公开(公告)号：US20210332137A1

公开(公告)日：2021-10-28

申请号：US17224865

申请日：2021-04-07

Applicant: Five Prime Therapeutics, Inc.

Inventor： Sandeep P. INAMDAR ,  Helen L. COLLINS ,  Hong XIANG ,  Xiang ZHANG ,  Neyssa MARINA

IPC: C07K16/28 ,  A61P35/00

Abstract: The present disclosure provides methods of administering antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4 to a subject in need thereof, for example, a cancer patient, in combination with a PD-1/PD-L1 antagonist, such as an anti-PD-1 antibody.

公开(公告)号：US20210070862A1

公开(公告)日：2021-03-11

申请号：US16997581

申请日：2020-08-19

Applicant: Five Prime Therapeutics, Inc.

Inventor： Sandeep P. INAMDAR ,  Helen L. COLLINS ,  Xiang ZHANG ,  Hong XIANG

IPC: C07K16/28 ,  A61P35/00

Abstract: The present disclosure provides methods of administering antibodies and antigen-binding fragments thereof that specifically bid to human B7-H4 to a subject in need thereof, for example, a cancer patient.

公开(公告)号：US20210340214A1

公开(公告)日：2021-11-04

申请号：US17271792

申请日：2019-08-28

Applicant: FIVE PRIME THERAPEUTICS, INC.

Inventor： Sandeep P. INAMDAR ,  Kristen PIERCE ,  Hong XIANG ,  Susannah D. BARBEE

IPC: C07K14/705 ,  A61P35/00 ,  A61K9/00 ,  A61K31/7012 ,  C07K16/18

Abstract: The present disclosure provides methods of administering fusion proteins comprising the extracellular domain of human cluster of differentiation 80 (CD80) and the fragment crystallizable (Fc) domain of human immunoglobulin G 1 (IgG1) to a subject in need thereof, for example, a cancer patient.