/027 ,  A61B6/037 ,  A61B6/4021 ,  A61B6/466 ,  A61B6/484 ,  A61B6/503 ,  G06T11/006 ,  G06T2211/432

    摘要： A computed tomography (CT) system has a composite scanning mode in which the x-ray focal spot undergoes a circular or more general motion in the vertical plane facing an object to be reconstructed. The x-ray source also rotates along a circular trajectory along a gantry encircling the object. In this way, a series of composite scanning modes are implemented, including a composite-circling scanning (CCS) mode in which the x-ray focal spot undergoes two circular motions: while the x-ray focal spot is rotated on a plane facing a short object to be reconstructed, the x-ray source is also rotated around the object on the gantry plane. In contrast to the saddle curve cone-beam scanning, the CCS mode requires that the x-ray focal spot undergo a circular motion in a plane facing the short object to be reconstructed, while the x-ray source is rotated in the gantry plane. Because of the symmetry of the mechanical rotations and the compatibility with the physiological conditions, this new CCS mode has significant advantages over the saddle curve from perspectives of both engineering implementation and clinical applications.

    摘要翻译： 计算机断层摄影（CT）系统具有复合扫描模式，其中x射线焦点在面向待重建对象的垂直平面中经历圆形或更一般的运动。 X射线源还沿着围绕物体的台架沿着圆形轨迹旋转。 以这种方式，实现了一系列复合扫描模式，包括复合环绕扫描（CCS）模式，其中x射线焦点经历两个圆周运动：当x射线焦斑在面向 待重建的短对象，X射线源也围绕台架平面上的物体旋转。 与鞍形曲线锥束扫描相反，CCS模式要求x射线焦点在面向待重建的短物体的平面中经历圆周运动，而X射线源在台架平面中旋转。 由于机械旋转的对称性和与生理条件的相容性，这种新的CCS模式在工程实施和临床应用的角度方面具有优于鞍形曲线的优点。

    Tomography-Based and MRI-Based Imaging Systems
    4.
    发明申请
    Tomography-Based and MRI-Based Imaging Systems 审中-公开
    基于层析成像和基于MRI的成像系统

    公开(公告)号：US20110142316A1

    公开(公告)日：2011-06-16

    申请号：US12916458

    申请日：2010-10-29

    申请人： Ge Wang ,  Hengyong Yu ,  Otto Zhou ,  Guohuo Cao ,  Erik Ritman ,  Michael Vannier

    发明人： Ge Wang ,  Hengyong Yu ,  Otto Zhou ,  Guohuo Cao ,  Erik Ritman ,  Michael Vannier

    IPC分类号： G06K9/00

    CPC分类号： G06T11/006 ,  G06T2211/424 ,  G06T2211/432

    摘要： Tomography limitations in vivo due to incomplete, inconsistent and intricate measurements require solution of inverse problems. The new strategies disclosed in this application are capable of providing faster data acquisition, higher image quality, lower radiation dose, greater flexibility, and lower system cost. Such benefits can be used to advance research in cardiovascular diseases, regenerative medicine, inflammation, and nanotechnology. The present invention relates to the field of medical imaging. More particularly, embodiments of the invention relate to methods, systems, and devices for imaging, including tomography-based and MRI-based applications. For example, included in embodiments of the invention are compressive sampling based tomosynthesis methods, which have great potential to reduce the overall x-ray radiation dose for a patient. To name a few, compressive sensing based carbon nano-tube based interior tomosynthesis systems, tomography-based dynamic cardiac elastography systems, cardiac elastodynamic biomarkers from interior MR imaging, exact and stable interior ROI reconstructions for radial MRI, and interior reconstruction based ultrafast tomography systems are provided.

    摘要翻译： 由于不完整，不一致和复杂的测量，体内的层析成像限制需要解决逆问题。 本应用中公开的新策略能够提供更快的数据采集，更高的图像质量，更低的辐射剂量，更大的灵活性和更低的系统成本。 这些益处可用于推进心血管疾病，再生医学，炎症和纳米技术的研究。 本发明涉及医学成像领域。 更具体地，本发明的实施例涉及用于成像的方法，系统和装置，包括基于层析摄影和基于MRI的应用。 例如，包括在本发明的实施例中是基于压缩采样的层析合成方法，其具有降低患者的整体X射线辐射剂量的巨大潜力。 仅举几例，基于压缩感应的基于碳纳米管的内部层析合成系统，基于层析成像的动态心脏弹性成像系统，来自内部MR成像的心脏弹性动力学生物标志物，用于径向MRI的精确和稳定的内部ROI重建以及基于内部重建的超快速层析成像系统 被提供。

    Interior tomography and instant tomography by reconstruction from truncated limited-angle projection data
    5.
    发明授权
    Interior tomography and instant tomography by reconstruction from truncated limited-angle projection data 失效
    通过从截断的有限角度投影数据重构，进行内部层析成像和即时断层扫描

    公开(公告)号：US07697658B2

    公开(公告)日：2010-04-13

    申请号：US12362979

    申请日：2009-01-30

    申请人： Ge Wang ,  Yangbo Ye ,  Hengyong Yu

    发明人： Ge Wang ,  Yangbo Ye ,  Hengyong Yu

    IPC分类号： A61B6/03

    CPC分类号： G06T11/006 ,  A61B6/508 ,  G06T2211/416 ,  G06T2211/432 ,  G06T2211/436

    摘要： A system and method for tomographic image reconstruction using truncated limited-angle projection data that allows exact interior reconstruction (interior tomography) of a region of interest (ROI) based on the linear attenuation coefficient distribution of a subregion within the ROI, thereby improving image quality while reducing radiation dosage. In addition, the method includes parallel interior tomography using multiple sources beamed at multiple angles through an ROI and that enables higher temporal resolution.

