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公开(公告)号：US20220273735A1
公开(公告)日：2022-09-01
申请号：US17511689
申请日：2021-10-27
发明人： Hsieh-Hsun Ho , Wen-Yang Lin , Yi-Wei Kuo , Yen-Yu Huang , Jia-Hung Lin , Chi-Huei Lin , Cheng-Ruei Liu , Shu-Hui Chen
IPC分类号： A61K35/747 , A61P31/04 , C12N1/20
摘要： The invention provides a method of increasing an amount of oral immunoglobulin A (IgA) and/or inhibiting oral pathogens in a subject in need thereof, which utilizes a composition including a therapeutically effective amount of probiotics as an effective ingredient. The probiotics include Lactobacillus plantarum LPL28, which can efficiently increase the amount of oral IgA and/or inhibit the oral pathogens, and thus have a potential to prevent teeth cavities and/or periodontal diseases.
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公开(公告)号：US11957722B2
公开(公告)日：2024-04-16
申请号：US17688024
申请日：2022-03-07
发明人： Hsieh-Hsun Ho , Yi-Wei Kuo , Wen-Yang Lin , Jia-Hung Lin , Yen-Yu Huang , Chi-Huei Lin , Shin-Yu Tsai
IPC分类号： A61K35/747 , A23L33/135 , A61K8/99 , A61Q19/08 , C12N1/20 , C12R1/225
CPC分类号： A61K35/747 , A23L33/135 , A61K8/99 , A61Q19/08 , C12N1/205 , C12R2001/225
摘要： The present invention discloses an anti-aging composition, which includes: (a) isolated lactic acid bacterial strains or a fermented product thereof; and (b) an excipient, a diluent, or a carrier; wherein the isolated lactic acid bacterial strains include: Bifidobacterium bifidum VDD088 strains, Bifidobacterium breve Bv-889 strains, and Bifidobacterium longum BLI-02 strains. The present invention further provides a method for preventing aging by administering the foregoing anti-aging composition to a subject in need thereof.
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公开(公告)号：US11911421B2
公开(公告)日：2024-02-27
申请号：US17455466
申请日：2021-11-18
发明人： Hsieh-Hsun Ho , Wen-Yang Lin , Yi-Wei Kuo , Yen-Yu Huang , Jia-Hung Lin
IPC分类号： A61K35/745 , A61K35/747 , A61P3/10 , C12N1/20 , C12R1/225
CPC分类号： A61K35/745 , A61K35/747 , A61P3/10 , C12N1/205 , C12R2001/225
摘要： Disclosed herein is a probiotic composition that includes Lactobacillus salivarius subsp. salicinius AP-32, Lactobacillus johnsonii MH-68, and Bifidobacterium animalis subsp. lactis CP-9, which are deposited at the China Center for Type Culture Collection (CCTCC) respectively under accession numbers CCTCC M 2011127, CCTCC M 2011128, and CCTCC M 2014588. A number ratio of Lactobacillus salivarius subsp. salicinius AP-32, Lactobacillus johnsonii MH-68, and Bifidobacterium animalis subsp. lactis CP-9 ranges from 1:0.1:0.1 to 1:1:8. Also disclosed herein is use of the probiotic composition for alleviating type 1 diabetes mellitus (T1DM).
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公开(公告)号：US11801274B2
公开(公告)日：2023-10-31
申请号：US17885189
申请日：2022-08-10
发明人： Hsieh-Hsun Ho , Yi-Wei Kuo , Yen-Yu Huang , Jia-Hung Lin , Ko-Chiang Hsia , Ching-Wei Chen , Shin-Yu Tsai
IPC分类号： A61K35/745 , A61P29/00 , A23L33/135
CPC分类号： A61K35/745 , A23L33/135 , A61P29/00
摘要： Disclosed herein is a method for alleviating atopic dermatitis using a composition containing at least one lactic acid bacterial strain. The at least one lactic acid bacterial strain is selected from the group consisting of Lactobacillus salivarius subsp. salicinius AP-32 which is deposited at the China Center for Type Culture Collection (CCTCC) under an accession number CCTCC M 2011127, and Bifidobacterium animalis subsp. lactis CP-9 which is deposited at the CCTCC under an accession number CCTCC M 2014588.
