公开(公告)号：US20190070116A1

公开(公告)日：2019-03-07

申请号：US16174311

申请日：2018-10-30

申请人： Fresenius Medical Care Deutschland GmbH

发明人： Thierry EYRARD ,  Philippe LAFFAY ,  Benoit LUAIRE

IPC分类号： A61K9/16 ,  A61M1/16 ,  A61K33/14 ,  A61K31/7004 ,  A61K31/194

摘要： The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container (10) comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit.

公开(公告)号：US20240269360A1

公开(公告)日：2024-08-15

申请号：US18645730

申请日：2024-04-25

申请人： FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

发明人： Thierry EYRARD ,  Philippe LAFFAY ,  Benoit LUAIRE

IPC分类号： A61M1/16 ,  A61K9/00 ,  A61K9/08 ,  A61K33/14 ,  B01F21/00 ,  B01F21/10 ,  B01F23/50 ,  B01F23/53 ,  B01F25/50 ,  B01F25/52 ,  B01F35/21

CPC分类号： A61M1/1656 ,  A61K9/08 ,  A61K33/14 ,  B01F21/02 ,  B01F21/10 ,  B01F23/53 ,  B01F25/50 ,  B01F25/52 ,  B01F35/2117 ,  B01F35/2133 ,  B01F35/2134 ,  A61K9/0019 ,  A61M2205/3393 ,  B01F21/30 ,  B01F23/511 ,  B01F23/56

摘要： The invention relates to a method for manufacturing a liquid acid concentrate for hemodialysis machines, with the following steps. In a preliminary step a water source (120), an acid source (130), an electrolyte tank (140) containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source (150) are connected to a mixing tank (110). During Step a), the quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank (110). At Step b), the quantity of acid needed for manufacture the liquid acid concentrate is introduced into the mixing tank (110), the solution is stirred until a homogeneous solution is obtained. Step c) is to repeat Sub-steps c1) and c2) until the electrolyte mixture contained in the electrolyte tank is completely dissolved. At Sub-step c1) part of the solution contained in the mixing tank (110) is transferred into the electrolyte tank (140) containing the electrolyte mixture, then at Sub-step c2) the solution contained in the electrolyte tank (140) is transferred into the mixing tank, leaving the still solid constituents in the electrolyte tank. At Step d) the quantity of sodium chloride needed to manufacture the liquid acid concentrate is introduced into the mixing tank (110). Finally, at Step e), the solution is stirred and recirculated by taking it from the bottom the mixing tank (110) and reintroducing it at the top of the mixing tank until a homogeneous liquid acid concentrate is obtained. Steps a) to d) can be performed in any order, Step a) preceding always Step c).

公开(公告)号：US20170007541A1

公开(公告)日：2017-01-12

申请号：US15116947

申请日：2015-02-05

申请人： FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

发明人： Thierry EYRARD ,  Philippe LAFFAY ,  Benoit LUAIRE

IPC分类号： A61K9/16 ,  A61M1/16 ,  A61K31/194 ,  A61K33/14 ,  A61K31/7004

CPC分类号： A61K9/16 ,  A61K9/1682 ,  A61K31/194 ,  A61K31/7004 ,  A61K33/14 ,  A61M1/1656 ,  A61M1/1666 ,  A61M1/1668 ,  A61K2300/00

摘要： The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container (10) comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit.

摘要翻译： 本发明涉及一种用于透析液的新型干酸浓缩物（DAC）和由所述浓缩物制成的可用于纯化血液的透析液。 本发明还涉及制备干酸浓缩物以及透析液的方法。 它还涉及包含所述酸浓缩物的容器（10），并且在某些实施方案中 - 特别适用于透析单元。