公开(公告)号：US20190388364A1

公开(公告)日：2019-12-26

申请号：US16545567

申请日：2019-08-20

Applicant: GRÜNENTHAL GMBH

Inventor： Johannes SCHNEIDER ,  Thomas CHRISTOPH

IPC: A61K31/137 ,  A61K9/00 ,  A61K47/12

Abstract: The invention relates to a pharmaceutical composition comprising Tapentadol or a physiologically acceptable salt thereof for use in local anesthesia.

公开(公告)号：US20200009083A1

公开(公告)日：2020-01-09

申请号：US16516856

申请日：2019-07-19

Applicant: Grünenthal GmbH

Inventor： Klaus SCHIENE ,  Ilona STEIGERWALD ,  Michel HAMON ,  Johannes SCHNEIDER ,  Silvia REINARTZ ,  Ulrich JAHNEL ,  Thomas TZSCHENTKE

IPC: A61K31/137 ,  A61K9/00

Abstract: The use of tapentadol in the treatment of pain and/or pain chronification in a subject suffering from pain chronification and/or in the treatment of pain and inhibition of pain chronification in a subject suffering from pain and at risk of pain chronification, as well as the use of tapentadol for the treatment or inhibition of migraine.