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公开(公告)号：US20230173000A1
公开(公告)日：2023-06-08
申请号：US17688024
申请日：2022-03-07
发明人： Hsieh-Hsun Ho , Yi-Wei Kuo , Wen-Yang Lin , Jia-Hung Lin , Yen-Yu Huang , Chi-Huei Lin , Shin-Yu Tsai
IPC分类号： A61K35/747 , A61K8/99 , A23L33/135 , C12N1/20 , A61Q19/08
CPC分类号： A61K35/747 , A61K8/99 , A23L33/135 , C12N1/205 , A61Q19/08 , C12R2001/225
摘要： The present invention discloses an anti-aging composition, which includes: (a) isolated lactic acid bacterial strains or a fermented product thereof; and (b) an excipient, a diluent, or a carrier; wherein the isolated lactic acid bacterial strains include: Bifidobacterium bifidum VDD088 strains, Bifidobacterium breve Bv-889 strains, and Bifidobacterium longum BLI-02 strains. The present invention further provides a method for preventing aging by administering the foregoing anti-aging composition to a subject in need thereof.
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公开(公告)号：US12005090B2
公开(公告)日：2024-06-11
申请号：US17449699
申请日：2021-10-01
发明人： Hsieh-Hsun Ho , Ching-Wei Chen , Yu-Fen Huang , Yi-Wei Kuo , Wen-Yang Lin , Yen-Yu Huang
IPC分类号： A61K35/747 , A23L33/135 , A61K35/745 , A61P3/04
CPC分类号： A61K35/747 , A23L33/135 , A61K35/745 , A61P3/04
摘要： Disclosed herein is a probiotic composition including Lactobacillus salivarius subsp. salicinius AP-32 that is deposited at the China Center for Type Culture Collection (CCTCC) under an accession number CCTCC M 2011127, and Bifidobacterium longum subsp. longum OLP-01 that is deposited at the China General Microbiological Culture Collection Center (CGMCC) under an accession number CGMCC 17345. Also disclosed herein are use of at least one of the abovementioned lactic acid bacterial strains for treating obesity and/or an obesity-related disorder, and for inhibiting fat absorption.
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公开(公告)号：US11759487B2
公开(公告)日：2023-09-19
申请号：US17511689
申请日：2021-10-27
发明人： Hsieh-Hsun Ho , Wen-Yang Lin , Yi-Wei Kuo , Yen-Yu Huang , Jia-Hung Lin , Chi-Huei Lin , Cheng-Ruei Liu , Shu-Hui Chen
IPC分类号： A01N63/00 , A61K35/747 , C12N1/20 , A61P31/04 , C12R1/25
CPC分类号： A61K35/747 , A61P31/04 , C12N1/20 , C12R2001/25
摘要： The invention provides a method of increasing an amount of oral immunoglobulin A (IgA) and/or inhibiting oral pathogens in a subject in need thereof, which utilizes a composition including a therapeutically effective amount of probiotics as an effective ingredient. The probiotics include Lactobacillus plantarum LPL28, which can efficiently increase the amount of oral IgA and/or inhibit the oral pathogens, and thus have a potential to prevent teeth cavities and/or periodontal diseases.
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公开(公告)号：US11730779B2
公开(公告)日：2023-08-22
申请号：US17669752
申请日：2022-02-11
发明人： Hsieh-Hsun Ho , Yi-Wei Kuo , Jia-Hung Lin , Hui-Shan Wang , Yen-Yu Huang , Wen-Yang Lin , Ko-Chiang Hsia
IPC分类号： A61K35/747 , A61P3/00 , A61K35/745 , A61N5/06 , A61K35/00 , A61P31/04
CPC分类号： A61K35/747 , A61K35/745 , A61N5/0621 , A61P3/00 , A61P31/04 , A61K2035/115
摘要： The present invention provides a lactic acid bacterial composition for inhibiting the activity of Escherichia coli and/or treating or preventing jaundice, the composition including: a Bifidobacterium animalis subsp. lactis CP-9 strain and a Lactobacillus salivarius subsp. salicinius AP-32 strain. The present invention further provides a method for inhibiting growth of Escherichia coli, the method including the step(s) of: administering the foregoing lactic acid bacterial composition to a subject in need thereof. The present invention additionally provides a method for treating or preventing jaundice, the method including the step(s) of: administering the foregoing lactic acid bacterial composition to a subject in need thereof.
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