公开(公告)号：US12016871B2

公开(公告)日：2024-06-25

申请号：US17249976

申请日：2021-03-19

Applicant: GR BIOSYSTEMS, INC.

Inventor： Andrew J. Gross ,  Shane Ririe

IPC: A61K31/7034 ,  A61K9/00 ,  A61K31/12 ,  A61K31/121 ,  A61K31/16 ,  A61K31/4164 ,  A61K31/43 ,  A61K31/65 ,  A61K31/7048 ,  A61K31/7052 ,  A61K31/7056 ,  A61K47/34 ,  A61P35/00

CPC classification number: A61K31/7034 ,  A61K9/0014 ,  A61K9/0053 ,  A61K9/0063 ,  A61K31/12 ,  A61K31/121 ,  A61K31/16 ,  A61K31/4164 ,  A61K31/43 ,  A61K31/65 ,  A61K31/7048 ,  A61K31/7052 ,  A61K31/7056 ,  A61K47/34 ,  A61P35/00

Abstract: The present disclosure generally relates to compositions that inhibit matrix metalloproteinases (MMPs). These compositions may be particularly useful in treating oral cancer or an oropharyngeal cancer. The compositions can be prepared as a topical formulation, ointment, mouthwash, or packaged in a syringe.