公开(公告)号：US11672431B2

公开(公告)日：2023-06-13

申请号：US16706688

申请日：2019-12-07

Applicant: Flint Hills Scientific, L.L.C.

Inventor： Ivan Osorio ,  Alexey Lyubushin ,  Didier Sornette

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/16 ,  A61B5/374 ,  A61B5/024 ,  A61B5/08 ,  A61B5/11 ,  A61B5/24 ,  A61B5/369 ,  A61B5/083 ,  A61B5/145

CPC classification number: A61B5/02055 ,  A61B5/0205 ,  A61B5/165 ,  A61B5/374 ,  A61B5/4094 ,  A61B5/4836 ,  A61B5/726 ,  A61B5/746 ,  A61B5/024 ,  A61B5/0816 ,  A61B5/0833 ,  A61B5/1118 ,  A61B5/14542 ,  A61B5/16 ,  A61B5/24 ,  A61B5/369

Abstract: A method, comprising receiving a time series of patient body signal, determining first and second sliding time windows for the time series; applying an autoregression algorithm, comprising: applying an autoregression analysis to each of the first and second windows, yielding autoregression coefficients and a residual variance for each window; estimating a parameter vector for each window based on the autoregression coefficients and residual variances; and determining a difference between the parameter vectors; and determining seizure onset and seizure termination based on the difference between the parameter vectors. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

公开(公告)号：US11219374B2

公开(公告)日：2022-01-11

申请号：US15729168

申请日：2017-10-10

Applicant: Flint Hills Scientific, L.L.C.

Inventor： Ivan Osorio ,  Alexey Lyubushin ,  Didier Sornette

IPC: G01N33/48 ,  G01N33/50 ,  A61B5/0205 ,  A61B5/16 ,  A61B5/00 ,  A61B5/374 ,  A61B5/024 ,  A61B5/08 ,  A61B5/11 ,  A61B5/24 ,  A61B5/369 ,  A61B5/083 ,  A61B5/145

Abstract: A method, comprising receiving a time series of patient body signal, determining first and second sliding time windows for the time series; applying an autoregression algorithm, comprising: applying an autoregression analysis to each of the first and second windows, yielding autoregression coefficients and a residual variance for each window; estimating a parameter vector for each window based on the autoregression coefficients and residual variances; and determining a difference between the parameter vectors; and determining seizure onset and seizure termination based on the difference between the parameter vectors. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

公开(公告)号：US20170143273A1

公开(公告)日：2017-05-25

申请号：US15377922

申请日：2016-12-13

Applicant: FLINT HILLS SCIENTIFIC, L.L.C.

Inventor： Ivan Osorio ,  Alexey Lyubushin ,  Didier Sornette

IPC: A61B5/00 ,  A61B5/0205

CPC classification number: A61B5/02055 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/04001 ,  A61B5/0476 ,  A61B5/048 ,  A61B5/0816 ,  A61B5/0833 ,  A61B5/1118 ,  A61B5/14542 ,  A61B5/16 ,  A61B5/165 ,  A61B5/4094 ,  A61B5/4836 ,  A61B5/726 ,  A61B5/746

Abstract: Methods for detecting a seizure, by use of a wavelet transform maximum modulus (WTMM) algorithm applied to body data. A non-transitive, computer-readable storage device for storing data that when executed by a processor, perform such a method.

公开(公告)号：US12226193B2

公开(公告)日：2025-02-18

申请号：US18202414

申请日：2023-05-26

Applicant: Flint Hills Scientific, L.L.C.

Inventor： Ivan Osorio ,  Alexey Lyubushin ,  Didier Sornette

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/16 ,  A61B5/374 ,  G06F17/10 ,  A61B5/024 ,  A61B5/08 ,  A61B5/083 ,  A61B5/11 ,  A61B5/145 ,  A61B5/24 ,  A61B5/369

Abstract: A method, comprising receiving a time series of patient body signal, determining first and second sliding time windows for the time series; applying an autoregression algorithm, comprising: applying an autoregression analysis to each of the first and second windows, yielding autoregression coefficients and a residual variance for each window; estimating a parameter vector for each window based on the autoregression coefficients and residual variances; and determining a difference between the parameter vectors; and determining seizure onset and seizure termination based on the difference between the parameter vectors. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

公开(公告)号：US11638528B2

公开(公告)日：2023-05-02

申请号：US16278064

申请日：2019-02-16

Applicant: Flint Hills Scientific, L.L.C.

Inventor： Ivan Osorio ,  Alexey Lyubushin ,  Didier Sornette

IPC: A61B5/0205 ,  A61B5/16 ,  A61B5/00 ,  A61B5/374 ,  A61B5/024 ,  A61B5/08 ,  A61B5/11 ,  A61B5/24 ,  A61B5/369 ,  A61B5/083 ,  A61B5/145

Abstract: A method, comprising receiving a time series of patient body signal, determining first and second sliding time windows for the time series; applying an autoregression algorithm, comprising: applying an autoregression analysis to each of the first and second windows, yielding autoregression coefficients and a residual variance for each window; estimating a parameter vector for each window based on the autoregression coefficients and residual variances; and determining a difference between the parameter vectors; and determining seizure onset and seizure termination based on the difference between the parameter vectors. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.