公开(公告)号：US20210323904A1

公开(公告)日：2021-10-21

申请号：US17273357

申请日：2019-12-16

申请人： FIRMENICH SA

发明人： Denis Jacoby ,  Lucia Bonomo

IPC分类号： C07C67/327 ,  C07C69/716

摘要： Described herein is a process for the preparation of a mixture of compounds of formula having a weight ratio of the cis-diastereomers to trans-diastereoisomers higher than 1:1, where R1 represents a C1-8 alkyl group, a C2-8 alkenyl group or a C2-8 alkynyl group, each optionally substituted with one or two of a C1-4 alkyl alkoxy ether group and/or a C1-4 alkyl carboxylester group and R2 represents a C1-6 alkyl, a C2-6 alkenyl or a C2-6 alkynyl group, each optionally substituted with a C1-4 alkyl alkoxy ether group, a carboxylic acid group or a C1-4 alkyl carboxylester group and compounds suitable in the process.

公开(公告)号：US11339113B2

公开(公告)日：2022-05-24

申请号：US17273357

申请日：2019-12-16

申请人： FIRMENICH SA

发明人： Denis Jacoby ,  Lucia Bonomo

IPC分类号： C07C67/327 ,  C07C69/716

摘要： Described herein is a process for the preparation of a mixture of compounds of formula having a weight ratio of the cis-diastereomers to trans-diastereoisomers higher than 1:1, where R1 represents a C1-8 alkyl group, a C2-8 alkenyl group or a C2-8 alkynyl group, each optionally substituted with one or two of a C1-4 alkyl alkoxy ether group and/or a C1-4 alkyl carboxylester group and R2 represents a C1-6 alkyl, a C2-6 alkenyl or a C2-6 alkynyl group, each optionally substituted with a C1-4 alkyl alkoxy ether group, a carboxylic acid group or a C1-4 alkyl carboxylester group and compounds suitable in the process.

公开(公告)号：US10899694B2

公开(公告)日：2021-01-26

申请号：US16307665

申请日：2017-06-26

申请人： Firmenich SA

发明人： Denis Jacoby ,  Jean-Jacques Riedhauser ,  Philippe Miranda ,  Harvey Randall ,  Fabrice Keller

IPC分类号： C07C45/65 ,  B01J23/00 ,  B01J23/44 ,  C07C67/317 ,  C07C49/597 ,  C07C49/603 ,  C07C49/637 ,  C07C69/738

摘要： The present invention relates to the field of organic synthesis and more specifically it concerns a process for the dehydrogenation of compound of formula (I) catalyzed by palladium (Pd0) in elemental metallic form.

公开(公告)号：US10858370B2

公开(公告)日：2020-12-08

申请号：US16637484

申请日：2018-10-08

申请人： FIRMENICH SA

发明人： Denis Jacoby ,  Peter Fankhauser

IPC分类号： C07D493/08

摘要： Described herein is a process for preparing a compound of formula (I) starting from a compound of formula (II), where the process is catalyzed by a Ruthenium complex.

公开(公告)号：US12103898B2

公开(公告)日：2024-10-01

申请号：US18007339

申请日：2021-07-26

申请人： Firmenich SA

发明人： Denis Jacoby ,  Philippe Dupau ,  Lucia Bonomo ,  Simone Chappuis ,  Virginie Blanchard

IPC分类号： C07C1/20 ,  C07C1/213

CPC分类号： C07C1/213 ,  C07C2523/44

摘要： The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) catalyzed by a nickel complex. The compound of formula (II) is also part of the invention.

公开(公告)号：US12037341B2

公开(公告)日：2024-07-16

申请号：US17299405

申请日：2020-04-09

申请人： FIRMENICH SA

发明人： Denis Jacoby ,  Catherine Gandara

IPC分类号： C07D493/08

CPC分类号： C07D493/08

摘要： Described herein is a process for preparing a compound of formula (I)




starting from a compound of formula (II)





where the process is catalyzed by a metal complex.

公开(公告)号：US20200255443A1

公开(公告)日：2020-08-13

申请号：US16637484

申请日：2018-10-08

申请人： FIRMENICH SA

发明人： Denis Jacoby ,  Peter Fankhauser

IPC分类号： C07D493/08

摘要： Described herein is a process for preparing a compound of formula (I) starting from a compound of formula (II), where the process is catalyzed by a Ruthenium complex.