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公开(公告)号：US20170007541A1
公开(公告)日：2017-01-12
申请号：US15116947
申请日：2015-02-05
发明人： Thierry EYRARD , Philippe LAFFAY , Benoit LUAIRE
IPC分类号： A61K9/16 , A61M1/16 , A61K31/194 , A61K33/14 , A61K31/7004
CPC分类号： A61K9/16 , A61K9/1682 , A61K31/194 , A61K31/7004 , A61K33/14 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61K2300/00
摘要： The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container (10) comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit.
摘要翻译： 本发明涉及一种用于透析液的新型干酸浓缩物（DAC）和由所述浓缩物制成的可用于纯化血液的透析液。 本发明还涉及制备干酸浓缩物以及透析液的方法。 它还涉及包含所述酸浓缩物的容器（10），并且在某些实施方案中 - 特别适用于透析单元。
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公开(公告)号：US20220023146A1
公开(公告)日：2022-01-27
申请号：US17296992
申请日：2019-11-26
摘要： The invention relates to a bag (1) made of a flexible wall, which bag is fitted with an inlet fluid line for introducing dissolution water, and with an outlet fluid line (121, 122) for extracting a solution obtained. According to the invention, the inside of the bag has a lower edge (13) in the overall shape of a V, the point of the V being further away from the centre of the bag than the arms of the V, the outlet fluid line opening into the bag as close as possible to the point of the V.
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公开(公告)号：US20220001162A1
公开(公告)日：2022-01-06
申请号：US17291286
申请日：2019-11-04
摘要： The invention relates to a connector (1) constituted by: base provided with a tubular wall (13) closed by a bottom wall (11) provided with at least one through-opening (111); a membrane provided with a flexible wall (23) having a central opening, a tubing (22) placed in the opening of the flexible wall; sealing means for preventing a liquid from leaving the connector through the tubing. The base and the membrane are fixed to each other in a liquid-tight manner. The flexible wall allows axial displacement of the tubing so that it can be moved between a closed position, in which a liquid cannot leave the connector through the conduit of the tubing, and an open position, in which a liquid from can leave the connector through the tubing. Retaining means (121, 222a) maintain the tubing (22) closed with a force that can be overcome manually to open it.
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公开(公告)号：US20220339334A1
公开(公告)日：2022-10-27
申请号：US17642290
申请日：2020-09-10
发明人： Winfried BREHM , Philippe LAFFAY , Gerhard WIESEN
IPC分类号： A61M1/16
摘要： The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.
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公开(公告)号：US20220313881A1
公开(公告)日：2022-10-06
申请号：US17642268
申请日：2020-09-10
发明人： Winfried BREHM , Philippe LAFFAY , Gerhard WIESEN
摘要： The present invention refers to a container comprising a connection portion allowing for an easy, efficient and more hygienic connection of the container to a fluid dosing unit of a blood treatment device. According to the present invention the fluid dosing unit comprises a valve that fluidically closes the fluid dosing unit if no container is connected to the fluid dosing unit and that opens the fluid dosing unit upon connection of a container to the fluid dosing unit. Thus, undesired spillages potentially arising upon disconnection of the container from the fluid dosing unit can be avoided.
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公开(公告)号：US20190070116A1
公开(公告)日：2019-03-07
申请号：US16174311
申请日：2018-10-30
发明人： Thierry EYRARD , Philippe LAFFAY , Benoit LUAIRE
IPC分类号： A61K9/16 , A61M1/16 , A61K33/14 , A61K31/7004 , A61K31/194
摘要： The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container (10) comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit.
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7.发明公开公开(公告)号：US20240269360A1
公开(公告)日：2024-08-15
申请号：US18645730
申请日：2024-04-25
发明人： Thierry EYRARD , Philippe LAFFAY , Benoit LUAIRE
IPC分类号： A61M1/16 , A61K9/00 , A61K9/08 , A61K33/14 , B01F21/00 , B01F21/10 , B01F23/50 , B01F23/53 , B01F25/50 , B01F25/52 , B01F35/21
CPC分类号： A61M1/1656 , A61K9/08 , A61K33/14 , B01F21/02 , B01F21/10 , B01F23/53 , B01F25/50 , B01F25/52 , B01F35/2117 , B01F35/2133 , B01F35/2134 , A61K9/0019 , A61M2205/3393 , B01F21/30 , B01F23/511 , B01F23/56
摘要： The invention relates to a method for manufacturing a liquid acid concentrate for hemodialysis machines, with the following steps. In a preliminary step a water source (120), an acid source (130), an electrolyte tank (140) containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source (150) are connected to a mixing tank (110). During Step a), the quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank (110). At Step b), the quantity of acid needed for manufacture the liquid acid concentrate is introduced into the mixing tank (110), the solution is stirred until a homogeneous solution is obtained. Step c) is to repeat Sub-steps c1) and c2) until the electrolyte mixture contained in the electrolyte tank is completely dissolved. At Sub-step c1) part of the solution contained in the mixing tank (110) is transferred into the electrolyte tank (140) containing the electrolyte mixture, then at Sub-step c2) the solution contained in the electrolyte tank (140) is transferred into the mixing tank, leaving the still solid constituents in the electrolyte tank. At Step d) the quantity of sodium chloride needed to manufacture the liquid acid concentrate is introduced into the mixing tank (110). Finally, at Step e), the solution is stirred and recirculated by taking it from the bottom the mixing tank (110) and reintroducing it at the top of the mixing tank until a homogeneous liquid acid concentrate is obtained. Steps a) to d) can be performed in any order, Step a) preceding always Step c).
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公开(公告)号：US20240261560A1
公开(公告)日：2024-08-08
申请号：US18024781
申请日：2021-09-10
发明人： Philippe LAFFAY , Francois DUMONT-D'AYOT , Benoit LUAIRE , Winfried BREHM , Martin KAISER , Paul SEIT , Rafael STERZER
CPC分类号： A61M39/26 , A61M1/1666 , A61M39/10
摘要： The present invention relates to a closing element for a fluid line, preferably a fluid line of a concentrate container, comprising a closing portion configured to be arranged on an end portion of the fluid line to fluidically close the fluid line, wherein the closing portion comprises an intended breaking point, and a pressure receiving portion configured to receive pressure applied by a connector element to be fluidically connected to the fluid line by breaking the intended breaking point, wherein the pressure receiving portion comprises at least one protrusion projecting outwards from at least a part of the closing element that is configured to come into contact with the connector element.
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9.发明公开公开(公告)号：US20230320932A1
公开(公告)日：2023-10-12
申请号：US17909776
申请日：2021-03-10
发明人： Winfried BREHM , Philippe LAFFAY , Gerhard WIESEN , Paul SEIT , Rafael STERZER
CPC分类号： A61J1/1487 , A61M1/1666 , A61M1/1668 , A61M1/0218
摘要： The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.
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公开(公告)号：US20220355007A1
公开(公告)日：2022-11-10
申请号：US17642260
申请日：2020-09-10
发明人： Winfried BREHM , Philippe LAFFAY , Gerhard WIESEN
摘要： The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.
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