知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

6 条记录 (耗时 0.01 秒)

    Pharmaceutically active compounds
    1.
    发明授权
    Pharmaceutically active compounds 失效
    药物活性化合物

    公开(公告)号：US3705945A

    公开(公告)日：1972-12-12

    申请号：US3705945D

    申请日：1970-05-07

    申请人： FISONS PHARMACEUTICALS LTD

    发明人： FITZMAURICE COLIN ,  LEE THOMAS BRIAN

    IPC分类号： C07D311/24 ,  A61K27/00

    CPC分类号： C07C45/673 ,  C07C45/64 ,  C07C45/67 ,  C07C45/71 ,  C07D311/24 ,  C07C49/82 ,  C07C49/835 ,  C07C49/84

    摘要： COMPOSITIONS CONTAINING NEW COMPOUNDS OF THE FORMULA

    ((2-(HO2C-),4-(O=),R1,R2,R3-4H-CHROMENYL)-O-X-O-),R4,R5,

    R5 ,2-(HO2C-),4-(O=)-4H-CHROMENE

    AND FUNCTIONAL DERIVATIVES THEREOF, IN WHICH AT LEAST ONE OF R1, R2, R3, R4,R5 AND R6 IS A SUBSTITUENT OTHER THAN A HYDROGEN ATOM, HALOGEN ATOM OR ALKYL OR SUBSTITUTED ALKYL GROUP, AND THE REMAINDERS OF R1, R2, R3, R4, R5 AND R6 ARE AND R6 ARE THE SAME OR ARE DIFFERENT AND EACH IS HYDROGEN OR A SBUSTITUENT OTHER THAN HYDROGEN, AND X IS A STRAIGHT OR BRANCHED POLYMETHYLENE CHAIN WHICH MAY BE INTERRUPTED BY ONE OR MORE CARBOCYCLIC OR HETEROCYCLIC RINGS, OXYGEN ATOMS OR CARBONYL GROUPS, POSSESS SPECIAL ACTIVITIES AS INHIBITORS OF THE EFFECTS OF CERTAIN TYPES OF ANTIGEN-ANTIBODY REACTION.

    Bis-phenoxy compounds
    2.
    发明授权
    Bis-phenoxy compounds 失效
    双酚氧化合物

    公开(公告)号：US3686320A

    公开(公告)日：1972-08-22

    申请号：US3686320D

    申请日：1968-09-25

    申请人： FISONS PHARMACEUTICALS LTD

    发明人： FITZMAURICE COLIN ,  LEE THOMAS BRIAN

    IPC分类号： C07C45/67 ,  C07C45/71 ,  C07C49/84 ,  C07D311/16 ,  C07D311/22 ,  C07D311/24 ,  C07C49/78

    CPC分类号： C07D311/24 ,  C07C45/63 ,  C07C45/673 ,  C07C45/71 ,  C07C49/84 ,  C07D311/16 ,  C07D311/22 ,  Y10S514/826

    摘要： Compounds of the formula h WHEREIN Z and Z'' are hydroxy and Y and Y'' are H, -COCH3, or COOR'' (R'' being an alkyl group) are used to prepare compounds of the formula AND THERAPEUTICALLY ACCEPTABLE SALTS, ESTERS AND AMIDES THEREOF, WHEREIN R1, R2, R3, R4, R5 and R6 are the same or different and each is H or halogen, lower alkyl, hydroxy, lower alkoxy, substituted lower alkyl or substituted lower alkoxy, and X is a saturated or unsaturated, substituted or unsubstituted, straight or branched polymethylene chain which may be interrupted by one or more carbocyclic rings or oxygen-containing heterocyclic rings, oxygen atoms or carbonyl groups. The latter compounds are useful as inhibitors of certain antigen-antibody reactions, being particularly useful for the relief and prophylaxis of asthma.

    摘要翻译： 式WHEREIN Z和Z'的化合物是羟基，Y和Y'是H，-COCH 3或-COOR'（R'是烷基）用于制备下式的化合物和可治疗的盐，酯和氨基酸 其中R 1，R 2，R 3，R 4，R 5和R 6相同或不同，各自为H或卤素，低级烷基，羟基，低级烷氧基，取代的低级烷基或取代的低级烷氧基，X为饱和或不饱和的， 可被一个或多个碳环或含氧杂环，氧原子或羰基中断的取代或未取代的直链或支链多亚甲基链。 后一种化合物可用作某些抗原 - 抗体反应的抑制剂，特别适用于缓解和预防哮喘。

    Bis-coumarinyl compounds
    5.
    发明授权
    Bis-coumarinyl compounds 失效
    二氧化锰化合物

    公开(公告)号：US3567741A

    公开(公告)日：1971-03-02

    申请号：US3567741D

    申请日：1968-11-21

    申请人： FISONS PHARMACEUTICALS LTD

    发明人： FITZMAURICE COLIN ,  LEE THOMAS BRIAN

    IPC分类号： C07D311/16 ,  C07D7/20

    CPC分类号： C07D311/16

    摘要： THE INVENTION PROVIDES THE BIS-COUMARINYL COMPOUNDS OF THE FORMULA:

    4-T,5-R,6-Q,7-((2-(O=),4-T1,5-R1,6-Q1,8-P1-

    2H-CHROMEN-7-YL)-O-X-O-),8-P-2H-CHROMEN-2-ONE

    WHEREIN Q, R, Q1 AND R1 MAY BE SAME OR DIFFERENT AND EACH IS SELECTED FROM HYDROGEN; ALKYL, ALKOXY, SUBSTITUTED ALKYL AND ALKOXY; HYDROXY AND HALOGEN; P AND P1 ARE SELECTED FROM HYDROGEN AND ACYL; T AND T1 MAY BE THE SAME OR DIFFERENT AND EACH IS SELECTED FROM ALKYL AND ARYL; AND X IS A SATURATED OR UNSATURATED, SUBSTITUTED OR UNSUBSTITUTED, STRAIGHT OR BRANCHED HYDROCARBON CHAIN, ANY CARBON OF WHICH MAY BE REPLACED BY ONE OR MORE CARBOCYCLIC OR HETEROCYCLIC RINGS, CARBONYL GROUPS OR OXYGEN ATOMS.