    摘要翻译： 一种使用截断的有限角度投影数据进行断层图像重建的系统和方法，其基于ROI内的子区域的线性衰减系数分布，允许感兴趣区域（ROI）的精确内部重建（内部层析成像），从而提高图像质量 同时减少辐射剂量。 另外，该方法包括使用通过ROI以多个角度射束的多个源的并行内部层析成像，并且能够实现更高的时间分辨率。

    Exact local computed tomography based on compressive sampling
    6.
    发明授权
    Exact local computed tomography based on compressive sampling 有权
    基于压缩采样的精确局部计算机断层扫描

    公开(公告)号：US08811700B2

    公开(公告)日：2014-08-19

    申请号：US13264834

    申请日：2010-04-15

    申请人： Ge Wang ,  Hengyong Yu

    发明人： Ge Wang ,  Hengyong Yu

    IPC分类号： G06K9/00

    CPC分类号： G06T11/006 ,  A61B6/583 ,  G06T2211/424

    摘要： A system and method for tomographic image reconstruction using truncated projection data that allows exact interior reconstruction (interior tomography) of a region of interest (ROI) based on the known sparsity models of the ROI, thereby improving image quality while reducing radiation dosage. In addition, the method includes parallel interior tomography using multiple sources beamed at multiple angles through an ROI and that enables higher temporal resolution.

    摘要翻译： 基于ROI的已知稀疏模型，使用截断的投影数据进行断层图像重建的系统和方法，其允许感兴趣区域（ROI）的精确内部重建（内部层析成像），从而在降低辐射剂量的同时提高图像质量。 另外，该方法包括使用通过ROI以多个角度射束的多个源的并行内部层析成像，并且能够实现更高的时间分辨率。

    EXACT LOCAL COMPUTED TOMOGRAPHY BASED ON COMPRESSIVE SAMPLING
    8.
    发明申请
    EXACT LOCAL COMPUTED TOMOGRAPHY BASED ON COMPRESSIVE SAMPLING 有权
    基于压缩采样的局部计算机图像

    公开(公告)号：US20120063659A1

    公开(公告)日：2012-03-15

    申请号：US13264834

    申请日：2010-04-15

    申请人： Ge Wang ,  Hengyong Yu

    发明人： Ge Wang ,  Hengyong Yu

    IPC分类号： G06K9/00

    CPC分类号： G06T11/006 ,  A61B6/583 ,  G06T2211/424

    摘要： A system and method for tomographic image reconstruction using truncated projection data that allows exact interior reconstruction (interior tomography) of a region of interest (ROI) based on the known sparsity models of the ROI, thereby improving image quality while reducing radiation dosage. In addition, the method includes parallel interior tomography using multiple sources beamed at multiple angles through an ROI and that enables higher temporal resolution.

    摘要翻译： 基于ROI的已知稀疏模型，使用截断的投影数据进行断层图像重建的系统和方法，其允许感兴趣区域（ROI）的精确内部重建（内部层析成像），从而在降低辐射剂量的同时提高图像质量。 另外，该方法包括使用通过ROI以多个角度射束的多个源的并行内部层析成像，并且能够实现更高的时间分辨率。

    Interior Tomography and Instant Tomography by Reconstruction from Truncated Limited-Angle Projection Data
    10.
    发明申请
    Interior Tomography and Instant Tomography by Reconstruction from Truncated Limited-Angle Projection Data 失效
    通过截断的有限角度投影数据重建的内部层析成像和即时层析成像

    公开(公告)号：US20090196393A1

    公开(公告)日：2009-08-06

    申请号：US12362979

    申请日：2009-01-30

    申请人： Ge Wang ,  Yangbo Ye ,  Hengyong Yu

    发明人： Ge Wang ,  Yangbo Ye ,  Hengyong Yu

    IPC分类号： H05G1/60 ,  G06K9/00

    CPC分类号： G06T11/006 ,  A61B6/508 ,  G06T2211/416 ,  G06T2211/432 ,  G06T2211/436

    摘要： A system and method for tomographic image reconstruction using truncated limited-angle projection data that allows exact interior reconstruction (interior tomography) of a region of interest (ROI) based on the linear attenuation coefficient distribution of a subregion within the ROI, thereby improving image quality while reducing radiation dosage. In addition, the method includes parallel interior tomography using multiple sources beamed at multiple angles through an ROI and that enables higher temporal resolution.

    摘要翻译： 一种使用截断的有限角度投影数据进行断层图像重建的系统和方法，其基于ROI内的子区域的线性衰减系数分布，允许感兴趣区域（ROI）的精确内部重建（内部层析成像），从而提高图像质量 同时减少辐射剂量。 另外，该方法包括使用通过ROI以多个角度射束的多个源的并行内部层析成像，并且能够实现更高的时间分辨率。