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公开(公告)号：US20220273735A1
公开(公告)日：2022-09-01
申请号：US17511689
申请日：2021-10-27
发明人： Hsieh-Hsun Ho , Wen-Yang Lin , Yi-Wei Kuo , Yen-Yu Huang , Jia-Hung Lin , Chi-Huei Lin , Cheng-Ruei Liu , Shu-Hui Chen
IPC分类号： A61K35/747 , A61P31/04 , C12N1/20
摘要： The invention provides a method of increasing an amount of oral immunoglobulin A (IgA) and/or inhibiting oral pathogens in a subject in need thereof, which utilizes a composition including a therapeutically effective amount of probiotics as an effective ingredient. The probiotics include Lactobacillus plantarum LPL28, which can efficiently increase the amount of oral IgA and/or inhibit the oral pathogens, and thus have a potential to prevent teeth cavities and/or periodontal diseases.
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公开(公告)号：US11969450B2
公开(公告)日：2024-04-30
申请号：US17730665
申请日：2022-04-27
发明人： Hsieh-Hsun Ho , Jui-Fen Chen , Yi-Wei Kuo , Chi-Huei Lin
IPC分类号： A61K35/747 , A23L33/135 , A61K35/745
CPC分类号： A61K35/747 , A23L33/135 , A61K35/745 , A23V2002/00 , A23V2400/175 , A23V2400/515 , A23V2400/529 , A23V2400/531 , A23V2400/533
摘要： Disclosed herein are methods for improving gastrointestinal barrier function, alleviating a gastrointestinal barrier dysfunction-associated disorder, and inhibiting growth of enteric pathogenic bacteria using a composition containing Lactobacillus rhamnosus MP108, Bifidobacterium longum subsp. infantis BLI-02, and Bifidobacterium animalis subsp. lactis BB-115, which are deposited at the China General Microbiological Culture Collection Center (CGMCC) respectively under accession numbers CGMCC 21225, CGMCC 15212, and CGMCC 21840. A number ratio of Lactobacillus rhamnosus MP108, Bifidobacterium longum subsp. infantis BLI-02, and Bifidobacterium animalis subsp. lactis BB-115 ranges from 1:0.2:0.67 to 1:9:9.
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公开(公告)号：US11759487B2
公开(公告)日：2023-09-19
申请号：US17511689
申请日：2021-10-27
发明人： Hsieh-Hsun Ho , Wen-Yang Lin , Yi-Wei Kuo , Yen-Yu Huang , Jia-Hung Lin , Chi-Huei Lin , Cheng-Ruei Liu , Shu-Hui Chen
IPC分类号： A01N63/00 , A61K35/747 , C12N1/20 , A61P31/04 , C12R1/25
CPC分类号： A61K35/747 , A61P31/04 , C12N1/20 , C12R2001/25
摘要： The invention provides a method of increasing an amount of oral immunoglobulin A (IgA) and/or inhibiting oral pathogens in a subject in need thereof, which utilizes a composition including a therapeutically effective amount of probiotics as an effective ingredient. The probiotics include Lactobacillus plantarum LPL28, which can efficiently increase the amount of oral IgA and/or inhibit the oral pathogens, and thus have a potential to prevent teeth cavities and/or periodontal diseases.
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公开(公告)号：US12005091B2
公开(公告)日：2024-06-11
申请号：US17726843
申请日：2022-04-22
发明人： Hsieh-Hsun Ho , Wen-Yang Lin , Jui-Fen Chen , Yi-Wei Kuo , Jia-Hung Lin , Chi-Huei Lin , Ching-Wei Chen , Yu-Fen Huang
IPC分类号： A61K35/747 , A61P31/04
CPC分类号： A61K35/747 , A61P31/04
摘要： The present invention discloses a method for maintaining or improving gastrointestinal condition, which includes: administering a lactic acid bacterial composition to a subject in need thereof, wherein the lactic acid bacterial composition comprises: a Lactobacillus paracasei ET-66 strain with a deposition number CGMCC 13514. The present invention also discloses a method for maintaining or improving gastrointestinal condition, which includes: administering a lactic acid bacterial fermentation composition to a subject in need thereof, wherein the lactic acid bacterial fermentation composition comprises: a fermentation product of a Lactobacillus paracasei ET-66 strain.
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公开(公告)号：US11957722B2
公开(公告)日：2024-04-16
申请号：US17688024
申请日：2022-03-07
发明人： Hsieh-Hsun Ho , Yi-Wei Kuo , Wen-Yang Lin , Jia-Hung Lin , Yen-Yu Huang , Chi-Huei Lin , Shin-Yu Tsai
IPC分类号： A61K35/747 , A23L33/135 , A61K8/99 , A61Q19/08 , C12N1/20 , C12R1/225
CPC分类号： A61K35/747 , A23L33/135 , A61K8/99 , A61Q19/08 , C12N1/205 , C12R2001/225
摘要： The present invention discloses an anti-aging composition, which includes: (a) isolated lactic acid bacterial strains or a fermented product thereof; and (b) an excipient, a diluent, or a carrier; wherein the isolated lactic acid bacterial strains include: Bifidobacterium bifidum VDD088 strains, Bifidobacterium breve Bv-889 strains, and Bifidobacterium longum BLI-02 strains. The present invention further provides a method for preventing aging by administering the foregoing anti-aging composition to a subject in need thereof.
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6.发明授权公开(公告)号：US11779615B2
公开(公告)日：2023-10-10
申请号：US17378955
申请日：2021-07-19
发明人： Chi-Chang Huang , Mon-Chien Lee , Yi-Ju Hsu , Hsieh-Hsun Ho , Yi-Wei Kuo , Wen-Yang Lin , Jia-Hung Lin , Chi-Huei Lin
IPC分类号： A61K35/747 , A61P3/04 , C12N1/20 , A23L33/135 , A61K35/745
CPC分类号： A61K35/747 , A23L33/135 , A61K35/745 , A61P3/04 , C12N1/205
摘要： The present invention provides a lactic acid bacteria composition, which comprises: a Lactobacillus plantarum PL-02 strain, a Lactobacillus acidophilusTYCA06 strain, a Lactobacillus casei CS-773 strain, and a physiologically acceptable excipient, diluent, or carrier. All of the strains are deposited at the China General Microbiological Culture Collection Center.
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公开(公告)号：US20230173000A1
公开(公告)日：2023-06-08
申请号：US17688024
申请日：2022-03-07
发明人： Hsieh-Hsun Ho , Yi-Wei Kuo , Wen-Yang Lin , Jia-Hung Lin , Yen-Yu Huang , Chi-Huei Lin , Shin-Yu Tsai
IPC分类号： A61K35/747 , A61K8/99 , A23L33/135 , C12N1/20 , A61Q19/08
CPC分类号： A61K35/747 , A61K8/99 , A23L33/135 , C12N1/205 , A61Q19/08 , C12R2001/225
摘要： The present invention discloses an anti-aging composition, which includes: (a) isolated lactic acid bacterial strains or a fermented product thereof; and (b) an excipient, a diluent, or a carrier; wherein the isolated lactic acid bacterial strains include: Bifidobacterium bifidum VDD088 strains, Bifidobacterium breve Bv-889 strains, and Bifidobacterium longum BLI-02 strains. The present invention further provides a method for preventing aging by administering the foregoing anti-aging composition to a subject in need thereof.
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